Shared Flashcard Set

Details

Inflammation Matching - Exam #5
Inflammation actions and drugs
21
Pharmacology
Undergraduate 2
04/26/2015

Additional Pharmacology Flashcards

 


 

Cards

Term
Histamine
Definition
pruritus (itching)
Term
Bradykinin
Definition
activates pain receptor
Term
Thromboxane
Definition
promotes platelet aggregation
Term
Leukotriene B4
Definition
chemotactic for neutrophils
Term
Nuclear Factor
Definition
agent that activates DNA transcription
Term
PGE2 (Prostaglandin E2)
Definition
induces fever and hyperalgesia
Term
TXA2 (Thromboxane A2)
Definition
induces vasoconstriction and platelet aggregation
Term
PGI2 (Prostacyclin)
Definition
induces vasodilatation and inhibits platelet aggregation
Term
IL-1, TNF
Definition
chemokines that induce chemotaxis and endothelial cell activation
Term
C3a, C3b
Definition
complement fragments useful as opsonins
Term
hyperemia
Definition
increase blood flow to an area
Term
exudate
Definition
leakage of protein-rich fluid from the circulation
Term
chemotactic factors
Definition
WBCs that predominate in an area of acute inflammation
Term
opsonins
Definition
Chemicals that attract WBCs
Term
neutrophils
Definition
substances that bind to antigens and facilitate phagocytosis
Term
Arachidonic acid
Definition
released from cell membrane by phospholipase a2
Term
cyclooxygenase
Definition
enzyme needed for synthesis of prostaglandins
Term
lipoxygenase
Definition
enzyme needed for synthesis of leukotrienes
Term
cytokines
Definition
substances released by activated wbcs to activate other immune cells
Term
thromboxane
Definition
synthesized primarily by activated platelets
Term
clotting cascade
Definition
sequence of activated proteases that eventually cause an insoluble fibrin meshwork
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