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cells covering external and internal surfaces of the body |
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thin outer layer of the skin |
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flat, scalelike epithelial cells comprising the outermost epidermis |
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deepest layer of epidermis |
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cell in the basal layer that gives color to the skin |
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dark brown to black pigment contained in melanocytes |
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dense, fibrous connective tissue layer of the skin |
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oily substance secreted by the sebaceous glands |
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sweat glands (sudor = sweat; ferre = to bear) |
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connective and adipose tissue layer just under the dermis |
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protein substance in skin and connective tissue (koila = glue; gen = producing) |
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outgrowth of the skin composed of keratin |
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outgrowth of the skin at the end of each finger and toe, composed of keratin |
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hard protein material found in the epidermis, hair, and nails |
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an area of pathologically altered tissue (two types: primary and secondary) |
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lesions arising from previously normal skin |
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a flat, discolored spot on the skin up to 1cm across (e.g. a freckle) |
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a flat, discolored area on the skin larger than 1cm (e.g. vitiligo) |
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a solid mass on the skin up to 0.5cm in diameter (e.g. a nevus or mole) |
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a solid mass greater than 1cm in diameter but limited to the surface of the skin |
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a solid mass greater than 1cm, extending deeper into the epidermis |
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solid mass larger than 1-2cm |
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an area of localized skin edema (swelling) (e.g., a hive) |
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little bladder; an elevated, fluid-filled sac (blister) within or under the epidermis up to 0.5cm in diameter (e.g. a fever blister) |
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a blister larger than 0.5cm (e.g. a second-degree burn; bulla = bubble) |
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a pus-filled sac (e.g. a pimple) |
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lesions that result in changes in primary lesions |
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gnawed away; loss of superficial epidermis leaving an area of moisture but no bleeding (e.g. area of moisture after rupture of a vesicle) |
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an open sore on the skin or mucous membrane that can bleed and scar; sometimes accompanied by infection (e.g. decubitus ulcer) |
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a linear crack in the skin |
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a think flake of exfoliated epidermis (e.g. dandruff) |
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dried residue of serum (body liquid), pus, or blood on the skin (e.g. in impetigo) |
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mark left by the healing of a sore or wound, showing the replacement of destroyed tissue by fibrous tissue (cicatrix = scar) |
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an abnormal overgrowth of scar tissue that is thick and irregular (kele = tumor) |
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lesions of a blood vessel |
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a small, round, bright red blood vessel tumor on the skin, often on the trunk of the elderly |
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purpura; lesions resulting from hemorrhages into the skin |
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Telangiectasia or spider angioma |
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a tiny, red blood vessel lesion formed by the dilation of a group of blood vessels radiating from a central arteriole, most commonly on the face, neck, or chest (telos = end) |
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spot; reddish-brown, minute hemorrhagic spot(s) on the skin that indicate a bleeding tendency; a small purpura |
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bruise; a black and blue mark; a large purpura (chymo = juice) |
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skin tumors arising from the epidermis |
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birthmark; a congenital malformation on the skin that can be epidermal or vascular, also called a mole |
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a mole with precancerous changes |
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an epidermal tumor caused by a papilloma virus; also called a wart |
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fox mange; baldness; natural or unnatural deficiency of hair |
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appearance of a skin lesion |
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a general term for skin eruption, most often associated with communicable disease |
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skin color due to the presence of melanin |
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loss of melanin pigment in the skin |
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areas of skin lacking color due to deficient amounts of melanin |
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darkened areas of skin caused by excessive amounts of melanin |
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production of purulent matter (pus) |
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hives; an eruption of wheals on the skin accompanied by itch (urtica = stinging nettle) |
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inflammation of the sebaceous glands and hair follicles of the skin evidenced by comedones (blackheads), pustules, or nodules on the skin (acne = point) |
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a hereditary condition characterized by a partial or total lack of melanin pigment (particularly in the eyes, skin, and hair) |
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injury to body tissue caused by heat, chemicals, electricity, radiation or gases |
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a burn involving only the epidermis, characterized by erythema and hyperesthesia (excessive sensation) |
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a burn involving only the epidermis and the dermis, characterized by erythema, hyperesthesia, and vesications (blisters) |
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a burn involving all layers of the skin, characterized by the destruction of the epidermis and dermis with damage or destruction of subcutaneous tissue |
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inflammation of the skin characterized by erythema, pruritus (itching) and various lesions |
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comedo (pl. comedos, comedones) |
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a blackhead caused by a plug of sebum (oil) within the opening of a hair follicle |
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to boil out; term often used interchangeable with dermatitis to denote a skin condition characterized by the appearance of inflamed, swollen papules and vesicles that crust and scale, often with sensations of itching and burning |
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boil; a painful nodule formed in the skin by inflammation originating in a hair follicle, caused by staphylococcosis |
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skin infection consisting of clusters of furuncles (carbo=small glowing embers) |
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localized collection of pus in a cavity formed by the inflammation of surrounding tissues, which heals when drained or excised (abscessus = a going away) |
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an eating sore; death of tissue associated with a loss of blood supply |
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exanthematous viral disease |
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eruption of the skin caused by a viral disease (exanthema = eruption) |
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herpes simplex virus type I (HSV-1) |
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transient viral vesicles (e.g. cold sores or fever blisters) that infect the facial area, especially the mouth and nose (herpes = creeping skin disease) |
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herpes simplex virus type II (HSV-2) |
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sexually transmitted, ulcerlike lesions of the genital and anorectal skin and mucosa; after initial infection the virus lies dormant in the nerve cell root and may recur at times of stress |
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a viral disease affecting the peripheral nerves, characterized by painful blisters that spread over the skin following affected nerves, usually unilateral; also known as shingles (zoster = girdle) |
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highly contagious, bacterial skin inflammation marked by pustules that rupture and become crusted, most often around the mouth and nostrils |
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thickened areas of epidermis |
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benign, wartlike tumors (more common on elderly skin) |
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actinic keratoses or solar keratoses |
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localized thickening of the skin caused by excessive exposure to sunlight, a known precursor to cancer (actinic = ray; solar = sun) |
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a chronic autoimmune disease characterized by inflammation of various parts of the body (lupus = wolf) |
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limited to the skin; evidenced by a characteristic rash, especially on the face, neck and scalp |
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systemic lupus erythematosus |
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a more severe form of lupus involving the skin, joints, and often vital organs (e.g. lungs or kidneys) |
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malignant cutaneous neoplasm |
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malignant tumor of squamous epithelium |
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malignant tumor of the basal layer of the epidermis (most common type of skin cancer) |
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a malignant tumor composed of melanocytes |
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a malignant tumor of the walls of blood vessels appearing as painless, dark bluish-purple plaques on the skin; often spreads to lymph nodes and internal organs |
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inflammation of the fingernail or toenail |
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inflammation of the nail fold |
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infestation with lice that causes itching and dermatitis (pediculo=louse) |
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head lice (capitis = head) |
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lice that generally infect the pubic region; sometimes also hair of the axilla, eyebrows, lashes, beard, or other hairy body surfaces; also called crabs (pubis = groin) |
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itching; a chronic, recurrent skin disease marked by silver-gray scales covering red patches on the skin; results from overproduction and thickening of skin cells, commonly at elbows, knees, genitals, arms, legs, scalp, and nails |
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contagious disease caused by a parasite (mite) that invades the skin, causing an intense itch, most often at articulations between the fingers, toes, or elbow (scabo = to scratch) |
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skin conditions marked by the hypersecretion of sebum from the sebaceous glands |
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group of fungal skin diseases identified by the body part affected, including tinea corporis (body), commonly called ringworm; and tinea pedis (foot) also called athlete’s foot |
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the condition caused by the destruction of melanin that results in the appearance of white patches on the skin |
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removal of a small piece of tissue for microscopic pathologic examination |
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removal of an entire lesion |
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removal of a selected portion of a lesion |
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technique using a surgical blade to “shave” tissue from epidermis and upper dermis |
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culture and sensitivity (C&S) |
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Technique of isolating and growing colonies of microorganisms to identify a pathogen and to determine which drugs might be effective for combating it |
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surgical technique involving cutting a thin piece of tissue from a frozen specimen for immediate pathologic examination |
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methods for determining the reaction of the body to a given substance by applying it to, or injecting it into, the skin; commonly used in treating allergies |
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test in which a substance is applied to the skin through a scratch |
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test in which a substance is applied topically to the skin on a small piece of blotting paper or wet cloth |
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destruction of tissue by freezing with application of an extremely cold chemical (e.g. liquid nitrogen) |
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surgical removal of epidermis frozen by aerosol spray using wire brushes and emery papers to remove scars, tattoos, or wrinkles |
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removal of dead tissue from a wound or burn site to promote healing and to prevent infection |
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cleaning; scraping a wound or burn site to promote healing and to prevent infection |
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electrosurgical procedures |
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use of electric currents to destroy tissue; strength of the current and method of application vary |
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use of an instrument heated by electric current (cautery) to coagulate bleeding areas by burning the tissue (e.g. to sear a blood vessel) |
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use of high-frequency electric currents to destroy tissue by drying it; the active electrode makes direct contact with the skin lesion (dessicate = to dry up) |
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to lighten; use of long, high-frequency, electric sparks to destroy tissue; the active electrode does not touch the skin |
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Chemosurgery or chemical peel |
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technique for restoring wrinkled, scarred, or blemished skin by applying an acid solution to “peel” away the top layers of the skin |
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incision and drainage (I&D) |
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incision and drainage of an infected skin lesion (e.g. an abscess) |
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surgery using a laser in various dermatological procedures to remove lesions, scars, tattoos, etc. |
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acronym for light amplification by stimulated emission of radiation; the instrument produces a small, extremely intense beam that is precise in depth and diameter; it is applied to body tissues to destroy lesions or to dissect (cutting parts for study) |
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technique used to excise tumors of the skin by removing fresh tissue layer by layer until a tumor-free plane is reached |
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transfer of skin from one body site to another to replace skin lost through a burn or injury |
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graft transfer to a new position in the body of the same person (auto=self) |
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graft transfer from one animal species to one of another species (hetero=different) |
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donor transfer between persons of the same species, such as human to human (homo=same) |
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treatment of malignancies, infections, and other diseases with chemical agents that destroy selected cells or impair their ability to reproduce |
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treatment of neoplastic disease using ionizing radiation to deter proliferation of malignant cells |
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use of sclerosing agents in treating diseases (e.g. injection of a saline solution into a dilated blood vessel tumor in the skin, resulting in hardening of the tissue within and eventual sloughing away of the lesion) |
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use of ultraviolet light to promote healing of a skin lesion (e.g. an ulcer) |
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a drug that temporarily blocks transmission of nerve conduction to produce a loss of sensations (e.g. pain) |
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a drug that kills or inhibits the growth of microorganisms |
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a drug that kills or prevents the growth of fungi |
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a drug that blocks the effects of histamine in the body |
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a regulating body substance released in excess during allergic reactions causing swelling and inflammation of tissues [e.g. in urticaria (hives) or hay fever] |
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a drug that reduces inflammation |
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a drug that relieves itching |
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an agent that inhibits the growth of infectious microorganisms |
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