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Integumentary system
skin, hair nails, cutaneous glands
69
Biology
Undergraduate 1
10/14/2009

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Term
keratinocytes
Definition
cells that produce a tough fibrous tissue;
Term
what kind of cells make up the majority of the cells in the epidermis?
Definition
keratinocytes
Term
melanocytes
Definition
only in the deep stratum basale; all people have roughly same amount of them;
Term
what must melanin go through to shade nuclei from UV radiation?
Definition
they must be phagocytized by keratinocytes
Term
black/brown protective pigment
Definition
Eumelanin
Term
reddish/yello protective pigment
Definition
pheomelanin
Term
tactile (merkel) cells
Definition
very few in stratum basale; sense touch;associated with dermel nerve fiber; attached to a nerve ending in the dermis (nerve fiber)
Term
layers of the epidermis
Definition
basale,spinosum,granulosum,lucidum,corneum
Term
stratum spinosum
Definition
2nd deepest layer of the epidermis; thickest layer; conatins more living keratinocytes; produce more keratin filaments which cause the cells to flatten; conatins the dendric cells which alert the immune system
Term
Cells of the Spinosum
Definition
keratinocytes(contains most of them); Dendritic (Langerhans) cells that alert the immune system to foreign invaders
Term
Stratum Granulosum
Definition
3-5 layers of granule and vesicle containing keratinocytes
Term
lucidum
Definition
thin layer, transluscent zone; has no nuclei or organelles; filled with eledin;
Term
eledin
Definition
intermediate product of keratin production
Term
stratum corneum
Definition
contains up to 30layers; highly protective, resistant to abrasion, penetration, and water loss
Term
thickness of dermis
Definition
.2mm to .4mm
Term
dermis
Definition
composed of mostly fibrous connective tissue, mostly collogen and some elastic reticular tissue; contains blood vessels
Term
is the dermis vascular or avascular?
Definition
vascular
Term
what other structures does the dermis contain?
Definition
sweat glands, sebaceous glands, hair follicles, nail roots and nerve endings
Term
Dermal Pappillae
Definition
upward extensions of the dermis into the epidermis forming the ridges of the fingerprints
Term
dermal layers
Definition
papillary and retucular
Term
papillary layer
Definition
contains areoler tissue, allows mobility of white blood cells
Term
reticular layer
Definition
contains dense irregular tissue; deepest 4/5; has thick collagen that is responsible for stretch marks; contains adipocytes (fat)
Term
Hypodermis
Definition
subcutaneous tissue or superficial fascia; binds skin to underlying tissue; has most adipose; functions as an energy reservoir and thermal insulation; 8% thicker in women
Term
Where is male adipose tisue?
Definition
abdomenon, thighs love handles, ass
Term
Adipose in women?
Definition
thighs, boobs, above neck, back of arms, ass
Term
hemoglobin
Definition
red pigment in red blood cells; is red because of oxygen binding with it
Term
Carotene
Definition
yellow pigment from diet; color of fat; is in corneum and subaceous fat
Term
Is melanin hereditary?
Definition
yes
Term
cyanosis
Definition
blueness of skin due to deficiency of oxygen circulating in blood
Term
Erythma
Definition
redness due to dialated cutaneous vessels; result of anger, sunburn, embarrasment
Term
Jaundice
Definition
yellowing of skin & sclera; due to liver disease, which causes excess bilirubin in blood
Term
Addison Disease
Definition
deficiency o glucocorticoid hormone; causes bronzing,; causes rapid water loss
Term
Pallor
Definition
pale color from lack of blood flow
Term
albinism
Definition
genetic lack of melanin
Term
hemotoma
Definition
bruise; visibly clotted blood under the skin
Term
hemangiomas
Definition
birthmarks; benign tumers of dermal blood capillaries
Term
freckles
Definition
flat aggregations of melanocytes; they are hereditary, or can form from sun exposure
Term
moles
Definition
elevated melanized skin
Term
nails
Definition
grow 1mm per week;allows for sensitive fingertips; derived from stratum corneum
Term
hyproxemia
Definition
diagnosed from clubbing of finger nails
Term
iron deficiency can be diagnosed how?
Definition
spoon-like shape of the nail
Term
lunute
Definition
white crest on nail that covers a thick stratum basale
Term
purposes of skin
Definition
resistance to infections/trauma; other barrier functions;vitamin d synthesis;sensation; thermoregulation; nonverbal communication
Term
pilus
Definition
filament of kertinzed cells; composed of hard keratin, but less than nails (to make more flexible); toughened by disulfide bridges between molecules; hair
Term
Shaft of hair
Definition
visible above skin; in cross section (like tree trunk)
Term
root of hair
Definition
below within follicle
Term
follicle of hair
Definition
oblique tube within the skin
Term
bulb of hair follicle
Definition
swelling in base where hair originates
Term
papilla in bulb of hair
Definition
provides nutrients
Term
Growth of hair
Definition
1mm every 3days for 2-4yrs, before going into dorment phase lasting 3-4 months
Term
Hirsutism
Definition
abnormal hairiness in children or women caused by ovarian tumors or adrenal cortex produces too much testosterone
Term
Alopecia
Definition
baldness; expressed with male levels of testosterone; passed on the x chromosome; occurs with women ONLY in homozygous recessive
Term
functions of hair
Definition
-alerts us of parasites; sensory
-scalp for heat retention and sunburn protection
-recognition
sexual maturityprevent foreighn objects form getting in nostrils ear canals or eyes
-eybrows express emotion
Term
cutaneous glands
Definition
sweat or sudiferous glands
Term
merocrine
Definition
most numerous gland; watery perspiration; located everywhere especially in palms and soles and forehead
Term
apocrine
Definition
located in groin, anal, axillary, beard, ducts of hair follicles; is more milky/fatty acid/thick
Term
Subaceous gland
Definition
produces sebum; prevents drying of skin/hair
Term
ceruminous glands
Definition
only in ear canal; produces cerumen/earwax
Term
mammary
Definition
milk
Term
dermatitis
Definition
inflammation due to infection, fungi, bacteria
Term
tinea
Definition
fungal infection (ringworm)
Term
rosocea
Definition
red rash of nose & cheeks;
Term
sebhorrhiec
Definition
reoccurring patches of scaly white and/or yellow skin
Term
warts
Definition
viral infection; hpv
Term
Acne
Definition
inflammation of subaceous gland; affects 80% of ppl;microorganism feed on glycerol
Term
comedos
Definition
white head; blackhead if oxidized by being "open"
Term
Accutane
Definition
inhibits sebum production
Term
eczema
Definition
genetic skin disorder; not contagious; dry itchy skin; no cure
Term
Accutane
Definition
inhibits sebum production
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