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study of how the body works to maintain life |
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how physiological processes are altered in disease or injury "what when wrong?" |
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1) testable hypothesis 2) conduct and analyze experiments to test hypothesis 3) draw conclusions, do results support hypothesis 4) develop a theory |
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a general statement explaining natural phenomena that is based on proven hypothesis |
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Look at the system as a whole - disregard the elements - "can't see the forest for the trees" |
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Father of Modern Physiology - milieu interieur and milieu exterieur - preserving constant the conditions of life in the internal enviornment |
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Established HOMEOSTASIS as a unifying concept of human physiology |
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condition of uniformity which results from the adjustments of living things to changes in their enviornment |
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More definitions of Homeostasis |
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- state of equilibrium in internal - relative constance of body fluids - steady state (SYN) - resistance to change - status quo (SYN) |
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- Reference signal - Desired value - Activation threshold - Point of balance |
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* SENSOR - detects deviation from st pt * INTEGRATING CENTER - determines response * EFFECTOR - produces response |
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Regulatory Mechanisms: * Intrinsic control * Extrinsic control |
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* Intrinsic Control - built into organ being regulated * Extrinsic Control - comes from outside of organ; by nervous or endocrine systems - nervous control of body temp - can overlap |
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a condition or state in which, at any one instant, homeostatic defenses are still present but over a span of time there is a change in the regulated level |
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Rheostasis: Programmed vs Reactive |
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* Programmed - changes occur at certain phases of the life cycle; puberty, pregnancy * Reactive - changes occur in response to a stimulus that may or may not be encountered; fever, stress |
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Primary Tissues of the Body (4) |
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* Muscle * Nervous * Epithelial * Connective |
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Specialized for contraction 3 types: - skeletal: voluntary, linear - cardiac: involuntary, sorta line - smooth: involuntary, not linear |
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Consists of neurons and supporting/glial cells - neurons are specialized for conducting electrical signals |
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Nervous Tissue: - cell body - dentrites - axon - supporting/glial cells |
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*Cell body - contains nucleus, metabolic center *Dendrites - branched extensions of cell body, recieve inputs *Axon - single extensions of cedll body, conducts nerve impluses to others *Sup/Glial Cells - provide physical and functional support of neurons; 5x more abundant than neurons |
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- Lines and covers body surfaces - Consists of cells that form membranes and glands - Regularly replaced |
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Epithelial Tissue: Simple vs Stratified |
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*Simple - one cell thick, specialized for transport ~ capillaries, lung lining *Stratified - multiple layers, specialized for protection ~ skin |
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Epithelial Tissue: Squamous Columnar Cubiodal |
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Squamous - flattened Columnar - taller than wide Cubiodal - cube-shaped |
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- derived from epithelial cells - secrete onto epithelium via ducts - can be simple tubes or clusters=(acini) |
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- derived from epithelial cells - secrete hormones ~ into the blood |
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Connective Tissue Purpose? (6) |
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* Has lots of extracellular material deposited in space between its cells - Binding - Supporting - Protecting - Forming blood - Storing fats (adipose) - Filling space |
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Types of Connective Tissue: Connective Tissue Proper |
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Loose C.T. - consists of scattered fibrous proteins (colleagen) and tissue fluid `dermis of skin; blood vessels/nerves - dense fibrous c.t. is packed with fibers of collagen ~regularly arranged as in tendons or irregularly oriented as in capsules or sheaths |
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Types of Connective Tissue: Adipose |
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specialized loose connective tissue for fat synthesis, breakdown, and storage |
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Types of Connective Tissue: Cartilage |
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-specialized for support and protection -made of chondrocytes and elastic ECM -serves as precursor for bone -forms articular surfaces for joints |
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Types of Connective Tissue: Bone |
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- formed as concentric layers of calcified material - contains 3 cell types: * osteoblasts - boneforming cells * osteocytes - trapped inactive osteoblasts * osteoclasts - the bone resorbing cells |
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anatomical and functional units made of two or more primary tissues |
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groups of organs working together to maintain homeostasis |
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*intracellular - inside the cell *extracellular - outside cells -separated by cells outer membrane there is communication and movement between inter and extra |
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