Term
| MHC II are in _______ cells and are recognized by ___+ T cells and protect against _________ pathogens |
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Definition
Immune Cells, CD4, extracellular.
Has 2 transmembranes |
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Term
| MHC I are in _______ cells and are recognized by ___+ T cells and protect against __________ pathogens |
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Definition
All cells, CD8, intracellular.
Contains B microglobulin and one transmembrane |
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Term
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Definition
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Term
| Secondary Lymphoid organs |
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Definition
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Term
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Definition
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Term
| Flow of lymph starting at capillaries |
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Definition
| Capillarie -> interstitial fluid -> lymph vessels -> afferent lymph vessel -> lymph node -> efferent lymph vessel -> lymphatic trunk -> thoracic duct -> vena cava |
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Term
| Classicial pathway initiation |
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Definition
Antigen/antibody complexes
IgM |
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Term
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Definition
| Lectin binding to pathogen surface |
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Term
| Alternative pathway initiation |
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Definition
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Term
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Definition
| Hematopoietin, activates T cells, proliferates |
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Term
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Definition
| Hematopoietin, B cell activation |
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Term
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Definition
| Interferon, increase MHC I, digest dsRNA |
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Term
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Definition
| Tumor necrosis factor, leukocyte recruit, fever |
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Term
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Definition
| tumor necrosis factor, kills cells |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| chemokine, neutrophil recruitment |
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Term
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Definition
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Term
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Definition
| when a single gene influences several phenotypic traits |
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Term
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Definition
| when multiple genes does what a single gene could not |
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Term
| Pro-inflammatory cytokines |
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Definition
| IL-1, IL-6, TNF, LTB, IL-12, IFN |
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Term
| Anti-inflammatory cytokines |
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Definition
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Term
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Definition
| 2 constant domains, 70% in blood |
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Term
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Definition
| 3 constant domains, 2nd most common, dimeric form, sweat, milk |
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Term
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Definition
| 3 constant domains, co expressed with IgM, located on naive B cells |
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Term
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Definition
| 4 constant domains, rare in blood, allergies, anti-helmenthic, mast cells |
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Term
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Definition
| 4 constant domains, pentameric form, located on naive B cells |
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Term
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Definition
| Associate with MHC II, regulatory cells, tall with 4 domains and 1 transmembrane |
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Term
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Definition
| Associate with MHC I, killer cells, primarily recognize virally infected cells, small with 2 side-by-side domains and 2 transmembranes |
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Term
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Definition
| MHC I, degradation occurs in cytosol, CD8, |
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Term
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Definition
| MHC II, CD4, degradation occurs in endocytic vesicles, |
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Term
| But Everybody Must Like Nancy |
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Definition
| Basophils < Eosinophils < Monocytes < Lymphocytes < Neutrophils |
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