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Definition
disease that goes over population in confined area |
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Definition
disease that accumlates to pop over continent |
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Definition
drift: small changes in the virus over time. new virus strains not recognized shift: abrupt major change, 2 strains make new subtype. |
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Term
herpes zoster is a reactivaiton of _ |
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Definition
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Term
_/3 ppl will get shingles |
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Definition
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Term
more cases of herpes zoster in ages > |
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Definition
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risk factros for shingles |
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Definition
older age immunocompro local trauma of spine splenecotmy family history of shingles |
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Term
after initial infection where does herpes zoster stay dormant in? |
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Definition
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Term
reactivaiton of herpes zoster occurs when _ immunity loweers |
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Definition
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Term
what 2 peripheral sensory nerves does herpes zoster travel on |
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Definition
trigeminal thoracic ganglia |
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Term
how long can the prodrome of herpes zoster last? |
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Definition
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Term
symtpoms of herepes zoster prodrome- 6 |
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Definition
burning, los of sensation, or knife like pain headache, photophobia, fever |
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Term
with acute shingles pain occurs along? -most common sites? |
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Definition
dermatomes chest, abs, neck, eye |
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Term
in acute shingles the rash is _ |
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Definition
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Term
postherpetic nueralgia defined as |
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Definition
pain 12 days after onset of rash or after cutaneous healing |
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Term
psot herpetic neuralgia pain descr as |
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Definition
stabbing, burning, electric |
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Term
incidence and duration of post herpetic nueralgia directly related to |
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Definition
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Term
when do you treat patients for shingles? 2 |
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Definition
mod/severe pain or age >50 |
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Term
what type of med does NOT help post herpetic nueralgia |
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Definition
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Term
2 types of shingles prevention |
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Definition
variciella vaccine herpes zoster vaccine |
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Term
varicella vaccine prophylaxis: dead/ alive? attenuated/non attenuated? how mnay doses? at what times? how effective? |
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Definition
live, attenuated 2 doses- first 12-15 months, then 4-6 years 70% |
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Term
Zostovax: dead/alive; attenuated? same strain but _ x higher effectivenes? |
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Definition
live attenuatedd 14 61% reduction for effective |
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Term
do not give zostovax to? who is it reccomednded for? |
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Definition
children immune competent, age >60 |
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Term
how long does zostovax last? |
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Definition
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Term
cytomegalovirus is a _ virus |
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Definition
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Term
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Definition
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CMV lasts how long? what kind of symptoms? |
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Definition
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Term
populations at risk for CMV |
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Definition
newborns HIV- retinits stem cell/organ transplant |
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Term
congenital CMV is one of the leadings causes of _ |
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Definition
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Term
CMV in newborns can result in- 3 |
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Definition
hearing loss, vision loss, retardation |
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Term
bc fo CMV risk- _ needs to be idenitfiied of donor and receipeint of trnasplant |
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Definition
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Term
CMV can also affect _ survivial in transplant |
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Definition
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Term
immunization available for CMV prevention? |
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Definition
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Term
Meds available for CMV prevention-2 |
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Definition
valganciclovir ganciclovir |
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Term
what virus is the 7th leading cause of deaht in US? |
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Definition
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Term
flu peaks during what months? |
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Definition
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Term
what 2 classes of the flu are most common? which develops in childhood? which is more severe |
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Definition
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Term
whcih type of flu also has surface glycoproteins? what are they? |
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Definition
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Term
which glycoprotein is involved in host cell binding prior to flu virus entry |
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Definition
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Term
which glycoprotein is needed for flu virus rlease and propogation |
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Definition
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Term
flu virus is carried from _? _ tansmission can also occur |
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Definition
respiratory droplets contact |
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Term
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Definition
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Term
how long is incubation for flu virus |
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Definition
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Term
ppl at higher risk for flu complications-6 |
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Definition
< 2 yrs 65+ preggo AM. Indian BMI>40 AGE<19 w/ aspirin |
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Term
signs of the flu in 50% of patients |
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Definition
fever, sore throat, cough |
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Term
influenza can also present as _ |
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Definition
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Term
what are the complications of influenza -4 |
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Definition
exacerbation of med condtion bacteria superinfection cardiac, seizure, muscles thrombosis |
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Term
what is the Lab testing for influenza -% os sensitivity? % of specificity? |
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Definition
rapid point of service 60-80 90 |
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Term
to confirm 2009 H1N1 need what test? |
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Definition
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Term
when is rapid testins of flu not essential |
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Definition
if virus prevalent in community |
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Term
what is current recocmendation for flu vaccine? |
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Definition
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Term
flu vaccine reccomended for ages? |
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Definition
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Term
what are the 2 types of flu vaccines |
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Definition
trivalent inactivated; live attenuated |
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Term
for the TIV: how is it admin? side effect? |
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Definition
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Term
FLu Zone high dose is what type of vaccine? what age group is it for? what is a con? |
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Definition
trivalent inactivted 65+ more side effects |
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Term
brand name of the LAIV? admin? what pop is it given to? side effects? (2) |
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Definition
Flu Mist nasal spray healthy 2-49 yrs sore throat, nasal stuffiness |
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Term
what is the new reccomednation about eggs allergy and the flu |
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Definition
if had hives or rash- get TIV and monitor for 30 min |
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Term
what drug class cannot be used to PREVENT symtpoms like pain and fever flu vaccine |
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Definition
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Term
when is pharmacologic prophylaxis reccomended for influenza- 3 |
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Definition
-high risk that cant get vaccine -household w/ infected ppl -long term care facility |
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Term
when should you not get prophylaxis for influenza |
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Definition
while developing response to LAIV (2 wks after admin) |
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Term
what are the reccomended pharm prophylaxis for influenza |
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Definition
TAMIflu-oselTAMIvir relenZa-Zanamivir |
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Term
which pharm agents are not recocmended for flu prophylaxis |
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Definition
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Term
How many hours of flu symtpom onset do you want to start treatment? do you wait for lab result? |
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Definition
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Term
when may treatment be beneficial for flu even after the reccomended hrs -2 |
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Definition
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Term
what are the beenfits from treatment for flu |
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Definition
decreased duration nasal shedding of virus decrease severity |
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Term
patients who should get flu therapy? (3) |
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Definition
hospitalized severe, complicated illness the list of ppl at higher risk of complication |
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Term
almost all flu type _ is resistant to older agents ALL of type _ is resistant |
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Definition
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