Term
The following results are from a rubella titer performed on acute & convalescent sera using a 2-fold serial dilution:
Acute serum titer: 1:8
Convalescent serum titer: 1:32
After evaluating the above results, the best interpretation is: |
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Definition
| Results are consistent with active infection with rubella |
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Term
| Which of the following describes an antigen-antibody reaction? |
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Definition
| The reaction is reversible |
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Term
| In the interpretation of agglutination tests for febrile diseases, which of the following is of the greatest diagnostic important? |
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Definition
| Rise in titer of the patient's serum |
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Term
| The strength of a visible reaction is known as: |
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Definition
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Term
The following pattern of agglutination was observed in an antibody titration is due to:
TUBE 1 2 3 4 5 6 7 8 9
Result 1+ 2+ 4+ 4+ 3+ 3+ 2+ 1+ 0+ |
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Definition
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Term
| The genus of virus associated with anogenital warts, cervical dysplasia, & neoplasia is: |
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Definition
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Term
| Respiratory syncytial virus is best isolated using a: |
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Definition
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Term
| Virus transport medium containing antimicrobial agents is used to collect & transport specimens for viral culture because this medium: |
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Definition
| Inhibits bacterial and fungal growth |
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Term
| Hepatitis C differs from hepatitis A because it: |
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Definition
| Is associated with a high incidence of the chronic carrier state |
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Term
| What assay would confirm the immune status to hepatitis B virus? |
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Definition
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Term
| Which of the following is the best indicator of an acute infection with the hepatitis A virus? |
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Definition
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Term
| Cells known to be actively phagocytic include: |
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Definition
| Neutrophils, Eosinophils, Monocytes |
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Term
| Non-specific killing of tumor cells are carried out by |
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Definition
|
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Term
| Which of the follwing mediators is released during T-cell activation |
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Definition
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Term
| A DPT vaccination is an example of |
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Definition
| Active humoral-mediated immunity |
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Term
| Cells that are precursors of plasma cells & also produce immunoglobulins are |
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Definition
|
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Term
| The immunoglobulin classes most commonly found on the surface of circulating B lymphocytes are |
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Definition
|
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Term
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Definition
| Secretion of immunoglobulins |
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Term
| T lymphocytes are incapable of functioning as |
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Definition
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Term
| T lymphocytes that possess the CD8 surface marker mediate with the following T-cell functions |
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Definition
|
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Term
| In flow cytometry, labeled cells |
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Definition
| Scatter the light and Emit Fluorescence |
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Term
| In laser flow cytometry, applying voltage potential to sample droplets as they stream past the light beam & using charged deflector plates results in |
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Definition
| The separation of cells into subpopulations based on their charge |
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Term
| What is the immunologic method utilized in the flow cytometer? |
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Definition
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Term
| HLA B27 antigen has been associated with which of the following diseases? |
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Definition
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Term
| A concentrate of lymphocytes can be prepared from peripheral blood by |
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Definition
| Density gradient centrifugation |
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Term
Given the following data:
WBC = 5x10^3/uL
Lymphs=15%
CD4=8%
Calculate the absolute CD4 |
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Definition
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Term
Refer to the following results for peripheral blood samples:
% T cells
Patient #1 85%
Patient#2 23%
Patient#3 51%
Patient#4 82%
Normal control 44% |
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Definition
| Normal control is too low and another sample should be selected |
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Term
| Antibodies composed of IgG immunoglobulin |
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Definition
| Can cross the placenta from mother to fetus |
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Term
| Antibody class & subclass are determined by major physiochemical differences & antigenic variation found primarily in the |
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Definition
| Variable regions of heavy and light chains |
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Term
| The ratio of kappa to lambda light chain producing cells in normally individuals is |
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Definition
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Term
| Treatment of IgG with papain results in how many fragments from each immunoglobulin molecule? |
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Definition
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Term
| Which of the following immunoglobulins is the most efficient at agglutination |
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Definition
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Term
| "A monoclonal spike of IgG, Bence Jones proteinuria, & bone pain are usually associated with:" |
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Definition
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Term
| Patients suffering from Waldenstrom macroglobulinemia demonstrate excessively increased concentrations of which of the following? |
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Definition
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Term
| Which of the following is a true statement about Bruton agammaglobulinemia disease? |
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Definition
| There are decreased to absent concentrations of Igs |
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Term
| Which of the following is the recognition unit in the classical complement pathway? |
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Definition
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Term
| Potent chemotactic activity is associated with which of the following components of the complement system? |
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Definition
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Term
| Which of the following is most likely to activate the alternative pathway of complement activation? |
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Definition
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Term
| "Hereditary deficiency of early complement components (C1, C4, C2) is associated w/:" |
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Definition
| Lupus erythematosus like syndrome |
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Term
| A child has severe hay fever. A total IgE measurement was performed by the Ouchterlony immunodiffusion method. No lines of precipitation appeared on the immunodiffusion plate. The most likely explanation is: |
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Definition
| IgE is in too low concentration to be detected by this method |
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Term
| The most rapid immediate hypersensitivity reaction is associated with: |
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Definition
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Term
| Anti-RNA antibodies are often present in individuals having an anti-nuclear antibody immunofluorescent pattern that is: |
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Definition
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Term
| Rheumatoid factor reacts with: |
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Definition
| Gamma globulin-coated particles |
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Term
| Which of the following terms describes a graft between genetically unidentical individuals belong to the same species? |
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Definition
|
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Term
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Definition
| Is useful in screening for Syphilis |
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Term
| "A VDRL serum sample is heat invactivated, then placed in a refrigerator for overnight storage. Before being tested, the serum must be:" |
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Definition
| Reheated to 56 degrees Celsius for 10 minutes |
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Term
| A request is received in the laboratory for assistance in selection the appropriate test(s) for detecting Lyme disease. Which of the following would be suggested? |
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Definition
| The MO is difficult to isolate and ABY titers will provide the most help |
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Term
| An example of a live attenuated vaccine used for human immunization is: |
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Definition
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Term
The best interpretation for the following observed cold agglutinin titer results is:
Tube# 1 2 3 4 5 6 7 8 9 10
dilution 1:1 1:2 1:4 1:8 1:16 1:32 1:64 1:128 1:256 1:512
4C + + + + + + + + 0 0
37C 0 0 0 0 0 0 0 0 0 0 |
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Definition
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Term
| "The best method to detect infections due to rubella, Epstein-Barr and human immunodeficiency viruses is:" |
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Definition
| Antibody detection by EIA |
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