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Internal Med Exam
internal med exam
30
Medical
Professional
10/25/2011

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Cards

Term
FE Na formula
Definition
(urine Na * plasma Cr) / (Serum Na * urine Cr)
Term
FENa interpretation
greater than 1%
Less than 1%
Definition
<1% is pre renal Dx
>1% can be several things such as ATN
Term
FEUrea formula
Definition
(urine Urea * plasma Cr) / (Serum Urea * urine Cr)
Term
FE Urea interpretation

cutoffs and significances
Definition
<35% = pre renal azotemia

>35% = normal
Term
Normal body Osm
Definition
275 to 295 osm
Term
causes of hypernatremia - the 6 Ds
Definition
Diuretics
Dehydration
Diabetes insipidus
Docs (iatrogenic)
Diarrhea (and vomiting)
Disease of kidney (hyperalDOSTERONE)
Term
1) Rate of change in treating hyponatremia

2) Rate of change in treating hypernatremia
Definition
1) asymptomatic: max 0.5 meq/L/hr
symptomatic rapid 1.0 meq/L/hr to Sx resolve
TOTAL max 8-10meq/L/day or else pontine myelinolysis

2) 0.5 meq/L/hr and max 12 meq/L/day or brain hernia
Term
FENa interpretation
greater than 1%
Less than 1%
Definition
<1% is pre renal Dx
>1% can be several things such as ATN
Term
FEUrea formula
Definition
(urine Urea * plasma Cr) / (Serum Urea * urine Cr)
Term
FE Urea interpretation

cutoffs and significances
Definition
<35% = pre renal azotemia

>35% = normal
Term
Normal body Osm
Definition
275 to 295 osm
Term
Total body water deficit formula
Definition
(body Kg * 0.6) * ((serm Na / 140) -1)
Term
causes of hypernatremia - the 6 Ds
Definition
Diuretics
Dehydration
Diabetes insipidus
Docs (iatrogenic)
Diarrhea (and vomiting)
Disease of kidney (hyperalDOSTERONE)
Term
1) Rate of change in treating hyponatremia

2) Rate of change in treating hypernatremia
Definition
1) asymptomatic: max 0.5 meq/L/hr
symptomatic rapid 1.0 meq/L/hr to Sx resolve
TOTAL max 8-10meq/L/day or else pontine myelinolysis

2) 0.5 meq/L/hr and max 12 meq/L/day or brain hernia
Term
#1 most common cause for upper GI bleed
Definition
Peptic ulcer disease 40-79% of the time.
Most commonly due to H. pylori, then also NSAID, EtOH, and smoking
Term
BUN/Cr ratio expected range in upper GI bleed
Definition
35:1 or greater (blood digestion or prerenal due to vol loss - not sure which is the cause)
Term
TRUE/FALSE:
a PPI and H2 block can be co administered w/o consequence
Definition
FALSE - they will negate eachother = no effect.
Term
Anion gap formula and normals
Definition
AG = Na -(Cl + HCO3)

normal is 12, greater is an anion gap acidosis
Term
normal pH,
pCO2
pO2
HCO3
Cl
Na
K
Definition
pH is 7.4 +- .02
pCO2 is 40 +-2.0
pO2 is 80-100
HCO3 is 24 +-1
Cl is 98 - 106
Na is 140 +-5
K is 3.5 - 5.0
Term
what is WINTER'S FORMULA for expected pCO2 in setting of metabolic acidosis
Definition
expected pCO2 = 1.5(bicarb) +8 +-2
Term
In respiratory acidosis/alkalosis acute and chronic what are the appropriate HCO3 compensations per 10mmHg of pCO2?

Also change in pH acute vs chronic per 10 pCO2 change.
Definition
alkalosis is increase pCO2 -acute is 1meq bicarb up, chronic is 3 meq bicarb up
Acidosis is decrease pCO2 - acute is 2meq bicarb down, chronic is 4meq bicarb down

pH change: acute is +-0.08 per 10 pCO2
chronic is +- 0.03 per 10 pCO2
Term
potential bicarb formula and interpretation
Definition
(delta AG) +bicarb = potential bicarb
(AG -12) + HCO3 (from lytes) is potential bicarb
normal is 24, pot. bicarb less than 24 is NAG metab acidosis
greater than 24 is metabolic alkalosis
Term
3 most common culprits of alveolar/lobar community acquired pneumonia
Definition
Strep pneumonia
H. influenzae
Moraxella cattarrharhiahahidihthrriahras or whatever the last part is
Term
3 atypical pneumonias - community acquired
Definition
chlamidia pneumo
legionella
mycoplasma
Term
Light's criteria of exudate vs transudate in pleural effusion
Definition
1) if )effusion protein) / (sera protein) = >0.5 is exudate
2) effusion LDH / sera LDH = >0.6 is exudate
3) effusion LDH > (2/3 upper lim normal sera LDH)
Term
empyema characteristics
Definition
frank pus / cloudy fluid
pH <7.20 ***** most sensitive*****
glucose <60
high protein, high LDH,
positive gram stain/culture, leukocytosis
Term
Tx comm acquired pneumonia out and inpatient, not ICU
Definition
*** OUTPATIENT: macrolide OR doxy OR moxi or levo
*** INPATIENT: Beta lac-(gen3 ceph OR augmentin) & macrolide /// OR just antipneumo flouroquinolone moxi levo
Term
Tx ICU patient w/ comm acquire pneumonia
Definition
(beta lac of gen3 cepalo OR ampiciilin/sulbctm)
AND (Macrolide or antipneumo floroquinolone moxi-levo)

ADD if structure change think pseudomonads: (pip/tazo, meropenem, gen4 ceph) AND (antipseud floroquinolone cipro or levoflox)

ADD if MRSA vanco or lenizolid
Term
NOSOCOMIAL pneumonia Tx
Definition
(antipseudo penicillin pip tazo OR gen3 cephalo) AND
(antipseudo aminoglycoside OR floroquinolone)

ADD if legionarres macrolide
ADD if MRSA vanco or linezolid
Term
Tx aspiration pneumonia
Definition
gram - coverage: clindamycin
OR (augment/amox-clavulonate AND metronidazole)
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