Term
|
Definition
| -the scientific evalutaion of new drugs, therapies, or treatments |
|
|
Term
| which type of therapy involves decreasing the amount of specific mRNA inside specific cells in the patients body? |
|
Definition
|
|
Term
| before clinical trials are started |
|
Definition
-scienfitic evidence must support safety
-typically requires previose tests in animal models
-require approval and monitoring by panels |
|
|
Term
|
Definition
-test an experimental drug or treatment
-small group of people (20-80)
-evaluate its safety
-determine a safe dosage range
-identify side affects |
|
|
Term
|
Definition
-a larger group of people (100-300)
-test if is effective
-further evaluate its safety |
|
|
Term
|
Definition
-large groups of people (1000-3000)
-confirm effectivness
-monitor side effects
-compare it to commonly used treatments
-collect info that will allow experimental drug or treatment to be used safely |
|
|
Term
|
Definition
-post marketing studies
-drugs risks, benefits, and optimal use |
|
|
Term
| informed consent clinical trials |
|
Definition
-participants freely agree to participate
-they understand risk, benefits, duration, rights, responsibilites, ect. |
|
|
Term
|
Definition
| -error in genetic code which means they cannot produce a protien--patient injected with protein |
|
|
Term
|
Definition
| -injecting genes that will make protein do its job--produces protein |
|
|
Term
vector
transciption
promoter |
|
Definition
-delivers to cells
-transcribes promoter to make protein
-has to be expressed in cell |
|
|
Term
| cystic fibrosis review: zygote has two alleles of gene which causes CF. zygote is ff. what is true about zygote? |
|
Definition
-prior to mitosis, two new copies of disease alles will be made my DNA replication
-expression of the CF gene using transcription will produce mRNA containging the errors that cause CF
-translation of this mRNA will produce protiens that don't function properly causeing CF |
|
|
