Term
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Definition
ADRs of Lamivudine and Emtricitabine (NRTIs) |
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Term
hypersensitivity reaction have to test patient for HLA-B 5701 to see if they are at an increased risk of the hypersensitivity reaction |
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Definition
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Term
Myelosuppression - seen as neutropenia from CBC |
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Definition
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Term
pancreatitis peripheral neuropathy |
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Definition
ADR of Didanosine and Stavudine (NRTIs) |
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Term
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Definition
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Term
hepatic metabolism
hepatic dosing adjustment unknown
CYP3A4 DRUG INTERACTIONS
no renal dosing
class side effect: rash |
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Definition
common ADRs of NNRTIs (nevirapine, delavirdine, efavirenz, etravirine) |
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Term
pregnancy category D neuropsychiatric effects |
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Definition
ADRs of Efavirenz (NNRTI) |
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Term
women CD4 count < 250 men CD4 count < 400 |
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Definition
ADRs of Nevirapine (NNRTI) |
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Term
hepatic metabolism no renal dosing, except atazanavir in HD notorious for CYP3A4 DRUG INTERACTIONS GI ADRs common, most require administration with food (except indinavir which is administered on an empty stomach) rash: common with darunavir and tipranavir (sulfonamide moieties), amprenavir, fosamprenavir hyperglycemia fat maldistribution possible increased bleeding episodes in patients with hemophilia diarrhea: common with fosamprenavir, lopinavir/ritonavir, nelfinavir, tipranavir increased liver enzymes: common with tiprinavir increased cholesterol and TGs: common with ritonavir |
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Definition
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Term
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Definition
ADRs of Enfuvirtide (fusion inhibitor) |
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Term
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Definition
ADR of Maraviroc (entry inhibitor) |
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