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Details

Hypertension Centrally Acting Agents & others
Hypertension Centrally Acting Agents & others
18
Pharmacology
Professional
09/10/2012

Additional Pharmacology Flashcards

 


 

Cards

Term

What is clonidine commonly used for?

Definition

Resistant hypertension and in patient's who can't swallow since it comes as a patch formulation. Since the patch is changed weekly, it can help with adherence

 

Term
What formulation does clonidine come in?
Definition
Patch
Term
What side effects does clonidine have?
Definition

many side effects, including sedation, dizzziness, lethargy, dry mouth - and can aggravate depression and contribute to sexual dysfunction. If it is used first-line without a vlid reason, it may be innappropriate prescribing

 

Term
Clonidine is sometime used off-labe for what?
Definition

Opioid withdrawal to block nervousness, anxiety and to help with sleep

Term
Should clonidine be abruptly stopped?
Definition

NO! If stopped abruptly, especially at higher doses, a withdrawal syndrome with very high blood pressure, headache, anxiety, tremors, etc will result. Taper over 2-5 days

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Term
Brand name for clonidine
Definition
Catapres, Catapres TTS patch
Term
side effects of centraly-acting alpha 2 agonists
Definition
Bradycardia, dry mouth, drowsiness: start QHS
Term
should clonidine be administered in the AM or PM?
Definition
PM
Term
Should centrally - acting alpha 2 agonists be stopped abruptly?
Definition
No, doing so could cause rebound hypertension
Term
[image]
Definition
Statement. Not a question.
Term
Name the direct vasodilators
Definition

Hydralazine

Minoxidil

Term
What kind of syndrome can occur from direct vasodilators?
Definition

Lupus-like syndrome (dose and duration related)

 

Term
[image]
Definition
Statement. Not a question.
Term
Name the peripheral adrenergic antagonists
Definition

Guanethidine

Guanadrel

Term
[image]
Definition
Statement. Not a question.
Term
What are alpha blockers mostly used for?
Definition
BPH
Term
Name the Alpha Blockers
Definition

Prazosin

Terazosin

Doxazosin

Term
[image]
Definition
Statement. Not a question.
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