Term
what is hypsersensitivity? |
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Definition
injurious or pathologic reaction of the immune system. |
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Term
what is Type 1 sensitivity? |
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Definition
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Term
what is Type 2 sensitivity? |
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Definition
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Term
what is Type 3 sensitivity? |
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Definition
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Term
what is Type 4 sensitivity? |
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Definition
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Term
what receptors are in mast cells during a type 1 sensitivity? |
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Definition
Mast cells with Fc receptors that bind IgE |
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Term
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Definition
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Term
name of stain for white blood cells? |
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Definition
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Term
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Definition
dilation of blood vessels near skin surface |
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Term
what does mast cell release? |
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Definition
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Term
what are in the pre-formed granules of mast cells that are discharged? |
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Definition
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Term
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Definition
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Term
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Definition
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Term
what do eosinophils release? |
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Definition
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Term
what does the CD4+ Th2 cell release? |
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Definition
IL-4 and IL-13 to stimulate isotype switching |
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Term
mast cells make histamine and prostaglandin. what about basophils? |
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Definition
they just make histamine, no PGD2 |
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Term
what do cysteinyl leukotrienes do? |
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Definition
cause edema, increased mucus secretion, smooth muscle contraction |
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Term
antihistamines would block which phase of the allergic reaction? |
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Definition
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Term
a single dosage of corticosteroids would block which phase? |
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Definition
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Term
which phase is blocked by IgE? |
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Definition
both phases (early and late) |
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Term
allergy vaccines and interaction with Th2 cell? |
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Definition
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Term
which phase do anti-histamines affect? |
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Definition
early phase only, and are not anti-inflammatory |
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Term
which phase do corticosteroids affect |
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Definition
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Term
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Definition
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Term
what stimulates eosinophils? |
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Definition
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Term
what stimulates mast cells? |
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Definition
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Term
what stimulates IgE production? |
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Definition
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Term
what suppresses Thelper2 reactions? |
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Definition
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Term
how do you treat anaphylaxis? |
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Definition
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Term
how to treat bronchial asthma? |
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Definition
albuterol (beta 2 agonist) |
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Term
how to treat various allergic disease? |
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Definition
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