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IM - Infectious Diseases & Derm
Nova Orlando - Rotations
112
Health Care
Graduate
09/25/2011

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Cards

Term
MCC of CAP bacterial pneumonia
Definition
stretococcus pnuemoniae
Term
MCC of nosocomial pneumonia
Definition
gram negative rods and staph aureus
Term
penumococcal vaccine is recommended for who?
Definition
age 65 and older
Term
method to differentiate pneumonia and bronchitis
Definition
CXR
Term
atypical causes of CAP
Definition
mycoplasma
chlamydial pneumoniae
chlamydia psittaci
coxiella burnetti (Q fever)
legionella sp
viruses: influenza A & B, adenovirus, parainfluenza, RSV
Term
normal pulse in the setting of high fever is indicative of
Definition
atypical CAP
Term
alcoholic pneumonia
Definition
klebsiella
Term
nursing home pneumonia
Definition
pseudomonas
Term
HIV peneumonia
Definition
pneumocystis varinni and mycobacterium tuberculosis
Term
organ transplant pneumonia
Definition
legionella
Term
what classifies a good sputum specimen for pneumonia
Definition
> 25 PMNs and < 10 epithelial cells per low power field
Term
tset for legionella species
Definition
urinary antigen assay
Term
first line treatment for CAP < 60 yo
Definition
macrolides or doxycycline.
alt = flouroquinolones
Term
first line tx in CAP > 60yo and pts with co-morbidities
Definition
2nd/3rd generation cephalosporin.
alt = augmentin, 2nd generation macrolides and flouroquinolones.
Term
definition of lung abscess
Definition
one or more cavities, each > 2cm in diameter
Term
main risk factor for lung abscess
Definition
aspiration
Term
foul smelling sputum is indicative of
Definition
anaerobic infection
Term
MCC of death due to infection world wide
Definition
TB
Term
MCC of TB
Definition
mycobacterium tuberculosis
Term
secondary TB usually manifests where?
Definition
most oxygenated porton of the lung, apical/posterior segments
Term
radiographic findings in TB
Definition
Ghon's complex - calcified primary focus
Ranke's complex - calcified primary focus and calcified hilar lymph node
Term
classic CXR findings in TB
Definition
upper lobe infiltrates with cavitations,
Gohn complex and Rankes complex
Term
treatment of active TB
prophylactic tx for latent TB
Definition
active - INH + rifampin, pyrazinamide and ethambutol or steptomycin
prophylactic - isoniazid (INH)
Term
what consitutes a positve PPD reaction
Definition
normal population > 15mm
high risk > 10mm
HIV/immunocompromised > 5mm
Term
inability to fully extend knees when pt is uspine with hips flexed (90 degrees)
Definition
Kernig
Term
flexion of the legs and thighs that is brought on by passive flexion of the neck
Definition
Brudzinski's sign
Term
viral causes of meningitis
Definition
herpes (HSV-1)
arbovirus
enterovirus
less common - measules, mumps, EBV, CMV, VZV, rabies, and prion viruses
Term
most specific and sensitive test for diagnosing many various viral encephalitides
Definition
CSF-PCR
Term
imaging study of choice to dx encephalitis
Definition
MRI
Term
tx of HSV encephalitis
Definition
acyclovir for 2-3 weeks
Term
tx of CMV encephalitis
Definition
ganciclovir or foscarnet
Term
Hep B is associated with
Hep C is associted with
Definition
B = PAN
C = cyroglobulinemia
Term
transmission of the hepatitides
Definition
A and E = fecal oral
B = parenteral or sexual
C = parenteral
D = requires HBV
Term
HbsAg
Definition
acute or chronic infection
Term
HBeAg
Definition
active repilication and indicates infectivity
Term
anti-HBs
Definition
immunity
Term
anti-HCV
Definition
key marker of Hep C infection
Term
hepatitides that can progress to chronic disease
Definition
Hep B, C, D
Term
signs of hepatic encephalopathy (2)
Definition
asterixis, palmar erythema
Term
reservoir for botulism
Definition
home canned foods
Term
symmetric descending flaccid paralysis
Definition
botulism
Term
MCC of UTI
Definition
e coli
Term
MCC of UTI in sexually active females
Definition
staph saprophyticus
Term
UA with epithelial cells indicates
Definition
contamination from vulvar or urethral areas
Term
when do you tx asx bacteriuria
Definition
pregnancy or before urologic surgery
Term
tx of UTI
Definition
bactrim or ciprofloxacin x 3 days
Term
tx of UTI in men
Definition
treat for 7 days
Term
tx of recurrent UTI
Definition
if relapse occurs within 2 wks, continue tx for another 2 wks and get urine culture
Term
UTI prophylaxis
Definition
for pts who have > 2 UTI's/year
single dose of bactrim after sex or at first signs of infection
Term
clinical features of pyelonephritis
Definition
fever, chills
flank pain
symptoms of cystitis (frequency, urgency, burning, etc)
nausea, vomiting, diarrhea
Term
clinical features of pyelonephritis
Definition
fever, chills
flank pain
symptoms of cystitis (frequency, urgency, burning, etc)
nausea, vomiting, diarrhea
Term
MC STD
Definition
genital warts
Term
MC bacterial STD
Definition
chlamydia
Term
leading cause of infertilty in women
Definition
chlamydia due to tubal scarring
Term
tx of chlamydia
Definition
azithromycin
Term
tx of gonorrhea
Definition
ceftriaxone
also give azithromycin or doxycycline to tx chlamydia
Term
dx of HIV
Definition
screen = elisa
confirmation = western blot
Term
dx of AIDS
Definition
depends principally on the identification of an indicator condiction or findings in an HIV-1 seropositive patient a CD-4 cell count lower than 200.
There many be indicator conditions (AIDS-defining illness)
Term
HIV tx
Definition
HAART
Term
HSV 1 is associated with
Definition
Bell's Palsy
Term
herpetic whitlow
Definition
HSV infection of the finger caused by inoculation into open skin surface. Common in healthcare workers.
May cause fever and axillary LAD.
Treat with acyclovir. Don't mistake for paronychia. DO NOT I&D
Term
primary syphilis
secondary syphilis
tertiary syphilis
Definition
primary - hard chancre, indurated, painless ulcer with clean base.
secondary - maculopapular rash on hands and feet
tertiary - neurosyphilis
Term
dx of syphilis
Definition
primary - RPR or VDRL
confirmatory - FTA-ABS
Term
definitive diagnostic test for syphilis
Definition
dark field microscopy - visualization of spirochetes
Term
tx of syphilis
Definition
Benzathine Penacillin G
Term
causative agent of chancroid
Definition
haemophilus ducreyi - gram negative rod
Term
causative agent of syphilis
Definition
treponema pallidum
Term
buboes
Definition
unilateral tender inguinal LAD asscoaited with chancre
Term
painless ulcer at the site of ncoulation that may go unnoticed followed by tender LAD a few weeks later and constitutional sxs that develop.
Definition
lymphogranuloma venereum
Term
cause of pediculosis pubis
Definition
phthirus pubis
Term
tx of pubic lice
Definition
permethrin 1% shampoo (Elimite) - combs, clothes, and bed linens should be washed thoroughly
Term
erysipelas
Definition
celluitis usually confined to the dermis and lymphatics.
Usually caused by group A strep
Term
well demarcated, fiery red, painful lesion most commonly on the lower extremities or face. High fever and chills may be present
Definition
erysipelas
Term
common pathogens in necrotizing fasciitis
Definition
streptococus pyogenes and clostridium perfringens
Term
infection of the deep soft tissues that rapidly tracks along fascial planes - may rapidly progress to sepsis, TSS and multiorgan failure
Definition
necrotizing fasciitis
Term
inflammation of a lymph node usually caused by local skin or soft tissue bacterial infection (hemolytic strep or staph)
Definition
lymphadenitis
Term
classic and earliest symptom of tetanus
Definition
hypertonicity and contractions of the masseter muscles resulting in trismus or "lockjaw"
Term
risus sardonicus
opisthotonos
Definition
risus sardonicus - grin due to contraction of facial muscles
opisthotonos - arched back due to contraction of back muscles
Term
gonococcal arthritis
Definition
acute monoarthritis often progresses within days in a migratory or additive pattern.
MC = knees, wrists, hands, and ankles.
consider testing for HIV and syphilis
Term
erythema migrans
Definition
large, painless, well demarcated target lesion - commonly seen on the thigh, groin, or axilla
Term
borrelia burgdorferi
Definition
Lyme Disease
Term
lyme serology
Definition
IgM antibodies peak 3-6 wks after onset of sxs
IgG antibodies slowly increase and remain elevated in pts with disseminated illness.
Term
tx of lyme disease
Definition
oral doxycycline
alt = amox and cefuroxime
pregnancy = erythromycin
Term
rickettsia rickettsii
Definition
rocky mountain spotted fever
Term
rash that starts peripherally (wrists, forearms, palms, ankles, and soles) but then spreads centrally.
Definition
Rocky Mountain Spotted Fever
Term
tx of RMSF
Definition
doxycycline for 7 days
Term
dx of malaria
Definition
blood smear with Giemsa stain
Term
tx of malaria
Definition
chloroquin phosphate
if resistance is suspected - quinine sulfate and tetracycline.
Term
most serious, life threatening infection causing malaria
Definition
P. Falciparum
Term
sxs of rabies
Definition
pain at site of bite
prodromal sxs fo sore throat, fatigue, HA, N/V
encephalitis
hydrophobia
some pts may present with ascening paralysis
Term
dx of rabies
Definition
virus or viral antigen can be identified in infected tissue
four fold increase in serum antibody titers
identification of Negri bodies histologically
PCR detection of virus RNA
Term
post exposure rabies tx
Definition
clean wound thoroughly with soap
watch animal for 10 days
for known exposure - administer human rabies immunoglobulin to pts into the wound as well as the gluteal region.
active immunization - antirabies vaccine in 3 IM doses into the deltoid or thigh over a 28 day period
Term
MCC of candidiasis
Definition
candida albicans
Term
thick, white, cottage cheese like vaginal discharge
Definition
candidiasis
Term
tx of candidiasis
Definition
oral = clotrimazole or nystatin
vaginal = miconazole or clotrimazole
cutaneous = oral nystatin powder and keep skin dry
systemic candidiasis - amphotericin B or fluconazole
Term
asthma + eosinophilia
Definition
aspergillus
Term
CXR = fungus ball
Definition
aspergillus
Term
pulmonary disease associated with pigeon droppings
Definition
cryptococcosis
Term
tx of cryptococcus
Definition
amphotericin B wiht flucytosine for 2 wks followed by oral fluconazole
Term
definition of neutropenia
Definition
absolute neutrophil count < 1500
ANC < 500 = severely increased risk of infection
Term
decubitus ulcer staging
Definition
1 - skin is intact, nonblanching erythema, signs of impending ulceration may be present.
2 = partial thickness skin loss - epidermis and varying amounts of dermis
3 = full thickness skin loss - extends to subcutaneous tissue but not fascia
4 = extends into muscle, bone, joints, tendons, sinus tracts may be present
Term
wellcircumscribed raised lesion commonly confused wiht melanoma, color varies. complete excision is recommended
Definition
spitz nevi
Term
squamous cell carcinoma arising from a chronic wound (tends to be very aggressive)
Definition
Marjolin's ulcer
Term
number one cause of death due to cancer
Definition
melanoma
Term
features of melanoma
Definition
ABCDE
A = asymmetry
B = border irregularity
C = color variegation
D = diameter > 6mm
E = elevation - raised surface
Term
MC presentation of melenoma
Definition
changing mole
Term
thick silvery scaling
Definition
psoriasis
Term
removal of a scale causing pinpoint bleeding
Definition
Auspitz sign - psoriasis
Term
tx of psoriasis
Definition
corticosteroids
calcipotriene (vitamin D derivative)
Term
vitiligo
Definition
sharply demarcted areas of skin become amelanotic. MC on the face
Term
types of hypersensitivity
Definition
1 = IgE mediated (anaphylaxis, asthma)
2 = IgG (or IgM) and cytotoxic mediated
3 = antigen-antibody complexes (SLE, arthus reaction, serum sickness)
4 = T cell mediated (delayed hypersensitivity) allergic contact dermatitis, TB, transplant rejection
Term
clinical features of anaphylaxis
Definition
cutaneous - pruritis, erythema, urticaria, angioedema
respiratory - dyspnea, respiratory distress, asphyxia
CV - hypotension, shock, arrythmias
GI - abdominal pain, N/V, severe diarrhea
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