Term
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Definition
undersurface of the diaphragm to the floor of the pelvis containing the stomach, small intestine, large intestine, liver, gallbladder, and spleen |
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Term
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Definition
duodenum, pancreas, kidneys, adrenal glands, great vessels (aorta and vena cava), and most mesenteric vascular structures |
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Term
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Definition
k.a. spontaneous bacterial peritonitis (SBP); inflammation of the peritoneum by an extraperitoneal source, frequently occurring from hematogenous dissemination; no evident source |
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Term
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Definition
inflammation or mechanical break of the integrity of the intestinal or the urogenital tract or solid organs, thus exposing the peritoneal cavity to the resident GIT flora (e.g. acute peritonitis via perforation, postoperative peritonitis, or post-‐traumatic peritonitis) |
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Term
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Definition
associated with highest morbidity and mortality; persistent or recurrent 48 hrs after intra-‐abdominal infection, after initial treatment of a primary or secondary peritonitis |
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Term
Primary peritonitis Microbiology |
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Definition
often always a monomicrobial infection caused by enteric gram negative rods |
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Term
Secondary and tertiary peritonitis Microbiology |
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Definition
often a polymicrobial infection caused by enteric gram negative rods and anaerobes |
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Definition
E coli
Escherichia coli Klebsiella species Pseudomonas aeruginosa 14 Proteus mirabilis Enterobacter species |
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Term
Community-‐Acquired Empiric Combination Therapy Mild-‐Moderate |
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Definition
1st generation: Cefazolin (IV) 2nd generation: Cefuroxime (IV/PO) 3rd generation: Ceftriaxone (IV), Cefotaxime (IV) -‐Plus-‐ Metronidazole (IV/PO) Ciprofloxacin (IV/PO), Levofloxacin (IV/PO) -‐Plus-‐ Metronidazole (IV/PO) |
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Term
Community-‐Acquired Empiric Combination Therapy Severe |
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Definition
3rd generation: Ceftazidime (IV) 4th generation: Cefepime (IV) -‐Plus-‐ Metronidazole (IV/PO) Ciprofloxacin (IV/PO), Levofloxacin (IV/PO) -‐Plus-‐ Metronidazole (IV/PO) Gentamicin (IV), Tobramycin (IV), Amikacin (IV) -‐Plus-‐ Metronidazole (IV/PO) or Clindamycin$(IV/PO) Aztreonam (IV)δ -‐Plus-‐ Metronidazole (IV/PO) |
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Term
Community Acquired Empiric Monotherapy Mild-‐Moderate |
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Definition
Amoxicillin/Clavulanate (PO)* Ampicillin/Sulbactam (IV/PO)* Ticarcillin/Clavulanate (IV) 2nd generation: Cefoxitin (IV)γ Moxifloxicin (IV/PO) Ertapenem (IV) Tigecycline∝ (IV) |
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Term
Community Acquired Empiric Monotherapy Severe |
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Definition
Piperacillin/Tazobactam (IV) -‐ -‐ Imipenem/Cilastatin (IV) Doripenem (IV) Meropenem (IV) -‐ Aztreonam (IV)δ -‐Plus-‐ Metronidazole (IV/PO) |
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Definition
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