Term
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Definition
include changes in the plasma proteins, sketela muscle catabolism, and increased leukocytes. |
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Term
what do cytokines affect? |
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Definition
the thermoregulatory center in the hypothalamus to produce fever. |
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Term
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Definition
severe bacterial infection |
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Term
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Definition
regeneration of tissue cells |
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Term
what happens during connective tissue replacement and regeneration? |
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Definition
cell migration, proliferation, and differentiation. (also, interaction with extracellular matrix) |
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Term
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Definition
contain the functioning cells of an organ. (renal tubules, heptocytes) |
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Term
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Definition
consist of the supporting connective tissues, blood vessels, extracellular matrix, blood vessels, and nerve fibers |
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Term
body cell types are divided into 3 types, what are they? |
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Definition
labile, stable, or permanent. |
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Term
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Definition
continue to divide and replicate through life. ex. skin |
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Term
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Definition
normally stop developing when puberty ceases. they will regerate when confronted with a proper stimulus |
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Term
what are examples of stable cells? |
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Definition
liver cells, kidney, smooth muscle... |
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Term
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Definition
cannot undergo regeneration and mitotic division. nerve cells, cardiac, skeletal muscles. They will get replaced with scar tissue. |
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Term
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Definition
glitening red, moist connective tissue. |
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Term
what is involved with the formation of granulation tissue? |
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Definition
new capillaries (angionesis), fibrogenesis, and the involution of scar tissue. |
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Term
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Definition
involves the generation and sprouting of new blood vessels from pre-existing vessels |
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Term
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Definition
the influx of activated fibroblasts that secrete ECM. (fibronectin, hyaluronic acid, proteoglycans and collagen.) |
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Term
what makes a scar waterproof? |
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Definition
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Term
how does scar formation occur? |
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Definition
emigration and proliferation of fibroblasts, deposisting of ECM. collagen deposits. vascular degeration makes the scar appear pale. |
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Term
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Definition
surgical insision that is closed. |
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Term
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Definition
slower healing. it heals with an open wound. larger amount of scar tissue. |
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Term
vascular phases of healing |
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Definition
brief constriction, vasodilation, increased permiability, plasma leakage. |
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Term
cellular phase of inflammation |
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Definition
migration of phagocytotic WBC's tht digest foreign and broken material. |
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Term
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Definition
phagocytosis. release of growth factors that stimulate epitheleal growth, angiogenesis, and attract fibroblasts. |
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Term
T or F: a wound can heal without neutrophils but it can't heal without macrophages |
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Definition
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Term
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Definition
tissue building, fibroblast is the key cell-it makes collagen and it secretes angionesis and skin cell proliferation and migration |
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Term
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Definition
the migration, proliferation, and differentiation of skin cells to form a new layer. |
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Term
what are the 3 pahses of wound healing? |
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Definition
inflammatory phase, proliferation phase, remodeling phase. |
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Term
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Definition
the wound will continue to have fibroblasts and collagen deposits to increase tensile strength. |
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Term
how does secondary intention heal during the remodeling phase? |
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Definition
it will undergo wound contraction which will shrink the scar size. |
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Term
how does hypoxia affect the cell? |
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Definition
hypoxia causes cell swelling |
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Term
what is an example of systemic? |
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Definition
swollen ankles from edema causes by cardiac problems |
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Term
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Definition
swollen ankles from a broken ankle |
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Term
what is a very good example of cellular hypertrophy? |
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Definition
heart cells will expand due to hypertension to have more strength to pump blood. cardiac cells cant divide so it has to swell to get stronger. |
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Term
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Definition
increased numbers of circulating leukocytes |
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Term
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Definition
it shows where the inflammation is |
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Term
is c reactive proteins are elevated it means that....? |
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Definition
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Term
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Definition
layers of the skin have separated |
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Term
what are the stages in the proliferative phase? |
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Definition
granulation tissue, epitheliazation, collagen tissue formation, fibrous scar formation |
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