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Introduction
Sources for drug information
63
Pharmacology
Graduate
09/20/2012

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Term
primary literature definition
Definition
original publication and consists of research studies, case reports, editorial sna letters to the editor; detiled description of the study design, methodology and scientific results
Term
advantages of primary literature
Definition
curretn, original and "cutting-edge; pertains to patient-oritnetd, evidence-based medicine; unbiased views and suggestions to improve the quality of the report
Term
examples of primary literature
Definition
articles presented in new england journal of medicine, journal of the american medical association, archives of internal medicine, annals of internal medicine, lancet, british medical journal and more.
Term
disadvantages of primary literature
Definition
flaws in study methodology may lead to inaccurate conclusions; inappropriate statistical analysis; kowledge of scientific methods and stats is necessary and may take time before wide acceptance
Term
utilizing primary literature
Definition
cautious, careful and conservative, is it peer-reviewed? be sure all aspect are understood, patient population mentioned corresponds to your practice population, case reports only relate to one patient, not a whole pt pop
Term
define secondary literature
Definition
compile by indexing and abstracting services; bibliographic info by topic; databases each with own scope, look, fee, and features to make it easy for he user to search the database
Term
utilizing secondary literature
Definition
each has its own focus, and collects a certain field about a disease, drug info or literature; sometimes you need a subscription to get access, provides author, title of the work, location and date of the publication, can use clinical medical librarians if not well acquainted with the medical subject headings; "find it at UMKC" button
Term
advantages of secondary literature
Definition
quick access, large scope and/or concise info; peer reviewed; updated info can be sent periodically
Term
disadvantages of secondary literature
Definition
publication adn inclusion from days to weeks; number of journals indexed depends on scope; must be proficient at sifting through search techniques; utilize specific search terms and be proficient with a particular database's search techniques
Term
examples of secondary literature
Definition
OVID, Medline, The Medical letter, Iowa Drug information Service, International pharmaceutical abstracts, The Chochrane Library (collaboration)
Term
OVID
Definition
collection of scientific, medical and technical databases
Term
The Medical letter
Definition
abstracting and evaluatin service that reviews recently approved medications, drug classes and lists current treatment options
Term
MEDLINE
Definition
over 4000 journals of iternational biomedical literature; abstracitng service
Term
Iowa Drug Information Service
Definition
articles relevant to drugs and treatment of disease from approximately 200 journals
Term
international pharmaceutical abstracts
Definition
extensive list of indexed info pertaining to international pharmacy and pharmaceutical sciences
Term
The Cochrane Library
Definition
assessment of the literature on particular health care topics; complete and thorough literature review
Term
define tertiary literature
Definition
genearlly well-established info that is approved and accepted by the FDA, or well founded in the primary care literature; textbooks on various drugs or disease topics or review articles that thoroughly summarize a particular topic
Term
advantages of tertiary literature
Definition
convenient and accessible, drug info on specific subjects, well accepted in medical practice
Term
disadvantages of tertiary literature
Definition
time passes before the info is available; space limitations; emphasize limited info about a topic/drug; may present info that is based on less than thorough review; may not be referenced appropriately; may not be the most accurate and reliable; any updated info may need to be inserted into the printed copy
Term
evaluation of tertiary literature
Definition
assess the text for timeliness; assess consistency by comparing info to aother text; evaluate credentials of author; check the resource's references
Term
pharmacology and drug info resources
Definition
goodman and gillman's pharmacological basis of therapeutics; basic and clinical pharmacology; american hospital formulary service; drug facts and comparisons; handbook on injectable drugs; drug info handbook; handook of clinical drug data; martindale: the complete drug reference; micromedex; clinical pharmacology; physician's desk reference; USPDI volume I: drug info for the health care provider; drug topics red book
Term
drug interaction resources
Definition
drug interaction facts; hansten and horn's drug interaction analysis and management
Term
medical and pharmacy therapeutics resources
Definition
the washington manual of medical therapeutics; applied therapeutics: the clinical use of drugs; pharmacotherapy: a phathophysiologic approach; textbook of therapeutics: drug and disease management
Term
information on drug side effects
Definition
meyler's side effects on drugs
Term
drug information resources for special patient populations
Definition
harriet lane handbook: a manual for pediatrics house officers; handbook of comonly prescribed pediatric drugs; handbook of geriatric drug therapy; drug prescribing in renal failure; drugs in pregnancy and lacttion; cancer chemotherapy handbook; the review of natural products; natural standard database
Term
other information resources
Definition
remington: the science and practice of pharmacy; USPDI volume II: advice for the patient; USPDI volume III; approved drug products and legal requirements
Term
drug information and poison control centers
Definition
UMKC drug information center; poison control centers: kansas-mid-america poison control center; cardinal glennon children's hospital poison center
Term
goodman and gillman's pharmacological basis of therapeutics
Definition
action, absorption distribution and metabolism
Term
basic and clinical pharmacology
Definition
complete and comprehensive general pharmacology text
Term
american hospital formulary service
Definition
FDA approved and non-labeled uses; dosage and usage sections
Term
drug facts and comparisons
Definition
FDA approved drugs and investigational and orphan agents; legend and OTC listings
Term
handbook on injectable drugs
Definition
drug stability and compatibility
Term
drug information handbook
Definition
drugs by generic name; algorithms and tables of vrious information
Term
handbook of clinical drug data
Definition
drug info; listings of drugs by class; tables and disease state sections
Term
martindale: the complete drug reference
Definition
foreign drug information; obscure information and for names of drugs in other countries
Term
micromedex
Definition
pharmacology, therapeutics, poison info, etc.
Term
clinical pharmacology
Definition
extensive, peer-reviewed, urrent, accurate drug info; full-text info on generic, brand, herbal or investigational drugs
Term
physician's desk reference
Definition
usage and dosage info only as approved by the FDA; pictures and tablet and capsule marking for some drugs
Term
USPDI volume I: drug info for the health care provider
Definition
FDA approved and som non-label uses; auxiliary labeling
Term
drug topics red book
Definition
wholesale prices or legend and OTC; manufacturer's phone numbers; "do not crush or chew" list
Term
drug interaction facts
Definition
drug/drug and dru/food interaction as well as clinical significance
Term
hansten and horn's drug interaction analysis nd management
Definition
introductory chapter provides discussion on mechanisms for drug interactions
Term
the washington manual of medical therapeutics
Definition
treatment of disease states and medical emergencies; charts and tables
Term
applied therapeutics: the clinical use of drugs
Definition
pathophysiology and pharmacotherapeutics in a case presentation format; drug therapy
Term
pharmacotherapy: a pathophysiologic approach
Definition
pathophys and treatment of disease; drug therapy
Term
textbook of therapeutics: drug and disease management
Definition
drug and disease management; disease gropus
Term
meyler's side effects of drugs
Definition
lists and discusses side effect with drug therapy; index by drug and adverse drug reaction
Term
harriet lane handbook: a manual for pediatrics house officers
Definition
pocket guide to pediatrics, including drug dosing
Term
handbook of commonly prescribed pediatric drugs
Definition
pediatric drug therapy
Term
handbook of geriatric drug therapy
Definition
alphabetically by drug name
Term
drugs prescribing in renal failure
Definition
all aspects of drug dosing in renal failure including recommended dosages of individual drugs
Term
drugs in pregnancy and lactation
Definition
all aspects of drug dosing in pregnancy and lactation
Term
cancer chemotherapy handbook
Definition
pharmacology and use of chemotherapeutic agents
Term
the review of natural products
Definition
referenced, evaluated, factual info about natural products
Term
natural standard database
Definition
online in full text; alternative, complementary and integrative medicine
Term
remington: the science andpractice of pharmacy
Definition
the practice of pharmacy and pharmaceutical sciences
Term
USPDI volume II
Definition
patient education
Term
USPDI volume III
Definition
acts and regulations; A and B ratings; older drugs and discontinued drugs
Term
information from experts
Definition
great wisdom and clinical "pearls"; out of date, biased; make sure it makes good medical sense and best evidence, and experience parallels patient population
Term
review articles
Definition
needs to be reviewed very carefully for author or organization bias
Term
hospital based treatment plans
Definition
ensure that patients with certain problems are treated correctly ad uniformly; conform to what is currently recommended
Term
pharmacists
Definition
excellent drug info source; only a licenses pharmacise not a technician or student; ask which resources they utilized
Term
pharmaceutical companies
Definition
may be very biased; always ask that it be backed up by sound scientific evidence
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