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integ
final
78
Medical
Graduate
09/20/2012

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Cards

Term
squamous cell carcinoma
Definition
full thickness atypia, sunlight exposure
Term
kaposi's sarcoma
Definition
spindle shaped cells, slit lke spaces filled with red cells, focal hemorrhages/hemosiderin deposits, HIV+
Term
tetanus prophylaxis
Definition
toxoid immunization + debridement
Term
actinic keratosis
Definition
cellular atypia in lower epidermis, basophilic degeneration of collagen, malignant transformation to Squamous cell carcinoma
Term
leser-trelat
Definition
multiple seborrheic keratoses, internal malignancy
Term
escharotomy
Definition
restore circulation in burn pt
Term
chlorhexidine
Definition
surgical antiseptic
Term
xanthoma/xanthelasma
Definition
foamy histiocytes, touton giant cells
Term
basal cell carcinoma
Definition
proliferating basal cells protruding from the epidermis, forming large nests extendind in into the dermis, radial arrangemnet of cells at periphery, mucinous CT stroma
Term
progressive sclerosis
Definition
CREST (calcinosis, raynoud's, esophageal dysfxn, sclerodactyl, telangiectasia)
Term
basal cell carcinoma
Definition
most common carcinoma of the skin, rodent ulcer, pearly rolled border
Term
nevus of spitz
Definition
spindle shaped/plumpcells with nuclear irregularities, children
Term
mycosis fungoides
Definition
scaly plaques, malignant T cells, pautrier abscess, cerebriform nuclei
Term
keratoacanthoma
Definition
central keratin plug
Term
hydroquinone (transient)
monobenzene (kills melanocyte)
Definition
inhibits tyrosinase
Term
dermatomyositis
Definition
heliotrope rash, gottren's sign, "shawl sign"
Term
lentigo
Definition
benign hyperpigmented malanocyte hyperplasia
Term
poikiloderma of civatte
Definition
telangiectasis in elderly pt, UVA exposure
Term
nodular melanoma
Definition
melanoma in vertical growth phase, poor prognosis
Term
photochemotherapy (PUVA)
Definition
oral psoralen (trioxsalen, methoxsalen)
Term
hypermetabolic state
Definition
fatal inanition in burn pts
Term
retinoic acid
Definition
binds RAR (member of thyroid/steroid superfamily), contraI in pregnant women
Term
etretinate
Definition
retinoid approved for psoriasis
Term
glucocorticoids
Definition
inhibits keratinocyte mitosis, immunosuppressive, antinflammatory
Term
granulation tissue
Definition
"proud flesh" inflammatory cells + proliferating capillaries in wound
Term
wound contamination
Definition
most sensitive indicator of sterile technique in operating rooms
Term
5-FU
Definition
topical cream for actinic keratosis
Term
tumor thickness (vertical, breslow scale)
Definition
strongest prognostic variable in melanoma
Term
discoid lupus
Definition
immunoflourescence: granular band of IgG + complement along the DE junction
Term
full thickness/3rd +4th degree burns
Definition
thermal injury that is insensate due to nerve damage
Term
milia
Definition
complication of chemical peels
Term
cutis rhomboidalis nuchae
Definition
thickened skin on a farmer/sailor
Term
partial thickness/ second degree burn
Definition
painful thermal injury with blistering
Term
Basal cell carcinoma
Definition
ulcer on the nose with nested cells
Term
colonize burn wounds
Definition
s. aureus, streptococcus, pseudomonas, candida, MRE/VRE
Term
dysplastic nevi
Definition
AD inheritance, runs in families
Term
malignant fibrous hitiocytoma
Definition
storiform pattern of pleomorphic cells
Term
stop the burning process, cool the area
Definition
initial tx of a burn
Term
isoretinoin
Definition
increase keratinocyte turnover, decrease size of sebaceous glands, teratogen
Term
psorlans (trioxsalen, methoxsalen)
Definition
form DNA adducts
Term
tertiary wound healing
Definition
closure of granulating wound before it is healed
Term
increase wound infection
Definition
old age, shock, DM, nutritional deficits, alcoholism, steroids, chemo
Term
contaminated wound surgery
Definition
peritonitis with fever, leukocytosis, fever, toxic septic state
Term
corticosteroids
Definition
decrease AA cascade, decrease cytokines, decrease inflammatory cells, tachyphylaxis
Term
lentigo maligna melanoma
Definition
pigmented papule on brown patch, :hutchinson's freckle"
Term
timing of antibiotics in surgery
Definition
choose short half-life, give as close to incision + 4-6 hrs later
Term
clobetasol propionate
Definition
most potent topical corticosteroid
Term
most common nosocomial infections causeing fever
Definition
pulmonary infection or empyema, UTI, organ failure, wound infection
Term
cylindroma
Definition
apocrine origin, "turban tumor"
Term
chronic cutaneous lupus
Definition
topical corticosteroids + antimalarials (chloroquine) + azathioprine
Term
acrochordon (aka skin tag, fibroepithelial polyp)
Definition
pedunculated papule on diabetic pt
Term
depth of injury
Definition
burn classification
Term
imiquimod
Definition
shrink/cure basal cell carcinoma, 3 months therapy
Term
superficial spreading (70%)
Definition
most common type of melanoma
Term
finasteride
Definition
5alpha-reductase inhibitor, decrease libido, gynecomastia, trichogenic
Term
favre rocouchet
Definition
nodular elastoidosis, yellow skin, giant open comedones
Term
squamous cell carcinoma
Definition
second most common cutaneous malignancy
Term
minoxidil
Definition
increase cutaneous blood flow to scalp
Term
trioxsalen
Definition
repigmentation in vitiligo
Term
morphea
Definition
localized sclerosis with tethered skin
Term
seborrheic keratosis
Definition
"pasted on" papule, horn cysts
Term
marjolin's ulcer
Definition
transformation of a non-healing ulcer, burn wound, osteomyelitits to squamous cell carcinoma
Term
hypopigmentation + depth of melanocytes
Definition
vitiligo
Term
warts
Definition
duct tape
Term
osteoporosis, immunosupression
Definition
complication of systemic glucocorticoids
Term
increased potency
Definition
flourinated topical glucocorticoids
Term
used in psoriasis
Definition
PUVA phototherapy
Term
lateral venous system varicosities
Definition
indications for sclerotherapy
Term
basal cell carcinoma + squamous cell carcinoma with poorly circumscribed borders
Definition
indications for Moh's microsurgery
Term
+ ANA in subacute cutaneous lupus dx
Definition
typically non-scarring and exhibits an elevation of ANA in 50-72% of pts
Term
most common population that acquires CLE
Definition
hatians that experience trauma and UV exposure
Term
management of acne - increasing epidermal cell TO
inhibits sebaceous gland size
CI in pregnancy
Definition
isoretinoin
Term
rodent ulcer
Definition
BCC
Term
mitosis is common, cells at periphery arranged radially, degeneration of collagen in upper dermis
Definition
actinic keratosis
Term
spindle or plump cells with nucleau irregularities but is not malignant
Definition
nevus of spitz
Term
fever
peritonitis
leukocytosis
toxic septic state
Definition
most important indicators for re-operation of a contaminated wound
Term
pearly papule or nodule with rolled/raised pearly borders and telangiectasia
Definition
BCC
Term
common in the elderly
brown raised macule
not induced by the sun
Definition
seborrheic keratosis
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