Shared Flashcard Set

Details

Infection and Immunity 2- Lecture 17
Viral Exanthems (rashes)
36
Medical
Professional
04/29/2013

Additional Medical Flashcards

 


 

Cards

Term

Rubeola

- what is it

- how spread

- 4 symptoms

Definition

measles virus

 

respiratory droplets


(4 "C's") cough, coryza, conjunctivitis, Koplik spots

Term

Describe the rash in Rubeola

- color

- dispersion

- blanching?

- spread

Definition

Initially discrete reddish
lesions that blanch


lesions quickly merge together and
ultimately become brownish


rash spreads cephalocaudally (from head->down)

Term
3 possible complications of Rubeola
Definition

otitis media


pneumonia due to virus (giant cell pneumonitis) or bacterial superinfection


encephalitis

Term
2 ways to prevent Rubeola infection
Definition
immune serum globulin
live attenuated virus vaccine
Term

Rubella virus

- what it causes

- spread

- 3 symptoms

Definition

German measles

 

spread via respiratory droplets


–lymphadenopathy
–polyarthralgia
- rash is milder and more rapid (“three day measles”)

Term
3 possible complications of german measles
Definition
- congenital rubella (ophthalmologic, cardiac, auditory, neurologic) aka eyes, ears, head, heart
- encephalitis
- thrombocytopenia
Term
2 ways to prevent German measles infection
Definition
–immune serum globulin
–live attenuated virus vaccine
Term

Roseola

- aka ___

- 2 microbes that cause it

- spread

- 2 main symptoms

Definition

- aka exanthem subitum

- From human herpesvirus 6 and 7

- spread via close contact

- high fever in young infant followed by erythematous maculopapular rash

Term
2 complications from a Roseola infection
Definition

- Febrile seizures

- In immunocompromised pt.: hepatitis, bone marrow suppression, encephalitis, etc.

Term

Fifth disease

- aka ___

- microbe that causes it

- how spread

Definition
- aka erythema infectiosum
- by parvovirus B19
- spread via respiratory secretions
Term
2 symptoms of Fifth disease & describe the timing of each
Definition
–flu-like illness followed 7 -10 days later by
–facial rash -“slapped cheek”
–symmetric maculopapular, lace-like rash
–spreads from extremities to trunk
Term

How Fifth disease manifests

- in utero

- in adults

- in chronic hemolytic anemia

- in immunodeficiency

Definition
–in utero infection -fetal hydrops (extreme edema) and death
–in adults -arthritis
–in chronic hemolytic anemia -aplastic crisis
–in immunodeficiency -chronic anemia
Term

Chickenpox

- what microbe causes it

- 2 methods of spread

Definition
varicella-zoster virus
spread via direct contact or respiratory secretions
Term
Describe progression of the rash in chickenpox
Definition
–progresses cephalocaudally (head->down)
–papules, vesicles and crusted lesions (different stages) all present at the same time
Term
How to diagnose chickenpox (via a lab) besides the usual detection of IgM antibodies or fourfold rise in IgG  antibodies
Definition
Tzanck smear
Term

Treat chickenpox with ___

 

Definition
acyclovir -oral or IV
Term
Prevent chickenpox with ___
Definition
live attenuated virus vaccine
Term
List some possible complications of chickenpox (8 in all)
Definition
–bacterial cellulitis
–thrombocytopenia
–arthritis
–encephalitis or meningitis
–hepatitis
–glomerulonephritis
–pneumonia
–fetal infection
Term
3 drugs to treat shingles (herpes zoster) and why you would want to treat it
Definition
–intraveneous acyclovir
–valacyclovir orally
–famciclovir orally

***prevents post-herpetic neuralgia***
Term

Smallpox

- microbe that causes it

- how spread

Definition

variola virus


spread via respiratory droplets

Term
Describe the progression of smallpox before the rash appears
Definition

1-2 days fever and myalgia

 

then 12-14 day incubation

Term

Give the 4 step progression for the features of the smallpox rash

 

Give the 5 steps of spread of the rash (what parts of the body)

Definition

papules -> vesicles-> pustules ->scabs (all lesions look the same at the same time)

 

mouth->face->arms->trunk->legs

Term
How to treat smallpox (2)
Definition

vaccine within 4 days of exposure (lessens or prevents illness)


cidofovir active in vitro

Term
How to proceed if smallpox is suspected (2)
Definition
notify health department
isolate patient and garments
Term
How to treat herpes "cold sore"
Definition
topical penciclovir
Term
How to treat cutaneous herpes infection
Definition
cutaneous herpes -oral valacyclovir or
IV acyclovir
Term
2 specific viruses that cause hand, foot, and mouth disease
Definition
–coxsackievirus A16
–enterovirus 71
Term

Molluscum contagiosum

- what microbe causes it

- how spread

- what it looks like

Definition
- unclassified poxvirus
- spread by direct contact (can spread like crazy in AIDS)
- discrete, papular, waxy skin lesions with central umbilication
Term
How to diagnose Molluscum contagiosum
Definition
clinical + see intracytoplasmic inclusions
Term
How to treat Molluscum contagiosum
Definition
Remove the lesions
Term
First disease is aka ___
Definition
measles
Term
Second disease is aka ___
Definition
rubella
Term
Third disease is aka ___
Definition
scarlet fever
Term
Fourth disease is aka ___
Definition
Scarlet Fever from Staph. or Boston Fever from enterovirus
Term
Sixth disease is aka ___
Definition
roseola
Supporting users have an ad free experience!