Term
| Human genmoe project has helped.... |
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Definition
-us determine what protiens are encoded in our DNA
-humans share basic biological processed with other organisms
-us learn that human genmoes from different individuals contain virutally same set of genes (ignoring sex gene differences)
-us learn human genomes contain different alleles |
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Term
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Definition
-all of the protiens in a particular cell at a time
-proteome from each cell in your body contains different protiens
-genome same but proteome different |
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Term
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Definition
| complete set of genetic material--some exceptions, all genome in body are same |
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Term
| single nucleotide polymorphism |
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Definition
| sites in human genome where individuals differ by a single base |
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Term
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Definition
-sequence obtained is expanding the type and power of medical diagnositc tests
-small percentage of 3 billion bases in hgp encode protiens
-involed many countries |
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Term
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Definition
-particular side by side arrangement of bases along the DNA strand
-order spells out exact instructions required to create a particular organism with its own unique traits |
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Definition
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Term
| results of DNA sequencing |
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Definition
results are a list of the order of the building blcoks
-ACCTGCCATC
-we have 3 billion of these
-all on different chromosomes |
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Term
| what is DNA sequencing used for? |
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Definition
-can tell us genetic similarities and differences
-can tell us how we compare to different organisms
-used to predict protein coding genes
-does not tell us when or where genes are expressed
-tells us what protiens do |
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Term
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Definition
-enzymes encoded by these genes are responsible for metabolizing most drugs used today
-affects patient responses to both drug and dose |
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Term
| cytochrome p450's importance in medicine |
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Definition
-everyone has these
-there are many differnt genes
-many differnt alleles for each gene
-knowing patiens CP450 will allow for better drug dose |
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Term
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Definition
-based on sequences from human genome project
-allow for rapid identification of specific sequence |
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Term
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Definition
-can determine which genes are expressed during disease
-can identify SNPs or alleles you carry
-which CP450 alleles a patient has
-allows to see if you have alleles for specific disorder |
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