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Interstitial Lung Diseases
Downstate > MS2 Respiratory Block > Interstitial Lung Diseases
42
Medical
Graduate
02/09/2011

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Cards

Term
tx for posterior uveitis vs. anterior uveitis in sarcoidosis
Definition
posterior: systemic steroids; anterior: topical steroids
Term
what defines each stage in sarcoidosis?
Definition
1. hilar adenopathy, no lung involvement; 2. hilar adenopathy+lung involvement; 3. no adenopathy, lung involvement; 4. fibrosis
Term
immune profile in a pt with sarcoidosis
Definition
Th1>Th2, anergy, oligoclonal CD4 T cells, polyclonal hypergammaglobulinemia
Term
organs involved in sarcoidosis
Definition
lung, skin (nodules, plaques, scales), eyes (iritis, uveitis), spleen (-megaly), bone marrow
Term
noncaseating granulomas, TB culture negative, no nephropathy, pANCA-, cANCA-, no eosinophilia,
Definition
sarcoidosis
Term
child presents with dry airways, dry and persistent cough, Sjogren's; dx?
Definition
LIP
Term
pANCA+, eosinophilia; dx?
Definition
Churg-Strauss
Term
cANCA+, saddle-nose deformity, glomerulonephritis, pulmonary granulomas; dx?
Definition
Wegener's
Term
HRCT: nodules next to thin-walled cysts; dx?
Definition
PLCH
Term
stellate nodules, spares CVA; dx?
Definition
PLCH
Term
ILD more common in smokers
Definition
PLCH, DIP
Term
defect in sphingomyelinases
Definition
Niemann-Pick
Term
defect in cerebrosidase
Definition
Gaucher's
Term
granulomatous colitis, ILD
Definition
Hermansky-Pudlak
Term
DAH, glomerulonephritis; dx?
Definition
Goodpasture's
Term
female with pneumothorax; HRCT: thin-walled cysts surrounded by normal lung; dx?
Definition
LAM
Term
elevated LDH, polycythemia, hypergammaglobulinemia
Definition
PAP
Term
leukemic pt with "bat-wing" CXR; dx?
Definition
PAP
Term
HRCT: crazy paving
Definition
PAP
Term
migratory opacities
Definition
BOOP or COP
Term
pregnant female with UTI presents with hypersensitivity pneumonitis; what drug is she taking?
Definition
nitrofurantoin
Term
pt with hx of Hodgkin's lymphoma presents with interstitial lung disease; what drug is responsible?
Definition
bleomycin or carmustine
Term
pt with hx of atrial fibrillations is worked up for ILD. HRCT shows an image as if contrast was given but it was not; what drug is responsible?
Definition
amiodarone
Term
anti-Jo-1 antibody+
Definition
DM/PM
Term
SLE+acute pneumonitis ->
Definition
DAH
Term
pleuritis +/- effusion, anti-dsDNA+; dx?
Definition
SLE+ILD
Term
RA, necrobiotic nodules, pneumoconiosis; dx?
Definition
Caplan's triad -> RA+ILD
Term
presentation of RA+ILD
Definition
male coal miner with pleuritis +/- effusion, necrobiotic nodules +/- cavitations, Caplan's syndrome
Term
markers for scleroderma
Definition
Scl-70
Term
HRCT: bilateral, subpleural ground glass opacities without honeycombing; dx?
Definition
NSIP
Term
HRCT: bilateral, patchy ground glass or consolidation. Biopsy: hyaline membranes; dx?
Definition
AIP (Hamman-Rich)
Term
clinical presentation of AIP
Definition
2 weeks of prodrome illness then dry cough, fever, dyspnea, then hypoxemia and respiratory failure
Term
macrophages in alveolar space with little interstitial fibrosis
Definition
DIP
Term
what would you find on a HRCT in a pt with IPF?
Definition
patchy, basilar subpleural reticular opacities, traction bronchiectasis, honeycombing
Term
what would you find on a lung biopsy in a pt with IPF?
Definition
fibrotic foci, heterogenous at subpleural parenchyma
Term
where can BAL be used to diagnose and confirm? (4)
Definition
sarcoidosis, hypersensitivity pneumonitis, PAP, DAH, cancer
Term
elevated ACE
Definition
sarcoidosis
Term
precipitins
Definition
hypersensitivity pneumonitis
Term
eosinophilic pneumonitis, hypersensitivity pneumonitis are [acute/subacute/chronic/episodic]
Definition
acute
Term
sarcoidosis, drug, CTD, COP are [acute/subacute/chronic/episodic]
Definition
subacute
Term
sarcoidosis, CTD, IPF, PLCH, pneumoconiosis is [acute/subacute/chronic/episodic]
Definition
chronic
Term
characteristics of impaired repair
Definition
fibrin, fibroblasts, myofibroblasts, type II cells replace type I cells, new blood vessels, more ECM, reduced surface area
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