Term
Complex organ weighing an average 4kg covering an area sq m. |
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Protects against harmful agents, microorganisms, physical, ultraviolet light. Regulates temperature and also plays a role in immune regulation through skin associated lymphoid tissue |
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epidermis consists of 4 layers from surface to base |
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Definition
Stratum corneum, stratum granulosum, stratum spinosum, and basal layer |
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4 cell types found in the epidermis |
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Definition
keratinocytes, basal cells, melanocytes, Langerhan cells |
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Between the epidermis and dermis |
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tough, elastic support, contains blood vessels, nerves and skin appendages |
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sweat glands, hair follicles, sebaceous glands |
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lies between the dermis and fascia. insulates the body, cushions deep tissues from blunt trauma |
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which cell makes up the majority of epidermal cells |
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source of cytokines that regulate cutaneous environment |
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produce melanin pigment to screen uv light |
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dendritic cells they are APCs to immune system |
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part of skin which is used for cooling |
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Verrucae is an epidermal hyperplasia caused by |
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Direct contact, or autoninoculation |
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common wart, occur anywhere on the skin but mostly on the dorsum of the hand and fingers. Gray white papules |
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Definition
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flat wart, smooth slightly elevated papules, often occurs on face |
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Definition
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Scaly lesions 1-2 cm on soles and palms respectively |
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Definition
verruca plantaris and verruca palmaris |
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Term
soft, tan, cauliflower like papillomas on genitalia and perianal areas |
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Definition
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Term
Morphology of conyloma accuminatum |
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Definition
1. Koilocytosis (cytoplasmic vacuolization) of superficial keratinocytes 2. Acanthosis, hyperkeratosis, and parakeratosis 3. viral particles within nuclei |
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Term
types 6 and 11 warts cause |
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Papular skin lesions transmitted by direct contact in children and sexual active adults |
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multiple pink umbilicated papules on skin and mucous membranes; cheesy material can be expressed from cup- like central umbilications |
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cup like hyperplasia of epidermal cells with large homogenous ellipsoid eosinophilic cytoplasmic inclusions. |
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Superficial skin infection caused by staph and strep usually on face and hands |
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Erythematous macule - pustule - brk down to form crusts |
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pustules contain neutrophils and gram + cocci |
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Pus filled nodule in DERMIS usually caused by S. aureaus, ruptures through epidermis |
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necrotizing infection of skin and subcutaneous tissue, composed of furuncles and also deeper |
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Erythematous swelling of the skin mainly caused by S. pyogenes. Common in warm climates |
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acute spreading infection of loose CT of deep layers of dermis. Usually through tramatic inoculation |
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Superficial fungal infections are confined to what layer of epidermis |
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erythematous sealing and maceration btw and underneath toes |
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Definition
Tinea pedis (athlete's foot) |
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dermatophytosis of nail of fingers and toes causing deformity of nail plate |
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Infection of scalp, affecting hair which tends to brk off. |
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Infection of bearded regions |
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Infection of body, especially in children, expanding erythematous plaque with elevated scaling border |
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Infection by malassezia furfur, affects trunk producing hyper-hypo macules with peripheral scaling (NICK) |
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a contagious skin caused by itch mites, burrows into stratum corneum mainly into skin of palms, wrist, scrotal folds, and periareolar skin. Intense itching and eczema |
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Infestation of lice usually on scalp or pubic area. May cause impetigo and cervical lymphadenopathy |
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Dermal perivascular infiltration with lymphocytes, eosinophils, and histiocytes |
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Definition
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With this disease almost all patients develop some sorts of skin disease |
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Microscopic appearance of intranuclear and intracytoplasmic nuclear inclusions, ulceration and intraepidermal acantholytic vessicles |
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Occorence of this in an otherwise healthy person under age 60 is strong evidence of AIDS |
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other skin pathologies of AIDS |
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Definition
Purpura, pigmentation, major oral apththae |
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Term
HSV, scabies, deep mycoses, candidosis are found in |
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