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Infections of the abdominal cavity
How to treat infections of the abdominal cavity
22
Medical
Professional
02/11/2012

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Cards

Term
What are the six organs of the peritoneal cavity?
Definition
Stomach
Large Bowel
Smal Bowel
Liver
Gallbladder
Spleen
Term
What are the 6 things found in the retroperitoneal cavity?
Definition
Duodenum
Pancreas
Kidneys
Adrenal Glands
Aorta and vena cava
Most mesenteric vascular structures
Term
What is an abscess?
Definition
Purulent collection of fluid separated from the surrounding tissue by a wall of inflammatory cells and adjacent organs.
Term
What are the three main causes of Primary Peritonitis?
Definition
Spontaneous bacterial peritonitis is an infection without an evident cause. It's generally caused by:
Peritoneal dialysis
Cirrhosis with ascites
Nephrotic syndrome
Term
In general, how many organisms are involved in primary peritonitis?
Definition
One
Term
If your primary peritonitis is caused by cirrhosis, what is the most likely pathogen?
Definition
E coli
Term
If your primary peritonitis is caused by peritoneal dialysis, what is the most likely pathogen?
Definition
Staph Epidermidis or staph aureus.
Term
What's the most common cause of secondary peritonitis?
Definition
Some type of perforation of the GI tract
Term
In secondary Peritonitis, what are the most common pathogens. Give answer in terms of Gram negative, gram + and anaerobic.
Definition
Gram negative: E coli
Gram positive: Streptococcus or enterococcus
Anaerobes: bacteroides, specifically B fragilis
Term
What's the general trend for microorganisms in the GI tract?
Definition
The deeper you go, the more gram negative they are and the more likely you will find anaerobes.
Term
What are the flora of the female genital tract?
Definition
Lactobacilli
Eubacteria
Clostridia
Anaerobic strep
aerobic strep
Staph Epi
Term
What is a capsule?
Definition
It's a hard shell found in abscesses that makes them harder to treat
Term
What types of blood cultures would make you suspect secondary peritonitis?
Definition
Anytime bacteroides gets into the blood
OR
anytime you have two enteric bacteria in the blood
Term
What is tertiary peritonitis?
Definition
It's an infection that comes back 48 hours after what was thought to be adequate treatment of secondary.
Term
How do you treat primary peritonitis caused by Cirrhosis?
Definition
The most likely agent is E coli.
Treat with Cefotaxime
MAYBE
add clinda or metronidazole if you suspect anaerobes, too
Term
How do you treat primary peritonitis caused by peritoneal dialysis?
Definition
Vanc + 3rd gen ceph
OR
AG + 3rd gen ceph
Vanc is for G+, 3rd gen ceph for G-
Term
How do you treat mild to moderate community acquired secondary peritonitis? (6+6)
Definition
Ticarcillin-clavulante
Cefoxitin
Ertapenam
Moxiflaxacin
Tigecycline
Metronidazole + one of the following: Cefazolin, cefuoxime, ceftriaxone, cefotaxime, levoflaxacin, or ciprofloxcin
Term
What is the difference between how you treat mild to moderate community acquired Peritonitis vs high severity?
Definition
You cover for enterococcus faecalis in more severe cases because it's more likely to cause severe cases.
Term
how do you treat severe community acquired secondary peritonitis?(5+4)
Definition
Imipenem-cilastatin, Meropenam, or doripenam
Piperacillin-tazobactam
Metronidazole + one of the following:
Cefepime, ceftazidime, ciproflaxacin, or levofloxacin
Term
How do you treat health care acquired secondary peritonitis?
Definition
Imipenem-cilastatin, Meropenam, or doripenam
Piperacillin-tazobactam
Metronidazole + one of the following:
Cefepime, ceftazidime, ciproflaxacin, or levofloxacin

PLUS
antifungal if you suspect candida
PLUS
MRSA coverage for those colonized with MRSA or significant prior exposure to abx.
Term
How long do you treat primary peritonitis?
Definition
Cirrhosis and ascites = 5 days
Peritoneal dialysis = 14 days
Term
how long do you treat secondary peritonitis?
Definition
4-7 days unless you need to go longer
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