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Intravenous Drugs, Pumps & Antidotes
Intravenous Drugs, Pumps & Antidotes
30
Pharmacology
Professional
09/19/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
Why is intravenous therapy, or IV therapy, commonly referred to as a "drip".
Definition

Many systems of administration employ a drip chamber, which prevents air entering the blood stream (air embolism) and allows an estimate of flow rate.

Term
Can TPN be administered via IV?
Definition
Yes.
Term
There are two types of intravenous line, what are they?
Definition
peripheral IV and a central IV line
Term
A peripheral IV line consists of?
Definition

short catheter (a few centimeters long) inserted through the skin into a peripheral vein (any vein that is not inside the chest of abdomen), usually in the hand or arm

 

Term
What does a Central IV line consists of?
Definition

They flow through a catheter with its tip placed in a large vein (e.g. subclavian, internal jugular, inferior vena cava)

Term
What are the advantages of a central IV line over a peripheral line?
Definition

It can deliver fluids/medications that are overly irritating to peripheral veins (eg. some chemo drugs, TPN, higher concentrations of potassium)

 

They can contain multiple parallel compartments (or lumens) within the catheter so multiple medications can be given at once even if they would not be chemically compatible within a single catheter

 

Can measure central venous pressure and other hemodynamics (cardiac output, etc.) through a central line

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Term
Name some disadvantages of central IV lines
Definition

higher risk of bleeding, infection, and thromboembolism and they are more difficult to insert correctly (require expertise and may be placed by a physician or trained staff if a PICC)

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Term
Name a commonly used central line?
Definition
peripherally inserted (central catheter, or PICC line)
Term
When is a PICC line needed?
Definition

PICC lines are used when access to the vein is required for a prolonged period of time or when infused substance would damage a peripheral IV line

Term
Where are PICC normally inserted?
Definition

The line is inserted into a peripheral vein, typically in the upper arm, and advanced until the catheter tip terminates in a larger vein in the chest near the heart to obtain intravenous access

Term
Intravenous medication require the use of what for administration?
Definition
infusion pump
Term
What is a "smart pump"
Definition

Smart IV infusion pumps have drug libraries with standardized concentrations for commonly used drugs, which allow them to provide point - of -care decision support feedback for excessively high or low rates and doses. These devices may be programmed to provide "soft" alerts that cannot be overridden. These have been shown to reduce medication errors

 

 

Term
Name inotropes given IV?
Definition

Dobutamine

Milrinone

 

Term
Name vasopressors given IV
Definition

Dopamine

Epinephrine

Norepinephrine

Phenylephrine

Term
How does dobutamine work?
Definition
primarily B1 agonist causing increased contractility and heart rate
Term
how does milrinone work?
Definition

selective phosphodiesterase inhibitor in cardica and vascular tissue, resulting in vasodilation and inotropic effects with little chronotropic effects

Term
How does dopamine work?
Definition

endogenous precursor of norepinephrine (NE) that stimulates different receptors at different doses

Term
[image]
Definition
Statement. Not a question.
Term
What is extravasation?
Definition

Extravasation: leakage of I.V. into surrounding tissue

 

Extravasation of vasopressors/inotropes can cause tissue damage and necrosis

Term
How to treat extravasation with vasopressors?
Definition

phentolamine (Regitine), an α - adrenergic blocker that antagonizes the effects of vasopressors.

 

Dilute 5-10 mg of phentolamine in 10ml of NS and give SC to infiltrated area.

Term
Name vasodilators that are given IV?
Definition

Nitroglycerin

Sodium Nitroprusside (Nipride)

Term
Sodium Nitroprusside is very sensitive to?
Definition
light; wrap in aluminum foil to protect from light
Term
[image]
Definition
Statement. Not a question.
Term
Name some other drugs that are given IV (vague question, I know)
Definition

[image]

 

[image]

Term
What is the go-to source for IV compatibilities?
Definition
Trissel's Handbook on Injectable Drugs
Term
Define instability?
Definition

occurs when a product/solution is modified because of storage conditions (i.e. time, temperature, light, absorption). A product is considered unstable when it loses more than 10% of its labeled potency from the time of preparation

Term
Define Incompatibility?
Definition

Incompatibility: occurs when one product is mixed/combined with another and changes occur that make the product unsuitable for patient use (i.e. degradation, precipitation, a change in pH &c.)

Term
Name common IV admixtures that are not compatible!
Definition
[image]
Term
To reduce the potential for errors, smart pumps should possess what?
Definition
bar-code functionality
Term
Smart pump limitations?
Definition

If the smart pump drug library is bypasses, and the infusion rate and volume is manually entered, the dose error reduction software will not be in place to prevent a potential error.

 

The software also cannot replace independent double checks

 

And independent double check is warranted for certain identified high alert medications

 

Too many concentration options for each drug increase the potential for the wrong concentration to be selected

 

Soft stop alerts can be easily overrideen

 

Consistent monitoring and support for process change is required

 

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