Term
| What is the goal of the immune system? |
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Definition
| to defend against diseases in the blood system |
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Term
| What cells are involved in the immune system? |
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Definition
Neutrophils Lymphocyts eosinphils monocytes besophils
NLMEB |
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Term
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Definition
| Neutrophils Lymphocytes Monocytes Eosinophils Besophils |
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Term
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Definition
| B cells T cells natural killer cells |
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Term
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Definition
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Term
| What are the central and peripheral lymphoid tissues? |
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Definition
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Term
| What is Humoral immunity? |
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Definition
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Term
| Who are the major players in Humoral Immunity? |
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Definition
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Term
| What is Cell-mediated immunity? |
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Definition
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Term
| Who are the major players in cell-mediaed immunity? |
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Definition
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Term
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Definition
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Term
| Who are the major players in innate immunity? |
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Definition
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Term
| What is adaptive immunity? |
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Definition
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Term
| Who are the major players in adaptive immunity? |
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Definition
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Term
| Who are the local police? |
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Definition
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Term
| How long till the local police take action? How strong are they? |
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Definition
| Immediate/Not very Strong |
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Term
| What is the complement system/cascade? |
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Definition
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Term
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Definition
| Membrace attack complex- pokes really big holes in the cell membrane (lysis) simmalir to perfornin which is like cytotoxic cells CD-8 |
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Term
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Definition
| an immunoglobulin molecule that reacts with a specific antigen that induced its synthesis and with similar molecules |
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Term
| What is the goal of the innate immune system? (Neutralize and opsonize) |
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Definition
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Term
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Definition
| Pathogen- Associated Molecular Patterns |
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Term
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Definition
| Pattern Recognition Receptors |
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Term
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Definition
| T cells (adaptive immunity) |
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Term
| How long does it take for the military to take action? How strong are they? |
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Definition
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Term
How does it accomplish this?
What is the first line of defense?
What is the second line of defense?
What is the third line of defense? |
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Definition
1st Line of defense : Skin / Mucus / Acid PH
2nd Line of Defense: NLMEB
3rd Line of Defense: Cells and Proteins |
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Term
| What are the 3 antigen presenting cells (APCs)? |
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Definition
DMB
Dendretic-Macrophage-BCEll |
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Term
Where are each of the antigen presenting cells found?
Select from: peripheral blood (circulation), lymphoid tissue, connective tissue, epithelia, and body cavities. |
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Definition
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Term
| How do they get antigen (Ag) for presentation? (hint: big eaters) |
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Definition
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Term
| What cell(s) do the APC present antigens (Ag) to? |
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Definition
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Term
| What is the process of APC activation and maturation? |
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Definition
§ Dendritic cells
§ B cells
§ Macrophages |
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Term
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Definition
| Major Histocompatibility Complex |
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Term
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Definition
| group of genes that code for proteins found on the surfaces of cells that help the immune system recognize foreign substances |
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Term
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Definition
| a marker that all cells have. also known as CD-8 |
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Term
| Where in the cell are the foreign substances coming from? (MHC-I) |
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Definition
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Term
| What type of T-cell does it bind to? |
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Definition
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Term
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Definition
| CD-4 (also known as T Helper cells) only DMB has this marker |
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Term
| Where in the cell are the foreign substances coming from? (MHC-II) |
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Definition
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Term
| What type of T-cell does it bind to? |
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Definition
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Term
| Which cells in the body do/do not possess MHC-I? MHC-II? |
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Definition
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Term
| What are T-lymphocytes (T-cells)? |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
What are the T cell functions?
TH1 |
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Definition
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Term
What is their action?
TH2 |
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Definition
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Term
| What are two (2) roles of TH1? TH2? What’s the timescale for such killing action to be initiated: minutes, hours, days, or weeks? |
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Definition
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Term
Do TH1 or TH2 cells activate macrophages? Which of the two inhibit macrophage activation?
Tc |
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Definition
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Term
| What are the three (3) mechanisms by which CTLs kill? |
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Definition
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Term
| Do CTL's kill non-specifically or directional? |
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Definition
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Term
| What’s the timescale for CTL killing action to be initiated: minutes, hours, days, or weeks? |
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Definition
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Term
What are perforins and what do they do?
(CD4 or CD8) |
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Definition
| CD-8 They cause lysois (cell death) |
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Term
| Which T cells are CD4? CD8? |
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Definition
CD-8 is T6
CD-4 is T helper Cells |
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Term
| Which MHC complex does CD 4 interact with? CD8? |
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Definition
MHC 1 is with Cd-8
MHC 2 is with CD-4 |
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Term
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Definition
| do not attack invading organisms directly but instead destroy the body’s own cells that have either become cancerous or been infected with a virus |
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Term
| What are B-lymphocytes (B-cells)? |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| Who are B cells dependent on for activation? |
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Definition
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Term
| What do B cells become when they secrete antibodies? |
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Definition
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Term
| What are the four signs of inflammation? |
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Definition
Heat
Redness
Pain
Swelling |
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