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INTEGUMENT
Test 1
28
Biology
Graduate
06/29/2010

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Term
Skin is the largest organ in body
Definition
15-20% of body mass
Term
Functions of the Skin
Definition
-Protection
-Thermoregulation
-Excretion
-Sensory reception
-Synthesis of Vitamen D
Term
Skin layers
Definition
Epidermis
Dermis
Hypodermis
Term
Epidermis
Definition
Top Layer: Statified squamous keratinized epithelium
Term
Keratinocytes
Definition
principal cells of Epidermis: deepest layer or epidermis. Lifespan=15-30days
Term
Keratin
Definition
produced by Keratinocytes: Protein which protects skin. amt. increases as it moves upward
Term
Acascular
Definition
Dosnt contain blood vessels: Epidermis
Term
Melanocytes
Definition
Cell type in Epidermis, Derived from NEURAL CREST: synthesize pigment melanin that absorbs UV, thus protecting the dividing cells of skin from damage
Term
Melanin
Definition
produced by Melanocytes from TYROSINE with participation of enzyme TYROSINASE
Term
Carotene
Definition
yellow coloring of skin and in the adipose cells
Term
Langerhans cells
Definition
Cell type of Epidermis: Derived from BONE MARROW; immune responses as antigen-presenting cells
Term
Merkel's cells
Definition
Type of cell in Epidermis: Fuction as Mechanoreceptors
Term
Dermis
Definition
Composed DENSE CT rich in COLLAGEN TYPE 1 and ELASTIC FIBERS
Term
Fibroblasts
Definition
Principal cell type in Dermis
Term
Dermal Layer
Definition
naked and free encapsulated nerve endings
provide mechanical strength and elasticity of skin
primary source of nutrition to the epidermis through blood vessels
Term
Papillary Layer
Definition
Dermal layer: LOOSE CT forms contour of DERMAL RIDGES that interdigitate w/ corresponding EPIDERMAL RIDGES of the deepest layer of Epidermis
Term
Reticular layer
Definition
DENSE CT: countinuous with HYPODERMIS
Term
Difference in thickening of dermis
Definition
Back- thick
Abdomen- thin
Term
Hypodermis
Definition
LOOSE CT:(usually adipose)
"superficial Fascia"
Loosely binds the skin to the subjacent organs
NOT CONSIDERED PART OF THE SKIN
Term
Sebaceous Glands
Definition
SEBUM-oily substance acts as lubricant for skin, protects from drying.
HOLOCRINE GLANDS
associated with hair follicles
Term
Sweat Glands
Definition
found in most places on body more abundant on palms and soles
Term
Hair
Definition
SHAFT:ROOT strongly influenced by sex hormones, adrenal and thyroid glands
Term
Skin Repair Phases
Definition
Hemostasis
Inflammation
Proliferation
Remodeling
Term
Hemostasis
Definition
Vasoconstriction
Clot formation
Term
Inflammation
Definition
influx of neutrophilis and macrophages that remove dead tissue and bacterial by phagocytosis
Term
Proliferation
Definition
Proliferation of fibroblasts in wound bed
Proliferation and new tissue deposition
New blood vessels are formed (angiogenesis)
proliferation of keratinocytes in deep layer of epidermis
Term
Remodeling
Definition
New collagen matrix becomes cross-linked and organized
Term
Age-Related changes in skin
Definition
thining
num. of melanocytes decreases
num. sweat glands and sebacous glands decrease
- lack of sweating (cant control body temp), skin dries up
looses elasticity
adipose tissue in hypodermis thins
INCREASE BRUISING AND SKIN TEARS
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