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Immunology
Immune System
25
Biology
Undergraduate 4
04/02/2009

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Cards

Term
Origin of T lymphocytes
Definition
Bone Marrow Stem cells
Term
Where do T lymphocytes differentiate?
Definition
thymus
Term
How do mature T lymphs leave the thymus?
Definition
Blood
Term
Is the Thymus a primary or secondary lymph organ?
Definition
Primary
Term
Where is the thymus located
Definition
anterior thorax(above the heart)
Term
What does the thymus contain
Definition
immature T cells
Term
Does lymph recirculate into the thymus
Definition
no it never goes back
Term
Epithelial cells in the thymus from the ectoderm form
Definition
The cortex
Term
Epithelial cells from endoderm form
Definition
medulla
Term
ectoderm and endoderm form what
Definition
thymic anlage
Term
as t cells mature where do they move from to where
Definition
subscapsular region of the cortex to medulla
Term
The thymic anlage is colonized by
Definition
bone marrow stem cells
Term
what gives rise to T cells and dendritic cells?
Definition
bone marrow stem cells
Term
Bone marrow derived macrophages colonize where and concentrate in the
Definition
thymus & medulla
Term
Failure of thymus to develop T cells is called
Definition
DiGeorge's Syndrome
Term
Thymus is active in the
Definition
very young
Term
When does the thymus stop increasing in size?
Definition
Puberty
Term
what replaces your thymocytes as you get older?
Definition
Fat involution
Term
T cells are short-lived or long lived?
Definition
long lived
Term
Progenitor cells enter the thymus lacking what structure found on mature T cells
Definition
Cell surface glycoproteins
Term
T cell receptor genes are located where?
Definition
germline configuration
Term
Cells express what adhesion molecule in ~1 week
Definition
CD2
Term
What leads to expression of CD44 then CD25?
Definition
Maturation
Term
What are the two classes of T cell receptors?
Definition
alpha/beta gamma/delta
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