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Immune responce
first test
23
Pathology
Undergraduate 1
01/25/2013

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Cards

Term
Foreign host that enter the body are reconized by?
Definition
  • neutrophils
  • lymphocytes
  • macrophages
Term
This type of immunity is present at birth. It attacks non-self pathogens, does not distinguish among different types.
Definition
Innate Immunity
Term
What are the cells of innate immunity?
Definition
  • Neutrophils
  • Macrophages
  • Dendrite
  • Natural killer
Term
These are first responders, phagocytic, release proteases, cytokins(messenfers that coordinate immune and inflammatory responce)
Definition
Neutrophils
Term
These are phagocytic, Active adaptive immunity, becomes antigen presenting cell, enhances inflammation, active in healing.
Definition
Macrophages
Term
APC engulf invader to show to lyphocyte
Definition
Dendrite cells
Term
Undifferentiated lymphocytes, automatically kill foreign cells
Definition
Natural killer cells
Term
Series of 20 plasma protiens that promote and enhance immune/immplammatory functions- Activated by antigen or metabolic function of bacteria
Definition
Complement
Term
What does complement do?
Definition
  • Opsonization- coats bacteria to mark as invader
  • Chemotaxis- cytokines to attract immune/ inflammatory cells
  • Cell membrane attack complex- final event in complement
Term
Specific cell attacks specific antigen, devolopes after exsposure to the antigen.
Definition
Adaptive immunity
Term
Antibody protien in the blood that attacks the specific antigen
Definition
Humoral Immunity
Term
Phagocytic cells attack the specific antigen, T lymphocytes
Definition
cell-mediated immunity
Term
How do lymphocytes develope
Definition
Stem cells start, B cells mature in bone marrow, T cells mature in thymus, they then move to the lymph nodes to wait for an antigen presenting.
Term
The master regulator of the immune system
Definition
T helper cells (CD4)
Term
Killer cells, they are taught what specific cells to kill.
Definition
T cytotoxic cells (CD8)
Term
What tells the immune system what to attack
Definition
Antigen- presenting cell
Term
This is activated by CD4 to kill invaders?
Definition
CD8, & B cells
Term
What happens after B cells are activated?
Definition
They become plasma cells and release antibodies
Term
This creates antibodies that attach to an antigen to mark and destroy is.
Definition
plasma cells
Term
Why are antibodies created?
Definition
They are created to match the idenity characteristics on the antigen cell.
Term
What happens during primary immune responce
Definition
  • Macrophages engulf antigen-present to cd-4
  • cd-4 activates b cells
  • B cells produce antibodies
  • Plasma antibody levels rise
  • Vaccination produces primary immune response
Term
What happens druing secondary immune response
Definition
  • B memory respnd to antigen immediatley( no Cd-4 effect)
  • Plasma antibodies rise within a day
  • Booster shot
Term
All together how does body react to invaders?
Definition
  • Antigen enters body
  • phagocytes engulf
  • Shows to CD4
  • CD4 activates CD8
  • Activates B cell
  • Plasma cell/ memory cell make antibody
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