Term
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Definition
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Term
| What is the difference between Type I vs Type II IFNs |
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Definition
Type I - innate antiviral response induced by PAMPs
Type II - associated with Th1 adaptive immune response |
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Term
| Retroviral double stranded RNA is recognized by what TLR? |
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Definition
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Term
| Single stranded RNA is recognized by what TLR? |
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Definition
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Term
| Viral DNA is recognized by what TLR? |
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Definition
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Term
| What cells produce the most Type I IFN? |
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Definition
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Term
| The key effector cell in antiviral immune responses |
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Definition
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Term
| Which is associated with a sudden change, antigenic drift or shift? |
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Definition
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Term
| Which type of vaccine involves replication inside cells, attenuated or inactivated vaccines? |
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Definition
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Term
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Definition
| enhances the immune response to a vaccine, or influences the type of response that is induced |
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Term
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Definition
Recombinant proteins
Attenuation
Live recombinant
Polynucleotide (functional DNA) |
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Term
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Definition
| when pathogen-specific antibodies can be detected in serum |
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Term
| How do vaccines complicate serology |
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Definition
Can make it difficult to tell whether the animal seroconverted due to disease, or due to vaccine exposure.
-get around this by using vaccines that omits an antigen, so if you see antiobodies for that antigen you know it's bc the animal was diseased |
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Term
| 3 reasons vaccines need to be readminstered |
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Definition
1. competing with passive immunity;
2. to boost immunity;
3. to account for antigenic variation of pathogens over time) |
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Term
| Duration of immunity & when to give boosters |
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Definition
Distemper is <1 year
Rabies > 3 years
All others > 7 years |
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Term
| Ring vs predictive vaccination during an outbreak |
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Definition
Ring - create a barrier of vaccinated animals around an outbreak
Predictive - vaccinate the ones that are most likely to get sick (shipped animals, young etc) |
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Term
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Definition
-incorrect administration
-failure to respond
- |
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Term
| Animal size & adverse effect of vaccines |
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Definition
| more likely to occur in small dogs. but it is NOT recommended to reduce dosage for small dogs, not enough research behind how much is reqd for effective protection |
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Term
| Vaccine induced anaphylactic shock - treatment |
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Definition
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Term
| Why give killed vaccines to weims |
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Definition
| prone to osteodystrophy as a reaction to live distemper vaccines |
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Term
True or False
Ring vaccination and predictive vaccination are examples of prophylactic strategies |
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Definition
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