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Integumentary System
medical terminology--the skin
170
Physiology
Professional
02/01/2012

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Term
adip/o, lip/o, steat/o
Definition
fat
Term
derm/o, dermat/o, cutane/o
Definition
skin
Term
erythr/o
Definition
red
Term
hidr/o
Definition
sweat
Term
hist/o, histi/o
Definition
tissue
Term
kerat/o
Definition
hard
Term
leuk/o
Definition
white
Term
melan/o
Definition
black
Term
myc/o
Definition
fungus
Term
onych/o
Definition
nail
Term
plas/o
Definition
formation
Term
purpur/o
Definition
purple
Term
scler/o
Definition
hard
Term
seb/o
Definition
sebum (oil)
Term
squam/o
Definition
scale
Term
trich/o
Definition
hair
Term
xanth/o
Definition
yellow
Term
xer/o
Definition
dry
Term
integument
Definition
skin
Term
epithelium
Definition
cells covering external and internal surfaces of the body
Term
epidermis
Definition
thin outer layer of the skin
Term
squamous cell layer
Definition
flat, scale-like epithelial cells comprising the outermost epidermis
Term
basal layer
Definition
deepest layer of epidermis
Term
melanocyte
Definition
cell in the basal layer that gives color to the skin
Term
melanin
Definition
dark brown to black pigment contained in melanocytes
Term
dermis
Definition
dense, fibrous connective tissue layer of the skin, also known as corium
Term
sebaceous glands
Definition
oil glands in the skin
Term
sebum
Definition
oily substance secreted by the sebaceous glands
Term
sudoriferous glands
Definition
sweat glands (sudor=sweat; ferre=to bear)
Term
subcutaneous layer
Definition
connective and adipose tissue layer just under the dermis
Term
collagen
Definition
protein substance in skin and connective tissue (koila=glue; gen=producing)
Term
hair
Definition
outgrowth of the skin composed of keratin
Term
nail
Definition
outgrowth of the skin, composed of keratin, at the end of each finger and toe
Term
keratin
Definition
hard protein material found in the epidermis, hair, and nails
Term
lesion
Definition
an area of pathologically altered tissue; the two types of lesions are primary and secondary
Term
primary lesions
Definition
lesions arising from previously normal skin
Term
macule or macula
Definition
a flat, discolored spot on the skin up to 1 cm across (ex. a freckle)
Term
patch
Definition
a flat, discolored area on the skin larger than 1 cm (ex. vitiligo)
Term
papule
Definition
a solid mass on the skin up to 0.5 cm in diameter (ex. a mole)
Term
plaque
Definition
a solid mass greater than 1 cm in diameter and limited to the surface of the skin
Term
nodule
Definition
a solid mass greater than 1 cm that extends deeper into the epidermis
Term
tumor
Definition
a solid mass larger than 1-2 cm
Term
wheal
Definition
an area of localized skin edema (swelling)--ex. a hive
Term
vesicle
Definition
little bladder; an elevated, fluid-filled sac (blister) within or under the epidermis up to 0.5 cm in diameter (ex. a fever blister)
Term
bulla
Definition
a blister larger than 0.5 cm (ex. a second-degree burn)
bulla=bubble
Term
pustule
Definition
a pus-filled sac (ex. a pimple)
Term
secondary lesions
Definition
lesions that result in changes in primary lesions
Term
erosion
Definition
gnawed away; loss of superficial epidermis, leaving an area of moisture but no bleeding (ex. area of moisture after rupture of a vesicle)
Term
ulcer
Definition
an open sore on the skin or mucous membrane that can bleed and scar; sometimes accompanied by infection (ex. decubitus ulcer)
Term
excoriation
Definition
a scratch mark
Term
fissure
Definition
a linear crack in the skin
Term
scale
Definition
a thin flake of exfoliated epidermis (ex. dandruff)
Term
crust
Definition
a dried residue of serum (body liquid), pus, or blood on the skin (ex. as in impetigo)
Term
vascular lesions
Definition
lesions of a blood vessel
Term
cherry angioma
Definition
a small, round, bright red blood vessel tumor on the skin, often on the trunk of the elderly
Term
telangiectasia or spider angioma
Definition
a tiny, red blood vessel lesion formed by the dilation of a group of blood vessels radiating from a central arteriole, most commonly on the face, neck, or chest (telos=end)
Term
purpuric lesions
Definition
purpura; lesions resulting from hemorrhages into the skin
Term
petechia
Definition
spot; reddish-brown, minute hemorrhagic spots on the skin that indicate a bleeding tendency; a small purpura
Term
ecchymosis
Definition
bruise; a black and blue mark; a large purpura (chymo=juice)
Term
cicatrix of the skin
Definition
a mark left by the healing of a sore or wound, showing the replacement of destroyed tissue by fibrous tissue (cicatrix=scar)
Term
keloid
Definition
an abnormal overgrowth of scar tissue that is thick and irregular (kele=tumor)
Term
epidermal tumors
Definition
skin tumors arising from the epidermis
Term
nevus
Definition
a congenital malformation on the skin that can be epidermal or vascular; also called a mole
Term
dysplastic nevus
Definition
a mole with precancerous changes
Term
verruca
Definition
an epidermal tumor caused by a papilloma virus, also called a wart
Term
alopecia
Definition
baldness; natural or unnatural deficiency of hair
Term
comedo (pl. comedos, comedones)
Definition
a plug of sebum (oil) within the opening of a hair follicle
Term
closed comedo
Definition
a comedo below the skin surface, with a white center (whitehead)
Term
open comedo
Definition
a comedo open to the skin surface, with a black center caused by the presence of melanin exposed to air (blackhead)
Term
eruption
Definition
appearance of a skin lesion
Term
erythema
Definition
redness of skin
Term
pruritus
Definition
severe itching
Term
rash
Definition
a general term for skin eruption, most often associated with communicable disease
Term
skin pigmentation
Definition
skin color resulting from the presence of melanin
Term
depigmentation
Definition
loss of melanin pigment in the skin
Term
hypopigmentation
Definition
areas of skin lacking color because of deficient amounts of melanin
Term
hyperpigmentation
Definition
darkened areas of skin caused by excessive amounts of melanin
Term
suppuration
Definition
production of purulent matter (pus)
Term
urticaria
Definition
hives; an eruption of wheals on the skin accompanied by itching (urtica=stinging nettle)
Term
xeroderma
Definition
dry skin
Term
acne
Definition
inflammation of the sebaceous glands and hair follicles of the skin, evidenced by comedones (blackheads), pustules, or nodules on the skin (acne=point)
Term
albinism
Definition
a hereditary condition characterized by a partial or total lack of melanin pigment (particularly in the eyes, skin, and hair)
Term
burn
Definition
injury to body tissue caused by heat, chemicals, electricity, radiation, or gases
Term
first-degree burn
Definition
a burn involving only the epidermis; characterized by erythema (redness) and hyperesthesia (excessive sensation)
Term
second-degree burn
Definition
a burn involving the epidermis and ther dermis; characterized by erythema, hyperesthesia, and vesications (blisters)
Term
third-degree burn
Definition
a burn involving all layers of the skin; characterized by the destruction of the epidermis and dermis, with damage or destruction of subcutaneous tissue
Term
dermatitis
Definition
inflammation of the skin characterized by erythema, pruritus (itching), and various lesions
Term
dermatosis
Definition
any disorder of the skin
Term
exanthematous viral disease
Definition
an eruption of the skin caused by a viral disease (exanthema=eruption)
Term
rubella
Definition
reddish; German measles
Term
rubeola
Definition
reddish; 14-day measles
Term
varicella
Definition
a tiny spot; chickenpox
Term
eczema
Definition
to boil out; often used interchangeably with dermatitis to denote a skin condition characterized by the appearance of inflamed, swollen papules and vesicles that crust and scale, often with sensations of itching and burning
Term
furuncle
Definition
boil; a painful nodule formed in the skin by inflammation originating in a hair follicle; caused by staphylococcosis
Term
carbuncle
Definition
a skin infection consisting of clusters of furuncles (carbo=small, glowing embers)
Term
abscess
Definition
a localized collection of pus in a cavity formed by the inflammation of surrounding tissues, which heals when drained or excised (abcessus=a going away)
Term
gangrene
Definition
an eating sore; death of tissue associated with loss of blood supply
Term
herpes simplex virus type 1 (HSV-1)
Definition
transient viral vesicles (ex. cold sores or fever blisters) that infect the facial area, especially the mouth and nose (herpes=creeping skin disease)
Term
herpes simplex virus type 2 (HSV-2)
Definition
sexually transmitted, ulcer-like lesions of the genital and anorectal skin and mucosa; after initial infection, the virus lies dormant in the nerve cell root and may recur at times of stress
Term
herpes zoster
Definition
a viral disease affecting the peripheral nerves characterized by painful blisters that spread over the skin following affected nerves, usually unilateral; also known as shingles (zoster=girdle)
Term
impetigo
Definition
a highly contagious, bacterial skin inflammation marked by pustules that rupture and become crusted, most often around the mouth and nostrils
Term
keratoses
Definition
thickened areas of epidermis
Term
actinic (or solar) keratoses
Definition
localized thickening of the skin caused by excessive exposure to sunlight, a known precursor to cancer
Term
seborrheic keratoses
Definition
benign, wart-like tumors; more common on elderly skin
Term
lupus
Definition
a chronic autoimmune disease characterized by inflammation of various parts of the body
Term
cutaneous lupus
Definition
limited to the skin; evidenced by a characteristic rash, especially on the face, neck, and scalp
Term
systemic lupus erythematosus (SLE)
Definition
a more severe form of lupus involving the skin, joints, and often vital organs (ex. lungs or kidneys)
Term
malignant cutaneous neoplasm
Definition
skin cancer
Term
squamous cell carcinoma (SCC)
Definition
malignant tumor of the squamous epithelium
Term
basal cell carcinoma (BCC)
Definition
malignant tumor of the basal layer of the epidermis; the most common type of skin cancer
Term
malignant melanoma
Definition
malignant tumor composed of melanocytes
Term
Kaposi sarcoma
Definition
malignant tumor of the walls of blood vessels, appearing as painless, dark bluish-purple plaques on the skin; often spreads to the lymph nodes and internal organs; commonly seen in patients with HIV/AIDS
Term
onychia
Definition
inflammation of the fingernail or toenail
Term
paronychia
Definition
inflammation of the nail fold
Term
pediculosis
Definition
infestation with lice that causes itching and dermatitis
Term
pediculosis capitis
Definition
head lice
Term
pediculosis pubis
Definition
lice that generally infect the pubic region and sometimes also hair of the axilla, eyebrows, eyelashes, beard, or other hairy body surfaces; also called crabs
Term
psoriasis
Definition
itching; a chronic, recurrent skin disease marked by silvery scales covering red patches, papules, and or plaques on the skin that result from overproduction and thickening of skin cells; common sites of involvement are the elbows, knees, genitals, arms, legs, scalp and nails
Term
scabies
Definition
a contagious disease caused by a parasite (mite) that invades the skin, causing an intense itch, most often at articulations between the fingers or toes, elbow, etc.
Term
seborrhea
Definition
a skin condition marked by the hypersecretion of sebum from the sebaceous glands
Term
tinea
Definition
a group of fungal skin diseases identified by the body part affected, including tinea corporis (body), commonly called ringworm, and tinea pedis (foot), also called athlete's foot
Term
vitiligo
Definition
a condition caused by the destruction of melanin that results in the appearance of white patches on the skin (commonly the face, hands, legs, and genital areas)
Term
biopsy (Bx)
Definition
removal of a small piece of tisue for microscopic pathologic examination
Term
biopsy
Definition
Bx
Term
excisional biopsy
Definition
removal of an entire lesion
Term
incisional biopsy
Definition
removal of a selected portion of a lesion
Term
shave biopsy
Definition
a technique using a surgical blade to "shave" tissue from the epidermis and upper dermis
Term
culture and sensitivity
Definition
C&S
Term
culture and sensitivity (C&S)
Definition
a technique of isolating and growing colonies of microorganisms to identify a pathogen and to determine which drugs might be effective for combating the infection it has caused
Term
frozen section
Definition
FS
Term
frozen section (FS)
Definition
a surgical technique that involves cutting a thin piece of tissue from a frozen specimen for immediate pathologic examination
Term
skin tests
Definition
methods for determining the reaction of the body to a given substance by applying it to, or injecting it into, the skin; commonly used in treating allergies
Term
scratch test
Definition
a test in which a substance is applied to the skin through a scratch
Term
patch test
Definition
a test in which a substance is applied topically to the skin on a small piece of blotting paper or wet cloth
Term
chemosurgery
Definition
removal of tissue after it has been destroyed by chemical means
Term
chemical peel
Definition
a technique for restoring wrinkled, scarred, or blemished skin by applying an acid solution to "peel" away the top layers of the skin
Term
cryosurgery
Definition
destruction of tissue by freezing with application of an extremely cold chemical (ex. liquid nitrogen)
Term
dermabrasion
Definition
surgical removal of epidermis frozen by aerosol spray using wire brushes and emery papers to remove scars, tattoos, and/or wrinkles
Term
debridement
Definition
removal of dead tissue from a wound or burn site to promote healing and to prevent infection
Term
curettage
Definition
cleaning; scraping a wound using a spoon-like cutting instrument called a curette; used for debridement
Term
electrosurgical procedures
Definition
use of electric current to destroy tissue; the type and strength of the current and method of application vary
Term
electrocautery
Definition
use of an instrument heated by electric current (cautery) to coagulate bleeding areas by burning the tissue (ex. to sear a blood vessel)
Term
electrodesiccation
Definition
use of high-frequency electric currents to destroy tissue by drying it; the active electrode makes direct contact with the skin lesion
Term
fulguration
Definition
to lighten; use of long, high-frequency, electric sparks to destroy tissue; the active electrode does not touch the skin
Term
incision and drainage
Definition
I&D
Term
incision and drainage (I&D)
Definition
incision and drainage of an infected skin lesion (ex. an abscess)
Term
laser
Definition
an acronym for light amplification by stimulated emission of radiation; an instrument that concentrates high frequencies of light into a small, extremely intense beam that is precise in depth and diameter; applied to body tissues to destroy lesions or for dissection (cutting of parts for study)
Term
laser surgery
Definition
surgery using a laser in various dermatologic procedures to remove lesions, scars, tattoos, etc.
Term
Mohs surgery
Definition
a technique used to excise tumors of the skin by removing fresh tissue, layer by layer, until a tumor-free plane is reached
Term
skin grafting
Definition
transfer of skin from one body site to another to replace skin that has been lost through a burn or injury
Term
autograft
Definition
graft transfer to a new position in the body of the same person
Term
heterograft or xenograft
Definition
graft transfer between different species, such as from animal to human
Term
homograft or allograft
Definition
donor transfer between persons of the same species, such as human to human
Term
chemotherapy
Definition
treatment of malignancies, infections, and other diseases with chemical agents that destroy selected cells or impair their ability to reproduce
Term
radiation therapy
Definition
treatment of neoplastic disease using ionizing radiation to deter the proliferation of malignant cells
Term
sclerotherapy
Definition
use of sclerosing agents in treating diseases (ex. injection of a saline solution into a dilated blood vessel tumor in the skin, resulting in hardening of the tissue within and eventual sloughing away of the lesion)
Term
ultraviolet therapy
Definition
use of ultraviolet light to promote healing of a skin lesion (ex. an ulcer)
Term
anesthetic
Definition
a drug that temporarily blocks transmission of nerve conduction to produce a loss of sensations (ex. pain)
Term
antibiotic
Definition
a drug that kills or inhibits the growth of microorganisms
Term
antifungal
Definition
a drug that kills or prevents the growth of fungi
Term
antihistamine
Definition
a drug that blocks the effects of histamine in the body
Term
histamine
Definition
a regulating body substance released in excess during allergic reactions, causing swelling and inflammation of tissues (ex. in urticaria--hives, hay fever, etc.)
Term
antiinflammatory
Definition
a drug that reduces inflammation
Term
antipruritic
Definition
a drug that relieves itching
Term
antiseptic
Definition
an agent that inhibits the growth of infectious microorganisms
Term
AIDS
Definition
acquired immunodeficiency syndrome
Term
BCC
Definition
basal cell carcinoma
Term
HIV
Definition
human immunodeficiency virus
Term
SCC
Definition
squamous cell carcinoma
Term
SLE
Definition
systemic lupus erythematosus
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