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Definition
enclosing barrier environmental protection allows motion produces adnexal structures temperature regulation storage of water, electrolytes, vitamins, fats, carbs, protein pigmentation immunosurveillance antimicrobial sensory perception secretion/excretion vitamin D production |
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pH gradient exists upper stratum corneaum 7.0 upper granular layer 7.5 due to filaggrin breakdown products, amino acids, fatty acids, alpha hydroxy acids |
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alkalinization factors include CO2 and bicarbonate from sweat excitement can increase pH |
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relatively alkaline pH of dog skin thought to play a role in susceptibility of dogs to skin infections |
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Definition
(outside to inside) stratum corneum stratum lucidum (only on foot pads) stratum granulosum stratum spinosum stratum basale |
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Dermal Layers of the Skin |
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Definition
made of fibers, ground substance, fibroblasts, mast cells, histiocytes glands of the skin, claws, hair |
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Definition
forehead, dorsal neck, dorsal trunk, rump, tail base |
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pinnae, axillary region, inguinal region, perianal region |
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Definition
originate from neural crest located in stratum basale and spread tentacles into outer layers of the skin one for every 10-20 kertinocytes coloration, photoprotection, scavenging cytotoxical radicals, inflammation constituative pigmentation determined by genetics facultative pigmenttion determined by stimuli |
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white hairs at the tip, brown/black shaft, and yellow or red brown base |
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Definition
UV light activates tyrosinase Tyrosinase turns tyrosine into melanin |
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Definition
sebaceous and sweat glands arrector pili muscle |
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Definition
only have sebaceous gland emerge through same pore |
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Definition
anagen: growth phase catagen: transition phase telogen: resting phase |
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Definition
provide significant diagnostic information develop as a result of underlying disease |
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Definition
primary lesion small changes in coloration less than 1 cm in diameter hyperpigmentation or red or loss of pigmentation |
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Definition
primary lesion changes in coloration larger than 1 cm in diameter |
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primary lesion flat topped circular raise area of skin associated with allergic reactions |
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Definition
primary lesion larger areas of subcutaneous edema associated with allergic reactions |
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Definition
primary lesion small red raised lesion associated with early inflammatory stage or allergic reaction bites or developing pustule |
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Definition
primary lesion associated with bacterial infection or immune mediated diseases located within stratum corneum within epidermis accumulation of neutrophils or eosinophils |
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Definition
primary lesion located within epidermis arge fluid filled structure vesicle is small blister less than 1 cm bulla is larger than 1 cm associated with viral and immune mediated diseses |
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Definition
primary lesion localized circumscribed area associated with infiltration of cells in epidermis large and hard neoplastic or inflammatory cells |
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primary lesion neoplastic cells that obliterate normal structure of skin |
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Definition
may develop from primary lesion or result from self-trauma |
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secondary lesion loss of hair |
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Definition
secondary lesion dandruff accumulation of stratum corneum on skin surface dry skin, scratching, infection |
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Definition
secondary lesion circular scales footprint of ruptured vesicle or pustule |
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Definition
secondary lesion accumulation of exfoliated stratum corneum cells and inflammatory cells |
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Definition
secondary lesion draining tracts associated with deeper skin infections into the dermis associated with ruptured hair follicles |
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Definition
secondary lesion neutrophils and macrophages penetrating injury |
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Definition
secondary lesion post inflammatory associated with erythema |
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secondary lesion scratches caused by the animal usually jsut on epidermis |
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Definition
secondary lesion goes through epidermis and dermis |
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secondary lesion erosion are superficial ulcer is loss of epidermis and dermis |
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Definition
secondary lesion skin is healed with fibrous connective tisuse epidermis is not regenerated |
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secondary lesion whole epidermis is thicker than normal hyperplasia of those upper laters exaggerated skin markings stratum spinosum, basal, corneum are thick |
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Definition
secondary lesion thickening of just stratum corneum |
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Definition
secondary lesion sloughing of dead tissue |
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secondary lesion hair follicle that has lost hair shaft and is plugged with secretions and exfoliated skin |
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