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Immunizations
Chapter 36
80
Pharmacology
Graduate
05/13/2013

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Term
Name the live vaccinations
10 of them
Definition
Herpes zoster
Influenza
Measles
Mumps
Rubella
Rotavirus
Typoid oral
Varicella
Vaccinia (small pox)
Yellow Fever
Term
If two live vaccinations are not given on the same day, how long must you wait to give the second one?
Definition
4 weeks
Term
T/F
Inactivated vaccines, if not given on the same day, can be given on two consecutive days.
Definition
True
you can give inactivated vaccinations simultaneously or at any other interval even with other live vaccines.
Term
You can give live vaccinations to a pregnant lady.
Definition
NOPE
False
Term
You should not give live vaccinations to people who are immunosuppresed
Definition
True
Term
How many known serotypes of Stretococcal pneumonia exist?
Definition
90
Term
How many serotypes of streptococcal pneumonia are covered in a vaccine give to a child under age 2
Definition
13
Term
What is the maximum number of serotypes covered of stretococcal pneumonia vaccination
Definition
23
23-valent polysaccharide vaccine (pneumovax 23
Term
Who should get pneumovax?
Definition
Smokers 19-64 years old
all adults over 65
everyone 2 years of age with certain chronic diseases
Term
How much pneumovax should you give?
Definition
0.5 ml IM or SQ
Term
Prevnar is?
Definition
13-valent conjugated polysaccharide vaccine for streptococcal pneumonia
Term
What is the usual dose for Prevnar 12-15 month olds?
Definition
0.5 ml IM for 4 doses starting at 2 months old. The three other doses are usually given at 4,6 and 12-15 months old.
Term
What is the most dangerous strain of influenza?
Definition
influenza A
Term
Flu Mist you give how much?
Definition
0.1 ml in each nostril
Term
The tetanus vaccine is usually formulated with?
Definition
Diptheria and Pertussis
Term
What is the tetanus dose for a pediatic patient?
Definition
0.5 ml IM of DT or DTaP at 2,4,6 and 12-18 months
A booster is given at 4-6
Term
What is the adolescent dose of tetanus vaccine?
Definition
0.5 ml of Tdap given at 11-12 years old
Term
What is the adult dose of tetanus vaccine?
Definition
0.5 ml IM of Tdap
Term
Revaccination of tetanus is required how offten?
Definition
every 10 years with Tdap
Term
The "tetanus" portion of Tdap protects you from?
Definition
Clostridium tetani
a postive anaerobic rod
Term
The Diptheria portion of Td protects you from?
Definition
Corynebacterium diptheriae
aerobic gram positive
Term
The P "pertussis" portion of Tdap protections you from
Definition
Bordetella pertussis
aerobic gram negative rod
whooping cough
Term
How is hepatitis B transmitted?
Definition
Exposure to body fluids by pareenteral or mucosal contact.
hep B is sexually transmitted!
Term
Hep B vaccine is produced using recombinant DNA technology. T/F
Definition
True
It was the first vaccine made this way
Term
What is the dose of the Hep B vaccine?
Definition
Peads 0.5 ml given at BIRTH, 2 months and 6 months
Adolescents 11-15 may get two dose series separated by 4 months only approved for Recombivax HB
Term
What are the two products for Hep B vaccination?
Definition
Recombivax HB
Engerix-B
Term
All individuals should receive a booster of Heb B at 18 years of age
Definition
FALSE
no booster is required and should not be given
Term
How many different types of Haemophilus influenzae exist?
Definition
six, a-f
Term
Which type of haemophilus influenza causes 95% of disease?
Definition
Type B
Term
What age group are most likely to get H. Flu infection?
Definition
children, peak 6-7 months
Term
ActHIB and PedvaxHIB are indicated for who?
Definition
infants >6 weeks of age.
Doses given before 6 weeks may inhibit the production of antibodies to subsequent doses and is therefore contraindicated
Term
Hiberix is indicated for?
Definition
the booster at 15 months to 4 years old ONLY
Term
what is the dosing schedule for the H.flu vaccine?
Definition
0.5 ml IM given at 2, 4, and 6 months if using ActHIB

0.5 ml at 2,4 months if PedvaxHIB is used
Term
What is COMVAX
Definition
a combination of Hib vaccine and hepatitis B vaccine. cannot be given before 6 weeks old
Term
Hep B is a ___ virus?
Definition
DNA
Term
Hep A is a ___ virus?
Definition
RNA
Term
How is Hep A transmitted?
Definition
fecal to oral route
Term
Havris and VAQTA are vaccinations to protect you from?
Definition
Hep A
both products are available in pediatric and adult formulations
Term
Hep A vaccine is indicated for:
Definition
all high risk patients
routinely for all children 1-2 years of age
Term
What doses and schedules should children and adolescents receive for Hep A?
Definition
0.5 ml repeated in 6-12 months (Havrix)
0.5 ml repeated in 6-18 months (VAQTA)
both 2 total doses
Term
Adults should receive what schedule of HepA
Definition
1 ml repeated in 6-12 months, two total doses.
Term
Twinrix contains?
Definition
Hep B (adult dose) and hep A (pediatric dose)
Term
Twinrix is indicated for?
Definition
people >18
Term
What is the dosing schedule for Twinrix?
Definition
1 ml given 0,1, and 6-12 months
Term
What is the accelerated schedule for Twinrix?
Definition
1 ml given 0, 7 days and 21-30 days.
Booster at 1 year
Term
Menomune protects you from
Definition
Neisseria meningidtis
gram negative bacteria with a polysaccharid capsule
Term
Menomune protects you from what strains?
Definition
A, C, W-135, and Y of N. Meningidtis
does not cover against B which is a common cause of infection
Term
What is the dose of menomune?
Definition
0.5 ml SQ,
booster in 3-5 yeras if exposure continues
Term
Who should get the vaccine?
Definition
military personnel
freshmen in college living in dorms
asplenia
traveling to the "meningitis belt" - Sub-Saharan africa
Term
Menactra protects you from
Definition
Neisseria meningitis, this is conjugated and effective against serotypes A, C, W-135, Y
Missing B AGAIN
Term
Menactra is approved for use in:
Definition
2-55
Term
Menveo protects you from?
Definition
N. Meningiditis serotypes A, C, W-125, Y AGAIN missing B
it is conjugated as well and recently approved for infants, but it isn't recommended for routine use
Term
Menactra and Menveo whould be given?
Definition
0.5 ml IM for two doses
Term
Poliovirus is transmitted?
Definition
person to person through fecal-oral route
Term
the only vaccine available in the US is IPOL, inactivated trivalent injectable vaccine?
Definition
Yes, the oral polio vaccine was discontinued in US due to elimination of wild-type polio disease.
Term
What is the dose and schedule for IPOL?
Definition
0.5 ml IM given at 2,4,6-18 months and 4-6 years of age.
Routine booster not recommended unles traveling to an endemic area
Term
Measles is a viral infection with the main presentation being a maculopapular rash.
True or false
Definition
true
Term
Measles is highly contagious and transmitted through fecal oral contact. True or False
Definition
False
it is highly contagious and transmitted through large respiratory droplets
Term
Mumps is a viral infection with a presentation of parotitis in 30-40% of cases.
Definition
True
Parotitis is swelling of the partoid gland (major salivary gland)
Term
rubella is a bacterial infection
Definition
False
all of the MMR are viral!
Term
All transmission of MMR is through respiratory droplets.

True or false
Definition
true
Term
MMRII should dosed
Definition
0.5 ml Im give at 12 months of age and seoncd dose is recommended at age 4-6 years old
Term
MMRII vaccine is safe in pregnancy?
True or False
Definition
False
the MMRII vaccine is contraindicated in pregnancy and should be avoided for 4 weeks following the vaccination.
Term
Transmission of varicella is person to person skin contact?
Definition
FALSE
it is through infected respiratory secretions... who knew
Term
Transmission of herpes zoster is by direct contact with nonimmune person.
Definition
True
Term
Varivax is the varicella vaccine and is dosed
Definition
0.5 ml IM given at 12-18 months of age
A second dose is recommended at 4-6 years old

Adult dose (>13yo): 0.5 ml two doses separated by 4-8 weeks
Term
what is the dose of herpes zoster (zostavax) vaccine?
Definition
0.65 ml Sq
Term
Rotavirus is transmitted by what route?
Definition
fecal-oral route, close person to person contact, and fomites
Term
Herpes zoster vaccine is indicated in?
Definition
all people over 60 years of age
Term
RotaTeq is a vaccine that covers?
Definition
Rotavirus
Pentavalent human-bovine reassortant rotavirus vaccine
Term
Rotarix vaccine covers?
Definition
Rotavirus
Monovalent human rotavirus vaccine
Term
Which must be reconstituted, RotaTeq or Rotarix?
Definition
Rotarix
Term
Both rotaTeq and Rotarix are orally administered and contain a live virus?
Definition
True
Term
RotaTeq is a three dose serious and Rotarix is a 2 dose series
Definition
True
Term
HPV Type 16 and 16 cause 70% of all genital warts.

True or false
Definition
False
16 and 18 cause 70% of all cervical cancers
Type 6 and 11 cause 90% of all genital warts
Term
Gardasil protects from what types of HPV?
Definition
6,11,16,18
all 4
Term
Cervarix protects from what types of HPV?
Definition
16 and 18
cancer causing strains
Term
HPV vacines are indicated in who?
Definition
all women age 9-26 years of age and should be given routine to all 11-12 year old girls
Term
Which HPV vaccine is indicated in males?
Definition
Guardisil
ages 9-21
Term
Both Gardasil and Cervarix are given how?
Definition
0.5 ml IM at 0, 2, and 6 months
0 being staring date, not birth duh...
and the vaccine must be shaken
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