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Hypersensitivity
ppt presentation
28
Nursing
Not Applicable
05/21/2024

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Term
Altered immune response to an antigen that results in harm
Definition
Hypersensitivity
Term
Hypersensitivity is classified by
Definition
type of immune response, immune or delayed
Term
Immiediate hypersensitivity responses
Definition
Types I, II, III
Term
antigen- lymphoctye reaction (delayed)
Definition
Type IV
Term
Systemic hypersensitivity responses type I
Definition
Type I anaphylaxis, urticaria, angioedema, rhinitis, conjunctivitis, bronchial
Term
Type II systemic hypersensitivity reacion
Definition
transfusion reaction, A B O incompatibility, autoimmune anemia, neutropenia, anti-GM disease
Immune complex-mediated reactions: vasculitis, arthritis, contact dermatitis
Term
Examples of common hypersensitivity reactions
Definition
allergic asthma, hay fever, hives
Term
Common hypersensitiviy reactions are triggered when allergen interacts with free
Definition
IgE
Term
Initial symptoms of anaphylaxis
Definition
rash/urticaria, shortness of breah/wheezing, stomach pain/nausea, facial swelling, fainting
Term
Type II cytotoxic hypersensitivity may be stimulated by
Definition
exogenous antigen ( foreign tissue cells)
Term
Results from formation of IgG or IgM antibody–antigen immune complexes in circulatory system
Definition
Type III (Immune complex-mediated) hypersensitivity
Term
Immune complexes accumulate at specific site
Definition
Type III hypersensitivity
Term
Type III hypersensitivity
Definition
Immune complex mediated hypersensitivity
Term
latex allergies are common in certain paitents
Definition
spina bifida, congenital urologic, gastrointestinal, tracheosophageal defects, multiple surgeries, diabetes requiring insulin, history of atopy
Term
latex allergy often coexists with alergy to certain foods including
Definition
kiwi, bananas, tomatoes, avocados
Term
Type I reaction manifestations
Definition
Hypertension, Wheezing, GI Or Uterine Spasm, Strider, Urticaria And Anaphylaxis
Term
Type II reaction manfistations ( tissue specific)
Definition
Bearing Manifestations, Dyspnea, Fever
Term
Type III reaction manifestations (immune mediated)
Definition
urticaria, fever, joint pain
Term
Type IV reaction manifestations
Definition
fever, erythema, itching
Term
Mild hypersensitivity responses clinical manifestations
Definition
discomfort, fatigue, lasts hours to a few days, resolve by themselves or with over the counter treatment, allergic rhinits lasting beyone a day or two may reult in localized infection
Term
clinical manifestations of moderate hypersensitivity reacions
Definition
localized pin and inflammations, difficulty breathing, loss of smell, taste, appetite, skin reactions (urticaria, atopic and contact dermatitis)
Term
Care of patient for type I reaction
Definition
maintain airway and cardiac output
Term
Care for the patient for type II reaction
Definition
manage bleeding, renal failure
Term
Care for the patient with type III reacion
Definition
remove offending antigen, interrupt inflammatory response
Term
Care for the paitent with Type IV reaction
Definition
symptom management
Term
Diagnostic tests for hypersensitivity reactions
Definition
WBCD – eosinophils often present with Type I, Radioallergosorbent test (RAST), Blood type & crossmatch, Indirect Coombs test, Direct Coombs, Immune complex assays, Complement assay
Term
Immediate treatment for anaphylaxis
Definition
epinephrine
Term
Used to treat immune-complex responses
Definition
plasmapheresis
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