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indirect bili = hemolysis |
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overall best marker for severity of liver dz |
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#1 cause of indirect hyperbilirubinemia |
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Definition
GIlbert's syndrome; lack the enzyme that conjugates bilirubin |
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#1 cause of fulminant hepatic failure |
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renal failure in the setting of hepatic dz; |
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low urine Na+ normal urine Osm |
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terlipressin 0.5mg IV + albumin = first line tx of confirmed HRS. HyoVolemia must be ruled out; renal failure remains> giving bolus IVF. Also must r/o sepsis with Bcx and start imperic tx with abx that aren't cleared through kidey; ceftriaxone |
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how might heart failure cause elevated LFTs |
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Definition
right sided heart failure can cause congesetion in liver |
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hepatic vein thrombosis (women on contraceptives) |
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fever and jaundice > heavy drinking |
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tx for esophageal varicies |
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middle aged itching female with HLD, >DBil, >ALP/GGT, anti-mitochondrial ab |
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subq bruising around the umbilicus from where blood in necrotizng pancreatitis travels down the falciform ligament to the umbilicus |
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elevated amylase/lipase one week after resolution of pancreatitis = |
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pancreatic calcifications, malabsorption and insulin dependent DM |
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chronic pancreatitis - EtOH |
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what is likely source of recurrent salmonella sepsis? |
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Describe the pathophysiology of hepatorenal syndrome |
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kidneys are functional but are failing under current conditions of cirrhosis; likely 2/2 vasc changes supplying the kidneys resulting in < blood flow to kidneys. Tx = pressors and albumin |
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