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Immunity
ppt presentation
83
Nursing
Not Applicable
05/21/2024

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Term
Function of immune system
Definition
protect body from foreigh antigens, identify and destroy potentially harmful cells, remove cellular debris
Term
hypersensitivity is
Definition
overreaction of immune system
Term
autoimmune disorder is when immune system _
Definition
attacks own body
Term
immunodeficiency is
Definition
incompetnet immune system
Term
Immune system performs several functions
Definition
defends and protects body from infection, removes and destroys dead/damaged cells, identifies and destroys malignant cells
Term
Natural immunity includes
Definition
physical barriers, chemical barriers, leukocyts, inflammatory response
Term
Nonspecific repsonses of the immune system:
Definition
prevent and limity entry of invaders, limit tissue dmage, reduce immune system workload
Term
example of nospecific immune response
Definition
inflammation
Term
activated when inflammatory process cannot destroy invaders
Definition
specific response
Term
stimulate the inflammatory response and offer protection against various types of infection and foreign antigens.
Definition
WBCs or leukocytes
Term
Five types of WBCs
Definition
neutrophils, lymphocytes, monocytes, eosinophils, and basophils— used in laboratory analysis
Term
normal Leukocyte level
Definition
4,500–10,000 cells/mm3
Term
Leukocytoisis (>10,000) can indicate:
Definition
indicate inflammation, infection, some malignancies, trauma, dehydration, stress, steroid use, and thyroid storm.
Term
decrease in number of circulating leukocytes
Definition
leukopenia
Term
Leukopenia occurs when:
Definition
bone marrow activity is supressed, when leukocyte destruction increases
Term
Neutrophils make up about _ of white blood cell population
Definition
50%
Term
respond first to bacterial or viral infection and alert other immune system cells to respond.
Definition
neutrophils
Term
Percentage and numuber of circulating neutrophils is used to measure:
Definition
a client's risk for infection
Term
fight pathogens, create manifestation in response ot allergens
Definition
esoinophils
Term
eosinophils are related to
Definition
hypersensitivity reactions
Term
Produce a response to allergens and other pathogens by releasing histamine and other biochemicals that can cause inflammation
Definition
Basophils
Term
largest leukocytes
Definition
monocytes
Term
monocytes mature into
Definition
macrophages
Term
Originate in myeloid, lymphoid cell lines
Definition
Dendritic cells
Term
Dendritic cells operate in:
Definition
most organs
Term
specialized dendritic cells in skin
Definition
langerhans
Term
WHen dendritic cells become to tolerant it can create an environment for
Definition
chronic infection
Term
Mature in thymus & have a specific immune response
Definition
T- lymphocytes
Term
On contact with APCs (antigen rpesenting cells) T-lymphoctes mature into
Definition
active helper T cells, cytotxic T cells, memory T cells
Term
Mature in bone marrow & have a specific immune response
Definition
B-lymphocytes
Term
ON contact with antigen, B-lymphoctyes are activated and mature into:
Definition
plasma cells and secrete antibodies or memory cells
Term
Natural killer cells are activated by _ and released by
Definition
cytokines; T-cells
Term
Natural killer cells are located in
Definition
spleen, lymph nodes, bone marrow, blood
Term
Antibodies are produced in response to an antigen.
Definition
Active immunity
Term
Active immunity provides _ immunity
Definition
permanent
Term
Active immunity involves:
Definition
B and T- lymphocytes
Term
Active immunity produces specific antibodies against
Definition
specific antigens
Term
Antibodies are produced by an external source.
Definition
passive immunity
Term
passive immmunity is _ immunity that does not have _ of past exposures
Definition
temporary; memory
Term
the body's first line of defense
Definition
intact skin
Term
passive immunity includes
Definition
Mucous membranes, secretions, enzymes, phagocytic cells, and protective proteins
Term
Classes of antibodies
Definition
IgM, IgG, IgA, IgD, IgE
Term
Igm is responsibel for
Definition
primary immunity
Term
IgG is a major:
Definition
immunoglobulin
Term
IgA: protects;
Definition
mucous membranes
Term
IgD has a role in
Definition
regulation of cells and nasopharyngeal cavity
Term
IgE increases during
Definition
allergic reactions, anaphylaxis
Term
Cell mediated immunity attacks antigens directly bye
Definition
activating B cells
Term
In primary immune response _ cell produces antibodies to eliminate extracellular antigens
Definition
B
Term
In primary immune response antibodies _
Definition
react specifically to that antigen
Term
Primary immune response takes
Definition
3 days
Term
Subsequent encounters with an antigen trigger memory cells
Definition
secondary immune response
Term
recovers proteins for vascular system and protects blood stream from invading organisms
Definition
lymphoid system
Term
Lymph nodes filter _
Definition
foregin products or antigens
Term
produces and stores hematopoetic stem cells
Definition
bone marrow
Term
Lymphoid tissues diffuse collections of
Definition
lymphocytes, plasma cells, phagocytes
Term
secreted to coat mucosal cells and prevent bacteria attachment
Definition
IgA
Term
protect from inhaled, ingested, foreign agents
Definition
tonsils and adenoids
Term
largest lymphoid organ that filters blood
Definition
spleen
Term
Two kinds of spleen tissue
Definition
white pulp, red pulp
Term
white pulp involves
Definition
lymphoid prliferation, immune serveilance
Term
red pulp involves
Definition
blood filtration, removes debris, foreign matter from blood
Term
stores blood and breakdown products of RBCs for future use
Definition
spleen
Term
during fetal life and childhood _ is the site for maturation and dfferentiation of thymic lymphoid cells
Definition
thymus glad
Term
thymosis stimulates:
Definition
lymphopoiesis
Term
refers to neutrophils and macrophages and their work as phagocytes
Definition
Nonspecific immunity
Term
eat and destroy microorganisms, thereby helping to protect the body from harm
Definition
phagocytes
Term
both _ are releasd during the inflammatory response
Definition
neutrophils
Term
Hypersensitivity reactions
Definition
type I, Type II, Type III, Type IV
Term
Type I hypersensivitity
Definition
immediat hypersensitivey
Term
Type II hepersensitivity
Definition
cytotoxic hypersensitivity
Term
Type III hypersensitivity
Definition
immune conmplex reaction
Term
Type IV hypersensitivity
Definition
delayed-type hypersnesitivity
Term
Immune system loses ability to distinguish self from other and attacks own body
Definition
autoimmune diseases
Term
Transplant reactions
Definition
hyperacute rejection, acute rejection, chronic rejection
Term
hyperacute rejection occurs
Definition
minutes or hours after transplantation
Term
acute rejection occurs
Definition
weeks after transplantaion
Term
chronic rejection occurs
Definition
months after transplantation
Term
Primary immun deficiences are
Definition
congenital
Term
Secondary immune deificiencies typically result from
Definition
trauma, stress, cancer therapies, AIDS resulting from HIV
Term
The only immunoglobulin that crosses placenta
Definition
IgG
Term
maternal IgG disappears by
Definition
6 to 8 months
Term
Cell-mediated immunity acheives full function _
Definition
early in life
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