Shared Flashcard Set

Details

Hypersensitivity
BBD Lec 4/5 @1PM
31
Medical
Professional
04/05/2010

Additional Medical Flashcards

 


 

Cards

Term
what is hypsersensitivity?
Definition
injurious or pathologic reaction of the immune system.
Term
what is Type 1 sensitivity?
Definition
Term
what is Type 2 sensitivity?
Definition
Term
what is Type 3 sensitivity?
Definition
Term
what is Type 4 sensitivity?
Definition
Term
what receptors are in mast cells during a type 1 sensitivity?
Definition
Mast cells with Fc receptors that bind IgE
Term
what is normal IgE?
Definition
50 iu or less
Term
name of stain for white blood cells?
Definition
Wright Stain
Term
what is erythema?
Definition
dilation of blood vessels near skin surface
Term
what does mast cell release?
Definition
histamines and cytokines
Term
what are in the pre-formed granules of mast cells that are discharged?
Definition
histamines, proteases
Term
purpose of IL-4?
Definition
Term
purpose of IL-5?
Definition
Term
what do eosinophils release?
Definition
Term
what does the CD4+ Th2 cell release?
Definition
IL-4 and IL-13 to stimulate isotype switching
Term
mast cells make histamine and prostaglandin. what about basophils?
Definition
they just make histamine, no PGD2
Term
what do cysteinyl leukotrienes do?
Definition
cause edema, increased mucus secretion, smooth muscle contraction
Term
antihistamines would block which phase of the allergic reaction?
Definition
early phase
Term
a single dosage of corticosteroids would block which phase?
Definition
late phase.
Term
which phase is blocked by IgE?
Definition
both phases (early and late)
Term
allergy vaccines and interaction with Th2 cell?
Definition
Term
which phase do anti-histamines affect?
Definition
early phase only, and are not anti-inflammatory
Term
which phase do corticosteroids affect
Definition
late phase
Term
what does IL-10 do?
Definition
Term
what stimulates eosinophils?
Definition
Term
what stimulates mast cells?
Definition
Term
what stimulates IgE production?
Definition
Term
what suppresses Thelper2 reactions?
Definition
Term
how do you treat anaphylaxis?
Definition
epinephrine
Term
how to treat bronchial asthma?
Definition
albuterol (beta 2 agonist)
Term
how to treat various allergic disease?
Definition
Supporting users have an ad free experience!