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The study of the manner in which the function of living systems is affected by chemical substances. |
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Any chemical substance other than those required for normal sustenance which can exert a biological effect. |
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Drugs used to diagnose, treat or prevent disease or pregnancy in humans or to relieve signs and symptoms of disease without curing the underlying disease. |
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Those drugs which have been deemed appropriate for human use but require the care of a specially trained or licensed physician. |
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Those drugs that have been found safe for use without medical supervise. |
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Non prescription medicine (OTC) |
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A drug that is in the process of being researched to determine its efficacy and safety for use in human disease. |
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The name that describes the chemical makeup if a particular drug. |
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Related to the chemical name but us less cumbersome, independent of the manufacturer and often identifies the drug classification with similar suffixes or prefixes. Lower case. |
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The name assigned to the generic drug by the manufacturer. Capitalized. |
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Determines that the medication is free of contaminating particles. |
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Refers to relative strength of the drug, |
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Refers to the capability of the drug to produce the desired therapeutic response. |
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Refers to the difference between the safe and toxic doses of the drug, |
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The amount of drug that is a sorted and transported throughout the body. |
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"What the body does to the drug." The process by which a drug is absorbed, transported, metabolized, and excreted by the body. |
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Process by which a drug passes from the site of administration into the bloodstream for distribution into the tissues. |
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The process by which a drug gets from the bloodstream to the site of action. |
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The ability of a drug to bind to body proteins, namely albumin for transport through the body, |
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The mechanism of tight capillary junctions designed to protect the brain from harmful chemicals. |
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A drug which is capable of producing adverse if physical defects on a developing fetus. |
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How the body inactivates the drug and prepares it for elimination from the body. |
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An inactive drug that is given and undergoes metabolism in the body to an active drug which is then able to exert its effects. |
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The process by which one drugs metabolism is enhanced by the administration of another drug, the result is more rapid metabolism of the drug. |
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The process by which one drugs metabolism is blocked by another. The result is decreased metabolism of the drug and potential toxicity. |
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Harmful or dangerous effects on a person. |
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The process of a drug being eliminated by the body. |
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The length of time it takes for one-half of a medication to leave the body. |
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The drug balance experienced when the amount of drug given at each dosing interval is equal to the amount of the drug being eliminated from the body. |
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Steady state concentration |
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A larger than maintenance dose that is given to allow the patient to reach steady state concentration faster. |
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"What the drug does to the body". The process by which cell physiology is altered by a drug. |
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The degree of attraction between the receptor and the drug. |
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Drug which has an affinity for a receptor and activates that receptor upon binding, |
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A drug which has affinity for a receptor and activate that receptor without producing a response. |
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The amount of drug that must be given to elicit a response. |
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The length of time required for a drug to elicit a therapeutic response after dosing. |
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The point at which a medicine has reached its maximal effectiveness. |
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How long a medication will stay active and exert an effect in the patients body. |
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Types of effects that are less serious than adverse effects, are predictable, and may occur even at therapeutic doses. |
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A reaction of the immune system in which the body produces untold effects on the patient after receiving a sensitizing dose. (Rash or hives) |
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A life threatening response to medication which produces airway edema and hypotension. |
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An unexpected or exaggerated effect to a typical dose of a drug. |
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A measure of a drugs strength. Refers to difference between therapeutic and toxic level. |
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The largest effect a drug can produce. |
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A change in the responsiveness of the patient to drugs that occur over time which require more and more medication to be given in order to produced the desired response, |
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The rapid development of tolerance to a medication. |
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Refers to when a patient experiences a compulsion to have a medication and experiences withdrawal symptoms when unable to get medication, |
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A drug that has been shown to be capable of initiating a cancerous growth. |
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