Shared Flashcard Set

Details

Immunosuppressants
Immuno
9
Pharmacology
Graduate
06/05/2013

Additional Pharmacology Flashcards

 


 

Cards

Term
cyclosporin
Definition
binds calcineurin, inhibits IL-2, decreases T cell activation.
constricts afferent and efferent arterioles.
Term
tacrolimus
Definition
binds FKBP, decreases IL-2, decreases T cell activation.
nephrotoxic and neurotoxic
Term
azathioprine
Definition
can't make purines.
bone marrow suppression.
metabolized by xanthine oxidase.
Term
muromonab
Definition
targets CD3, kills all T cells
Term
daclizumab
Definition
targets IL-2 receptor, CD25
Term
mycophenalate mofetil
Definition
inhibits IMP dehydrogenase, can't make guanine.
lymphoma
Term
omalizumab
Definition
targets IgE
Term
sirolimus
Definition
binds FKBP, inhibits mTOR, inhibits T cell proliferation
Term
thalidomide
Definition
anti-angiogenic. affects TNF alpha.
phocomelia.
Supporting users have an ad free experience!