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Introduction
Pharmaceutical Calculations
52
Pharmacology
Undergraduate 1
09/16/2012

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Term
Prescriptions should include
Definition
Date hen it was written, Name, address and age of the patient, superscription (Rx), inscription (drug, strength and any inert additives), subscription (directions for pharmacist), signature (directions for patient), refill information and signature of the prescriber
Term
what information about the prescriber should be included on a prescription?
Definition
name, telephone number, address and DEA number on the prescription
Term
prescriptions should be writtin with a _____ in the ____ system
Definition
pen/ink, metric system
Term
1 mL= how many drops?
Definition
15
Term
1 tsp= ? mL
Definition
5 mL
Term
1 Tbsp= ? mL
Definition
15 mL
Term
2 Tbsp= ?mL
Definition
30 mL
Term
1 teacup full = ? mL
Definition
180 mL
Term
1 glassful = ? mL
Definition
240 mL
Term
1 fluid oz = ? mL
Definition
29.57 mL
Term
1 pint = ? mL
Definition
473 mL
Term
1 gallon = ? mL
Definition
3785 mL
Term
1 pound= ? g
Definition
454 g
Term
1 oz= ? g
Definition
28.35 g
Term
1 kg = ? lbs
Definition
2.2 lbs
Term
1 grain= ? mg
Definition
64 mg
Term
1 gram = ? grains
Definition
15.432
Term
1 inch = ? cm
Definition
2.54 cm
Term
1 mile = ? km
Definition
1.6
Term
1 meter = ? inches
Definition
39.37 in
Term
1 cm = ? inch
Definition
0.4 inch
Term
1 mm = ? inch
Definition
0.04 inch
Term
what is a ratio?
Definition
relative magnitude of two similar quantities and if frequently defined as the quotient of two similar numbers
Term
what is a proportion?
Definition
equality of two ratios; ex: a:b = c:d and a/b = c/d
Term
percent weight- in-volume
Definition
number of grams of a medicaiton per 100 mL of liquide
Term
percent volume-in-volume
Definition
number of mL of medication per 100 mL of liquid
Term
percent weight-in-weight
Definition
number of grams per 100 g of solution or misxure
Term
how to solve percentage strength problems?
Definition
using a proportion
Term
what is a ratio strength?
Definition
expresses the amount of drug in solution as grams of drug perv olume espressed in mL; ex: 1:500 soln implies there is a 1 g present per 500 mL of solution
Term
how do you solve ratio strength problems?
Definition
using a proportion
Term
describe the method of dimensional analysis
Definition
quantity given x conversion factor for given quantity x conversion factor for desired quantity x conversion computation x quantity desired
Term
macrodrip amounts
Definition
10 drops/mL, 15 drops/mL or 20 drops/mL
Term
microdrip amounts
Definition
60 drops/mL
Term
equation for determining flow rates
Definition
gtt/min = [drop factor (gtt/mL0 x total volume (mL/hr)] / time in min per hr
Term
formula for microdrip infusion rate
Definition
[60 x weight adjusted dose x weight] / drug concentration
Term
formula for body surface area
Definition
[(BW in kG x Ht in cM0/3600] ^1/2
Term
why are body surface estimates employed?
Definition
with antineoplastics and for standardization (metabolic rate and renal function)
Term
why are body surface estimates employed?
Definition
with antineoplastics and for standardization (metabolic rate and renal function)
Term
how do you adjust a pt specific measurement to its value per 1.73 m^2
Definition
multiply the patint specific value by the ration [1.73/pts BSA]
Term
BMI is reported as
Definition
kg/m^2 = weight in kg/ height in m^2
Term
describe a quick conversion for pounds to kg
Definition
1) divide weight in lbs by 2;
2) take 10% of the number in step 1;
3) subtract the number in step 2 from the number in step 1
Term
how to convert F to C
Definition
C = 5/9 (F-32)
C= 5/9(F + 40) - 40
Term
convert C to F
Definition
F = 32 + 9/5 C
F = 9/5 (C + 40) - 40
Term
what is an equivalent?
Definition
weight of a substnace that combines with or replaces one gram atomic weight of hydrogen
Term
What is an equivalent weight?
Definition
determined by diving the formula weight by its valence
Term
what is a miliequivalent
Definition
multiplying the equivalent weight by 1/1000; used to express the concentration of eletrolytes in solution, specifically refers to the number of ionic charges in solution
Term
formula for calculating mEq
Definition
#mEg = (#mg x valence) / formula weight
Term
formula for amount of salt in an IV solution
Definition
g = (mEx/L x formula weight of salt (in g)) / (valence x 100)
Term
mOsmol for non-electolytes
Definition
equal to the formula weight; mOsm/L = g/L / formula weight x 1000
Term
mOsm/L for strong electrolytes
Definition
total particle number is influenced by the degree of dissociation; mOsm/L = g/L/ formula weight x number of ions x 1000
Term
list order of decreasing osmotic effect per gram of nutritional components
Definition
electrolytes > small organic molecules > dextrose oligosaccharides > starches > proteins > fats
Term
how do you solve problems for different dosage forms? ex if in a salt, ester or hydrate?
Definition
use a proportion!
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