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Intro to anatomy & Physiology
Lecture Unit 5
34
Physiology
Not Applicable
04/24/2005

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Term
What is the general function of the digestive system?
Definition

It prepares food molecules for use in the body by the use of physical digestion and chemical digestion.

Term
What are the two general divisions of the digestive system and what organs comprise them?
Definition

Alimentary - mouth/oral cavity, pharynx, esophagus, stomach, small intestines, large intestines, rectum

Accessory Organs - salivary glands, liver, gall bladder, pancreas, teeth, tongue

Term
What parts of the alimentary canal secrete mucus and what are its functions?
Definition

Mucus is secreted by the lining of the entire alimentary canal.

Function is for lubrication and protection.

Term
Describe the functions and control mechanism of saliva.
Definition

Saliva lubricates food and starts the chemical digestion of carbohydrates.

Controlled by the nervous system.

Term
What are the digestive and absorptive functions of the mouth?
Definition

Mastrication - teeth are used for mechanical digestion

Chemical digestion - Salivary amylase converts carbohydrates into dextrins(shorter chained molecules.

Has very little absorption abilities.

Term
Describe the mechanism of swallowing.
Definition

Voluntary Stage - bolus is forced to the back of the oral cavity and into the oropharynx by the movement of the tongue upwards and backwards against the palate.

Pharygeal Stage - Controlled by the medulla - respiration inhibited - larynx raises and glottis closes - epiglottis closes off trachea - pharyngeal muscle contract forcing bolus into esophagus

Esophageal stage - (per'-is-STAL-sis; stalsis = constriction) Controlled by the medulla -Circular smooth muscle layer above bolus contracts forcing it down - longitudinal smooth muscle layer below bolus contracts widening the esophagus to accept the bolus - previous contractions occur in waves=peristalsis - gastroesophageal sphinter opens and bolus enter stomach - gastroesophageal sphincter closes

Term
What are the secretions of the stomach and their functions?
Definition

Hydrochloric Acid (HCI) - produced by parietal cells, it protects against pathogens and breaks food into smaller pieces.

Pepsin - produced by chief cells, it is an enzyme involved with digestion

Term
How are the stomach secretions controlled,(hint- 3 phases)?
Definition

Cephalic Phase- thought, taste, smell or sight of food stimulates increase in cerebral cortex/hypothalamus which stimulates increase in medulla oblongata which stimulates increase in gastric glands and gastric mobility

Gastric Phase
1 - Distention of stomach and increase in PH stimulates gastric gland(pyloric) endocrine glands - gastrin - stimulates gastric glands and gastric motility
2 - distention of stomach and increase in PH stimulates gastric glands and gastric motility

Intestinal Phase - turns gastric glands off
1 - Ditention of duodenum/presence of fatty acids - glucose stimulates duodenal endocrine glands - gastric inhibitory peptide (GIP), secretetin and cholecystokinin (CCK) decrease gastric glands and gastric motility
2 - Enterogastric reflex: distention of duodenum/presence of fatty acids glucose stimulates medulla oblongata decrease gastric glands and gastric motility

Term
What are the digestive and absorptive functions of the stomach? (3)
Definition

1. HCI - breaks food into smaller pieces.

2. Pepsin - converts proteins into proteoses and peptones, smaller chained molecules.

3. Very little absorption since only small molecules can be absorbed, water and alcohol

Term
Describe the different types of motility that occur in the stomach.
Definition

1. Receptive relaxation

2. Tonic contractions

3. Peristalsis

4. Control of gastric motility

Term
How are the stomach movements controlled?
Definition

1. Receptive relaxation - gastric muscles relax as food enters the stomach.

2. Tonic contractions - contractions of the longitudinal smooth muscle layer - mixes the chyme, stomach contents.

3. Peristalsis - moves chyme through the stomach.

4. Control of gastric motility - See previous for control of secretion.

Term
What cells of the pancreas produce pancreatic juice?
Definition

Acinar cells

Term
Describe the composition of the pancreatic juice.
Definition

Water, bicarbonate ion and digestive enzymes (trypsin, chymotrypsin, carboxypeptidase, pancreatic lipase, pancreatic nuclease and pancreatic amylase).

Term
How is the secretion of pancreatic juice controlled?
Definition

1. Sight, thought, taste, or smell of food stimulates medulla which stimulates pancreas.

2. Acids in duodenum stimulates duodenal endocrine glands, which stimulates hormones (secretin and CCK), which then stimulates pancreas.

Term
What is bile?
Definition

Bile = Water, bile salts and bile pigments, (gets its greenish color from this).

Term
How is bile release from the gall bladder controlled?
Definition

1. Bile is produced continuously and stored in the gall bladder.

2. CCK, secretin, gastrin and parasympathetic n.s. causes contraction of the gall bladder and the release of bile into the duodenum.

Term
What cells in the small intestine produce mucus?
Definition

Brunner's glands

Term
What cells in the small intestine produce digestive enzymes? List them and describe how their secretion is controlled.
Definition

Crypts of Lieberkuhn - produce two groups of enzymes erepsin and carbohdrases.

Control - mechanical/chemical stimulates small intestines which stimulates intestinal glands to produce erepsin and carbohdrases.

Term
Describe how carbohydrates are digested in the small intestines.
Definition

1. Dextrins converted to disaccharides by pancreatic amylase

2. Disaccharides converted to monosaccharides by carbohydrases

Term
Describe how proteins are digested in the small intestines.
Definition

1. Proteoses/ peptones converted to dipeptides by trypsin, chymotrypsin and carboxypeptidase

2. dipeptides converted to amino acids by erepsin

Term
Describe how lipids are digested in the small intestines.
Definition

1. Converted to emulsified fats (makes big blobs small blobs) by bile.

2. Emulsified fats converted to glycerol and fatty acids by pancreatic lipase.

Term
Describe how nucleic acids are digested in the small intestines.
Definition

Converted to nucleotides by pancreatic nuclease.

Term
How are monosaccharides, amino acids, nucleotides, absorbed in the small intestines?
Definition

They are actively absorbed, (by active transport).

Term
How are glycerol and fatty acids absorbed in the small intestines?
Definition

They are diffused into intestinal cells and combine to form fat which then diffuse out, become attached to proteins becoming chylomicron diffuse into lacteals - blood, (lymph capillaries).

Term
How are vitamins absorbed in the small intestines?
Definition

Vitamins diffuse into the blood, not digested at all.

Term
How are cations and anions absorbed in the small intestines?
Definition

Cations are actively absorbed

Anions diffuse into blood

Term
How is water absorbed in the small intestines?
Definition

Water moves into blood by osmosis.

Term
What are the four types of movement of the small intestines?
Definition

Segmenting

Pendular

peristalsis

gastroileal reflex

Term
Describe segmenting movement of the small intestines.
Definition

Segmenting movement - contractions of the circular muscle layer that segments and mixes the chyme.

Term
Describe pendular movement of the small intestines.
Definition

Pendular movement - contractions of the longitudinal smooth muscle layer that moves and mixes the chyme.

Term
Describe peristalsis movement of the small intestines.
Definition

Peristalsis - moves chyme through the intestines, like stomach and esophagus.

Term
Describe Gastroileal reflex movement of the small intestines.
Definition

Gastroileal reflex - ileum contracts moving contents into the large intestines.

Term
What substances are absorbed by the large intestines? (3)
Definition

1. Sodium - is actively absorbed

2. Water - is absorbed by osmosis

3. Vitamins, K, B12, thiamin and riboflavin - produced by bacteria in the gut

Term
Describe the five types of movement of the large intestine?
Definition

Segmenting - has to move at just the right rate, to fast = diarrhea to slow = constipation

Tonic contractions

Peristalsis

Mass movement - strong peristaltic wave that moves feces into the rectum

Defecation - Rectum stretches as it fills, stimulates stretch receptors, peristalsis, contraction of rectal muscles and relaxation of internal sphinter, cerebral cortex, relaxation of external sphincter and contraction of diaphragm.

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