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Intro to Pharmacology
Common definitions
47
Nursing
Undergraduate 1
09/25/2013

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Term
The study of the manner in which the function of living systems is affected by chemical substances.
Definition
Pharmacology
Term
Any chemical substance other than those required for normal sustenance which can exert a biological effect.
Definition
Drug
Term
Drugs used to diagnose, treat or prevent disease or pregnancy in humans or to relieve signs and symptoms of disease without curing the underlying disease.
Definition
Medicine
Term
Those drugs which have been deemed appropriate for human use but require the care of a specially trained or licensed physician.
Definition
Prescription Medicines
Term
Those drugs that have been found safe for use without medical supervise.
Definition
Non prescription medicine (OTC)
Term
A drug that is in the process of being researched to determine its efficacy and safety for use in human disease.
Definition
Investigational Drug
Term
The name that describes the chemical makeup if a particular drug.
Definition
Chemical name
Term
Related to the chemical name but us less cumbersome, independent of the manufacturer and often identifies the drug classification with similar suffixes or prefixes. Lower case.
Definition
Generic name
Term
The name assigned to the generic drug by the manufacturer. Capitalized.
Definition
Brand or trade name
Term
Determines that the medication is free of contaminating particles.
Definition
Purity
Term
Refers to relative strength of the drug,
Definition
Potency
Term
Refers to the capability of the drug to produce the desired therapeutic response.
Definition
Efficacy
Term
Refers to the difference between the safe and toxic doses of the drug,
Definition
Safety
Term
The amount of drug that is a sorted and transported throughout the body.
Definition
Bioavailability
Term
"What the body does to the drug." The process by which a drug is absorbed, transported, metabolized, and excreted by the body.
Definition
Pharmacokinetics
Term
Process by which a drug passes from the site of administration into the bloodstream for distribution into the tissues.
Definition
Absorption
Term
The process by which a drug gets from the bloodstream to the site of action.
Definition
Distribution.
Term
The ability of a drug to bind to body proteins, namely albumin for transport through the body,
Definition
Protein binding
Term
The mechanism of tight capillary junctions designed to protect the brain from harmful chemicals.
Definition
Blood-Brain Barrier
Term
A drug which is capable of producing adverse if physical defects on a developing fetus.
Definition
Teratogen
Term
How the body inactivates the drug and prepares it for elimination from the body.
Definition
Metabolism
Term
An inactive drug that is given and undergoes metabolism in the body to an active drug which is then able to exert its effects.
Definition
Prodrug
Term
The process by which one drugs metabolism is enhanced by the administration of another drug, the result is more rapid metabolism of the drug.
Definition
Induction
Term
The process by which one drugs metabolism is blocked by another. The result is decreased metabolism of the drug and potential toxicity.
Definition
Inhibition
Term
Harmful or dangerous effects on a person.
Definition
Toxicity
Term
The process of a drug being eliminated by the body.
Definition
Excretion
Term
The length of time it takes for one-half of a medication to leave the body.
Definition
Half-life
Term
The drug balance experienced when the amount of drug given at each dosing interval is equal to the amount of the drug being eliminated from the body.
Definition
Steady state concentration
Term
A larger than maintenance dose that is given to allow the patient to reach steady state concentration faster.
Definition
Loading dose
Term
"What the drug does to the body". The process by which cell physiology is altered by a drug.
Definition
Pharmacodynamics
Term
The degree of attraction between the receptor and the drug.
Definition
Affinity
Term
Drug which has an affinity for a receptor and activates that receptor upon binding,
Definition
Agonist
Term
A drug which has affinity for a receptor and activate that receptor without producing a response.
Definition
Antagonist
Term
The amount of drug that must be given to elicit a response.
Definition
Relative potency
Term
The length of time required for a drug to elicit a therapeutic response after dosing.
Definition
Onset of action
Term
The point at which a medicine has reached its maximal effectiveness.
Definition
Peak
Term
How long a medication will stay active and exert an effect in the patients body.
Definition
Duration of action
Term
Types of effects that are less serious than adverse effects, are predictable, and may occur even at therapeutic doses.
Definition
Side effects
Term
A reaction of the immune system in which the body produces untold effects on the patient after receiving a sensitizing dose. (Rash or hives)
Definition
Allergic reactions
Term
A life threatening response to medication which produces airway edema and hypotension.
Definition
Anaphylactic response
Term
An unexpected or exaggerated effect to a typical dose of a drug.
Definition
Idiosyncratic
Term
A measure of a drugs strength. Refers to difference between therapeutic and toxic level.
Definition
Therapeutic index
Term
The largest effect a drug can produce.
Definition
Maximal efficacy
Term
A change in the responsiveness of the patient to drugs that occur over time which require more and more medication to be given in order to produced the desired response,
Definition
Tolerance
Term
The rapid development of tolerance to a medication.
Definition
Tachyphylaxis
Term
Refers to when a patient experiences a compulsion to have a medication and experiences withdrawal symptoms when unable to get medication,
Definition
Addiction
Term
A drug that has been shown to be capable of initiating a cancerous growth.
Definition
Carcinogen
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