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study of biological functions of the body |
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cell --> tissue --> organ --> system |
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-1813-1878 -French man that discovered the milieu intérieur (inside wall of your body) |
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the inside wall of your body |
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discovered the milieu intérieur (inside wall of your body) |
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one of the core concepts of physiology |
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-1871-1945) -developed the term homeostasis and studied some mechanisms of it |
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developed the term homeostasis and studied some mechanisms of it |
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Maintaining constancy of internal environment |
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set point within a certain normal range |
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some physiologic variables where there's a desired range |
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-blood pressure -blood glucose |
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what happens when the physiological parameters increase or decrease too much? |
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a loop is activated to reach homeostasis |
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how a loop to reach homeostasis is activated |
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-Sensor detects deviation from set point -Integrating center, often CNS, determines the response -Effector, often muscles or glands, produces the response; this is the target tissue |
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detects physiological deviation from set point |
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often the CNS, this determines the response to the physiological deviation from set point |
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often muscles or glands, this is the target tissue that produces the response to the physiological deviation from set point |
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How does the integrating center communicate with the effector tissues? |
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it usually boils down to signaling patways, which can be through the nervous system or through hormones, sometimes with crossover between the two types of pathways |
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Produces change in opposite direction to reverse the deviation so that homeostasis can be reached |
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an example of a negative feedback pathway |
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Homeostasis is achieved by... |
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negative feedback inhibition |
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Examples of physiological parameters that are regulated by negative feedback |
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the cells that make insulin |
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the beta cells in the pancreas |
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what's more common? positive or negative feedback? |
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when positive feedback is necessary |
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when something needs to be done urgently |
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Examples of processes that use positive feedback |
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-cervical dilation and oxytocin -clotting cascade |
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example of a positive feedback pathway |
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the 4 main types of tissue in the body |
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-Muscle -Nervous -Epithelial -Connective |
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the 3 types of muscle tissue |
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the 2 types of nervous tissue |
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Neurons are composed of... |
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-dendrites -cell body -axons |
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cells that form membranes and glands |
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hollow portion of an organ |
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spme organs that have a lumen |
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-respiratory tract -digestive tract |
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provide barrier between external and internal environments |
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______ forms the functional parenchyma of organs |
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epithelial tissue forms the ______ of organs |
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the functional tissue of an organ as distinguished from the connective and supporting tissue
for example, in the liver, the functional parenchyma is what does the metabolizing |
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some types of connective tissue |
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-connective tissue proper -bone -cartilage -blood |
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this is present between connective tissue cells |
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Cells + Extracellular Matrix |
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Extracellular Matrix (EM) composed of... |
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-protein fibers
-ground substance |
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at least two primary tissues |
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organs located in different regions of the body and perform related functions |
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molecules that usually need help crossing cell membranes |
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molecules that contain both polar (hydrophilic) head group and non-polar (hydrophobic) tail group |
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-RCOO-Na+
-Detergent action |
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some important amphipathic molecules |
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-Phospholipids -Bile acids (salts) |
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some functions of phospholipids |
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-Cell membrane structure -Transport of lipids in the blood -Functions and mechanisms of the pulmonary surfactants -Absorption of lipids into cells -Entry of steroids into cells |
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function of bile acids (salts) |
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some components of the cell membrane other than phospholipids |
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-lipids -proteins -carbohydrates |
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Membrane proteins serve as... |
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-pumps -enzymes -receptors -energy transducers |
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