Term
| antibody-mediated defense |
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Definition
| defends against FREE viruses and bacteria in bodily fluids |
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Term
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Definition
| defends against abnormal cells-cancer transformed cells, viral cells, foreign cells |
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Term
| what are the 3 stages of both defense types |
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Definition
1.antigen encounter and recognition by lymphocytes
2.lymphocyte activation and clonal expansion
3.attack |
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Term
| what both humoral and cell mediated responses require? |
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Definition
| activation of helper T-cells |
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Term
| type of immunity when antibodies are transferred to from a person to another person |
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Definition
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Term
| natural acquired passive immunity |
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Definition
| transfer of antibodies in breastmilks or placenta |
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Term
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Definition
| administration of anitboooodies to combat infection, like a vaccine |
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Term
| type of immunity when antibodies were produced in response to antigens |
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Definition
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Term
| type of immunity when antibodies that develop in response to antigens |
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Definition
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Term
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Definition
| develops after administration of antigen to prevent disease. |
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Term
| type of immunity the develops after exposure to antigens in environment |
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Definition
| naturally acquired ACTIVE immunity |
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Term
| 4 properties of acquires (specific_ immunity) SVMT |
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Definition
| specificity, versatility, memory, tolerance. |
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Term
| what are the 2 types of lymphocytes? |
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Definition
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Term
| T lymphocytes:where do they mature, and what are the three types |
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Definition
| cytoxic T cells, helper T cells, suppressor T cells |
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Term
| B lymphocytes-where do they mature, and what cells do they give rise to |
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Definition
| Bone marrow, antibody secreting plasma cells |
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Term
cytotoxic T cells
1.effectors for cells mediated or humoral response?
2.what type of cells do they attack?
3. type of receptor? |
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Definition
1. cell mediated
2.infected/transformed cells
3.CD8 |
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Term
helper T cells
1.regulatory function in cellbody mediated, humoral, or both?
2.type of receptor |
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Definition
1.both
2. CD4(t4) receptor |
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Term
| suppressor T cells-function? |
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Definition
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Term
| B cells-carry out cell mediated or humoral immunity |
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Definition
| humoral aka antibody mediated |
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Term
T cell receptors
1.how many chained protein
2.what does this receptor need on the antigen to bind to it |
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Definition
1.2 chains
2.the antigen must be complexed to an MHC "self" protein |
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Term
B cell receptors
1. what is attached to the cell
2.what is Ig a copy of that the cell can produce? |
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Definition
1.Immunoglobulin-Ig
2.Ig is a copy of an antibody |
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Term
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Definition
| maturation of immune cells to do WORK son! |
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Term
| when do lymphocytes acquire the ability to "recognize" antigens? how is this process determined. ALso, what two traits does this give to the immune system |
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Definition
when lymphocytes acquire receptors specific to THAT antigen.
it is determined by genetics
it makes the immune system versatile, and specific |
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Term
| another name for antigenic determinants |
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Definition
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Term
| what are antigenic determinants/epitopes |
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Definition
| sites where antibodies bind to on the antigen..and "active site" if you will... |
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Term
| what type of lymphocytes secrete Antibodies |
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Definition
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Term
| on antibodies, what region is involved in the effector mechanism |
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Definition
| the constant ends (bottom of the Y) |
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Term
| on antiboooooodies, which end binds antigens |
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Definition
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Term
| the typical antibody, it can cross placentas, Ab (80%) |
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Definition
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Term
| antibody involved in alergic responses |
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Definition
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Term
| antibody that we don't have a fucking clue about |
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Definition
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Term
| antibody that is 1st to appear after Ag |
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Definition
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Term
| antibody in saliva, tears,l colostrum, breasteseses milkss |
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Definition
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Term
| what do histocompatibility proteins identify |
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Definition
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Term
MHC class 1
1. on what cells
2.recognized by what immune cell
2. what type of receptor does that immune cell have |
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Definition
1. on all cells
2.cytotoxic T cells
3. CD8 receptors |
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Term
MHC class II
1. on what cells
2. what are those^ cells called?
3. the other 1 cell that recognizes it |
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Definition
1. macrophages, B cells, dendritic cells
2. APCs:Antigen presenting cells
3. Helper T cells (CD4 Receptors) |
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Term
| infected cells present their antigen to which cells? |
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Definition
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Term
| APCs present their antigen to whom? |
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Definition
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Term
| 3 events required for activating Tcells |
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Definition
1.presentation of antigen bound to class II MHC protein to the APC
2.costimulation, binding of non antigenic proteins on APC and helper T-cell
3.APC secretes cytokines that help helper tcell |
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Term
| two cytokines released by helper Tcell after antigen presentation |
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Definition
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Term
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Definition
| promotes inflammation, fever, and sepsis |
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Term
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Definition
-it stands for "tumor necrosis factor"
-promotes apoptosis |
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Term
| write out the antibody mediated immune response mechanism |
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Definition
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Term
| for humoral response are the effector mechanisms specific or non specific. |
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Definition
| non specific-like the MAC mech |
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Term
| what cells produce a more rapid and amplified response if the same antigen is encountered again? |
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Definition
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Term
| giardia is attacked by which response system? |
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Definition
| cell mediated, since it is a virus that attacks other cells that have become infected. |
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Term
| what cells carry out the cell mediated response mainly? which receptor does this cell have? |
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Definition
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Term
| what is the ONLY thing that cytoxic T cells respond to |
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Definition
| antibooooodies on OUR OWN infected cells. aka antigenic determinant |
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Term
| infected cells present the antigenic determinant on which MHC class receptor? |
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Definition
| MHC CLASS 1. fucking remember it. |
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Term
| a macrophage well present an antigen to Helper T cells with which MHC class protein |
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Definition
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Term
| once a macrophage activates a helper T cell, what does the T(h) cell do to the cytotoxic t cell |
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Definition
| it activates the cytoxic t Cell with cytokines (like IL-2) for clonal expansion |
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Term
| write the cell mediated response mechanism |
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Definition
| don't fucking bitch JUST DO IT |
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Term
| what protein is used by cytotoxic T cells to destroy other cells |
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Definition
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Term
| for the cell mediated response, what cells "roam" the tissues and destroy any mutant cells that display a processed antigen |
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Definition
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