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Intro to Behavioral Neuroscience Final
Intro to Behavioral Neuroscience Final (Ch. 5, 13, 14, 15)
108
Psychology
Undergraduate 3
05/09/2011

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Term

 

 

 

Cooperativity

Definition

 

 

Nearly simultaneous stimulation by two or more axons produces Long Term Potentiation much more strongly than does repeated stumulation by just one axon

 

(A property of Long Term Potentiation)

Term
Natural Killer Cells
Definition

A type of leukocyte

 

Attacks tumor cells and cells that are infected with viruses.

Term
Diachisis
Definition

Means "to shock throughout"

 

The decreased activity of surviving neurons after damage to other neurons. 

Term
If axons from the retina were prevented from showing spontaneous activity during early development, what would be the probable effect on development of the lateral geniculate?
Definition
Axons will attach, but will not be fine-tuned based on experience. Therefore, connections are less precise.
Term
Damage to insula/insular cortex
Definition
Not disgusted by gross food, doesnt recognize faces showing disgust, does not perceive retching sounds as unpleasant
Term
How do people with Pre Frontal Cortex and amygdala damage perform in the Iowa Gambling Task?
Definition
They show difficulties processing emotional information. No nervous tension from decks with high negative payout. They fail to anticipate unpleasantness of likely outcomes, which leads to bad decisions.
Term
How do people with Pre Frontal Cortex and amygdala damage perform in the Iowa Gambling Task?
Definition
They show difficulties processing emotional information. No nervous tension from decks with high negative payout. They fail to anticipate unpleasantness of likely outcomes, which leads to bad decisions.
Term
Rumbaugh
Definition
Tried to teach a bonobo named Matata to press lit symbols which represented words. Matata's children learned from observation and performed much better at the task than Matata herself.
Term
Stop signal task
Definition
People watch a screen or listen for a tune. When they see something or hear a tune, they are supposed to press a button as fast as possible. Sometimes another stimulus occurs a split second after the first stimulus which means they are not supposed to press the button. A test of inhibition. those with ADHD do poorly on this test.
Term
What happened to children who were exposed to a lot of low spatial input at a young age?
Definition
Their systems stabilized too soon and it changed the way and speed the eyeball grew. This led to vision problems. They pruned too early and less than they should have.
Term
Configural Learning
Definition
Hippocampus is neccesary for it. The meaning of a stimulus depends on what other stimuli are paired with it.
Term
Sperry
Definition
Monitored the newt's neurons in the eye. Specific retina spots mapped to specific tectum spots. He rotated the newt's eye 180 degrees, and saw that axons were still able to map to the correct tectum spots.
Term
Sperry
Definition
Monitored the newt's neurons in the eye. Specific retina spots mapped to specific tectum spots. He rotated the newt's eye 180 degrees, and saw that axons were still able to map to the correct tectum spots.
Term
How does the amygdala enhance the startle reflex?
Definition
Auditory information (such as a loud noise) goes to the cochlear nucleus in the medulla and goes to the pons which causes muscles to tense, especially the neck muscles.
Term
Neural Darwinism
Definition
We start with more neurons and synapses than we keep. Synapses form haphazardly and then a selection process keeps some and rejects others.
Term
Migration
Definition
The process of cells moving toward their eventual destinations in the brain.
Term
Amygdala damage in monkeys
Definition
Causes them to be tame and placid, less fearful of flame, and they pick up objects that they normally avoid
Term
How is alcohol an anxiety reducer?
Definition
Alcohol promotes the flow of Cl- ions through GABA receptor complex and facilitates GABA binding. Anti-anxiety, intoxicating effects.
Term
Deafferented
Definition
When a limb loses its afferent (sensory) input.
Term
Hebbian synapse
Definition
A synapse that increases in effectiveness because of simultaneous activity in the presynaptic cell and postsynaptic neurons
Term
cross tolerance
Definition
an individual who has used one of a drug long enough to develop a tolerance to it will show a partial tolerance to other depressant drugs as well
Term
Nerve Growth Factor
Definition
Promotes survival and growth of the axon. Without NGF, the cell body dies.
Term
visuospatial sketchpad
Definition
stores visual information
(Part of working memory)
Term
Levi Montalcini Quote
Definition
"Wayfinding works via chemical gradients"
Developing neurons are sensitive to chemical gradients
Term
Choice delay task
Definition
Given a choice between one reward now or a slightly better reward later.
Those with ADHD choose the more immediate reward
Term
Stress (2 definitions)
Definition
1) The nonspecific response of the body to any demand made upon it
2) Events that are interpreted as threatening to an individual and which elicit physiological and behavioral responses
Term
Stress (2 definitions)
Definition
1) The nonspecific response of the body to any demand made upon it
2) Events that are interpreted as threatening to an individual and which elicit physiological and behavioral responses
Term
How do epinephrine and cortisol enhance memory storage?
Definition
They enhance emotional memories by stimulating the amygdala
Term
Penumbra
Definition
Latin for "almost shadow."
The region that surrounds the immediate damage.
Term
Long Term Potentiation
Definition
One or more axons connected to a dendrite bombard it with a brief but rapid series of stimuli (100 per second for 1 to 4 seconds). The burst of intense stimulation leaves some of the synapses potentiated (more responsive to new input of the same type) for minutes, days, or weeks
Term
Lateral Interpositus nucleus
Definition
A nucleus of the cerebellum
Term
Mass action
Definition
The cortex works as a whole, and the more cortex the batter (one of Lashley's principles)
Term
Valzelli
Definition
Isolated male mice for 4 weeks. This increased their aggressive behavior and decreased their serotonin turnover. The lowest turnover was in strains that fought the most.
Term
Dyslexia
Definition
Specific impairment of reading in a person with adequate vision and adequate skill performance in other areas
Term
associativity
Definition
Pairing a weak input with a strong input enhances later response to the weak input
Term
Damage to the amygdala
Definition
"rabies" symptoms
Kluver-Bucy syndrome
"fearlessness"
Inability to learn/potentiate fear responses
fear conditioning doesnt work
Term
Kluver Bucy syndrome
Definition
in monkeys: placid, tame, less fear
in humans: react to emotional stimuli inappropriately
Term
limbic system
Definition
the forebrain areas surrounding the thalamus.
has been regarded as critical for emotion
Term
Brief Stress: ______::prolonged stress:_______
Definition
________: sympathetic nervous system::__________:HPA axis
Term
disuse supersensitivity
Definition
heightened sensitivity as a result of inactivity by an incoming axon
Term
Long-term depression (in synapses)
Definition
prolonged decrease in response at a synapse. Occurs when axons have been active at a low frequency.
Term
neurotrophin
Definition
a chemical that promotes the survival and activity of neurons
Term
neurotrophin
Definition
a chemical that promotes the survival and activity of neurons
Term
AMPA & NMDA receptors
Definition
responsive to glutamate
Term
Changes Calcium creates in dendrites of the hippocampus (4)
Definition
- More AMPA receptors are created or moved
- More dendritic branches are formed
- Maybe more NMDA receptors are created
- Maybe AMPA receptors become more responsive
Term
How can stress lead to damage in the hippocampus?
Definition
High cortisol levels can damage cells in the hippocampus and impair memory because cortisol enhances metabolic activity which makes the brain more vulnerable to damage by toxins or overstimulation
Term
Phantom limb
Definition
a continuing sensation of an amputated body part
Term
focal hand dystonia
Definition
Fingers become clumsy, fatigue easily, and make involuntary movements that interfere with the task. A career ender for some musicians.
Term
Wernicke's aphasia
Definition
Fluent Aphasia. Impaired ability to remember the names of objects. Impaired language comprehension. Nonsensical speech, omitting nouns and verbs.
Term
Equipotentiality
Definition
All parts of the cortex contribute equally to complex behaviors such as learning; any part of the cortex can substitute for any other.
Term
Chicks imprinting study
Definition
Some species of chicks imprint on auditory input. When birds are exposed to early visual input (hole in shell), it makes the imprint weaker. They payed less attention to auditory input.
Term
HM
Definition
HM had many epileptic seizures. His hippocampus was removed.

- Anterograde amnesia, some retrograde
- No episodic memories
- Impaired declarative memory
- Intact procedural memory
- Better implicit memory than explicit
Term
Central executive
Definition
Directs attention toward one stimulus over another and determines which items will be stored in working memory (part of working memory)
Term
intermittent explosive disorder
Definition
a condition marked by occasional outbursts of violent behavior with little or no provocation
Term
ontogeny recapitulates phylogeny
Definition
change across your life time is a summary of change across evolution
Term
denervation supersensitivity
Definition
heightened sensitivity to a neurotransmitter after the destruction of an incoming axon
Term
GABA
Definition
main inhibitory transmitter, inhibits anxiety
Term
How sensitization works
Definition
1) Strong stimulation excites a facilitating interneuron
2) which releases serotonin onto presynaptic terminals of sensory neurons
3)serotonin attaches to receptors and potassium channels close.
4) prolonged action potention leads to more neurotransmitter
Term
3 components of working memory
Definition
1) phonological loop
2)visuospatial sketchpad
3)central executive
Term
B cells
Definition
leukocytes. Found mostly in bone marrow. Creates antibodies that attach to antigens and fights unfamiliar antigens.
Term
T cells
Definition
A type of leukocyte. Mature in thymus gland. Attacks intruders directly and helps other T and B cells to multiply
Term
collateral sprouts
Definition
the new branches that attach to vacant synapses after a loss of a set of axons.
Term
enriched environment
Definition
more action and activity and stimulation than normal. Leads to thicker cortex and more dendritic branching and higher performance on learning tests.
Term
differentiate
Definition
form the axon and dendrites that provide the neuron its distinctive shape
Term
Process in the development of neurons
Definition
Proliferation
Migration
Differentiation
Myelination
Synaptogenesis
Term
Williams Syndrome
Definition
characterized by mental retardation in most regards, but in many cases, skillful use of language
Term
Phonological loop
Definition
stores auditory information, including words
(part of working memory)
Term
insular cortex/insula
Definition
strongly activated @ disgust or people that look disgusted. Also the primary taste cortex
Term
Habituation
Definition
a decrease in response to a stimulus that is presented repeatedly and accompanied by no chance in other stimule
Term
monoamine oxidase (MAO)
Definition
breaks down serotonin into inactive chemicals
Term
anomia
Definition
difficulty recalling names of objects
Term
engram
Definition
the physical representation of what has been learned
Term
language acquisition device
Definition
a built in mechanism for acquiring language (Chomsky & Pinker)
Term
Poverty of the stimulus argument
Definition
made by Chomsky. Children don't hear many examples of some of the grammatical structures they acquire and therefore they could not have learned them. Implies that we are born knowing grammar (but this isnt really possible because we couldnt know grammar for every language)
Term
attentional blink
Definition
the period of time after one stimulus has been presented when it is hard to process another stimulus. Those with ADHD have longer blinks.
Term
epigenesis
Definition
Psychology and Biology interacti
Term
spatial neglect
Definition
when people have damage on the right side of their brain, they have a tendency to ignore the left side of the body and its surroundings or the left side of objects
Term
Morris water maze task
Definition
a rat must swim through murky water to find a rest platform that is just under the surface.
Term
Proliferation
Definition
the forming of brain cells, neurons, and glia
Term
How could cortex originally responsive to an arm become responsive to the face?
Definition
After loss of sensory input from the arm, the axons representing the arm degenerated leaving vacant synaptic sites, which the face axons sprouted to.

Or face axons were always there but they were overwhelmed by the normal arm input
Term
How chimps use of symbols differed from human language
Definition
- seldom arranged into new combinations (no productivity)
- seldom used them to describe anything (only requests were made)
- produced symbols better than they understood anyone else's use of symbols
Term
CCK
Definition
cholecstokinin...increases anxiety. Blocking CCK severly decreases anxiety, there are no drugs for this on the marker
Term
Thompson
Definition
presented rabbits with a tone and a puff of air to their eye
Term
Turnover
Definition
The amount of release and resynthesis of a neurotransmitter by a presynaptic neuron. You can infer the turnover rate by the level of 5-HIAA
Term
How do benzodiaphines work?
Definition
They bind to sites sensitive to GABA and helps the GABA to bind more tightly. This facilitates the effects of GABA and decreases anxiety.
Term
Habituation in Aplysia
Definition
Stops withdrawing gills. Depends on a change in the synapse between the sensory neuron and the motor neuron.
Term
Knudsen
Definition
put goggles on owls to shift their visual field. This also messed up their auditory field. A few days later, their auditory field also shifted. The owls reinterpreted audio cutes to match visual cutes. The visual system tunes up the auditory system.
Term
Symptoms of PTSD
Definition
- frequent distressing recollections (flashbacks)
- nightmares about the traumatic event
- avoidance of reminders of the event
- exaggerated arousal in response to noises and stimuli
Term
Tryptophan hydroxylase
Definition
the enzyme that converts tryptophan into serotnin.
Less of this enzyme = more likely to report frequent anger and aggression
Term
General adaptation syndrome
Definition
1) alarm - increased activity in sympathetic nervous system
2) resistance - cortisol secretion to raise alertness, fight infections, and heal
3)exhaustion - become tired, inactive and vulnerable because no energy left
Term
sensitization
Definition
an increase in response to mild stimuli as a result of previous exposure to more intense stimuli
Term
What happens during the startle reflex?
Definition
Auditory information (such as a loud noise) enters the cochlear nucleus in the medulla then goes to the pons, which command the bodies muscles to tense, especially in the neck
Term
Two places new neurons can form in humans
Definition
1) Olfactory receptors
2) Hippocampus
Term
Delayed response task
Definition
An animal sees an object then after a delay, it gets a choice between two objects and it must choose either the one that matches or does not match
Term
endozepines
Definition
anti-benzos. Increases fearfulness and aggression by blocking the effects of benzos and diazepam.
Term
specificity
Definition
if some of the synapses onto a cell have been highly active and others have not, only the active ones become strengthened (property of long term potentiation)
Term
cortisol
Definition
Term
cortisol
Definition
hormone that enables the body to maintain prolonged alertness, fight infections, and heal wounds
Term
ectoderm
Definition
layer of cells that becomes a tube with a seam
Term
cytokines
Definition
combats infections and also communicates with the brain to elicit appropriate behaviors. A
Term
ectoderm
Definition
layer of cells that becomes a tube with a seam
Term
cytokines
Definition
combat infections and also communicate with the brain to elicit appropriate behaviors.
Way of telling the brain that the body is ill.
Term
5 Steps for long term potentiation in hippocampus
Definition
1) Glutamate massively stimulates AMPA receptors
2) Depolarization enables glutamate to stimulate NMDA receptors nearby
3) which let Calcium enter the cell
4) Calcium creates changed in dendrites to future responses to glutamate
5) NMDA potentiates AMPA receptors and they revert to original condition
Term
Broca's Aphasia
Definition
Nonfluent aphasia. Inarticulate speech. Comprehension deficits when the meaning of a sentence depends on prepositions, conjunctions, word endings or has complex grammar.
Term
Apoptosis
Definition
death of cells if they do not make it to the proper postsynaptic cell by a certain age.
Term
working memory
Definition
the way we store information while we are working with it or attending to it
Term
retrograde transmitter
Definition
travels back to the presynaptic cell to modify it
Term
When does an epileptic attack occur?
Definition
When a population of neurons produce a sustained period of synchronous activity.
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