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Human Anatomy and Physiology
Exam #3
58
Biology
Undergraduate 2
10/24/2012

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Term
List the steps of excitation-contraction coupling in skeletal muscle.
Definition
  1. Action potential is propagated along the sarcolemma and down the T tubules.
  2. Calcium ions are released.
  3. Calcium binds to troponin and removes the blocking action with tropomyosin.
  4. Contraction begins.
Term
List the steps of the cross bridge cycle in skeletal muscle.
Definition
  1. Cross bridge formation.
  2. The power (working) stroke.
  3. Cross bridge detachment.
  4. Cocking of myosin head.
Term
Describe the epimysium.
Definition
surrounds entire muscle
Term
Describe the endomysium.
Definition
surrounds each muscle fiber
Term
Describe the perimysium.
Definition
surrounds each muscle bundle (fascicle)
Term
Describe the deep fascia.
Definition
binds muscles into functional groups
Term
Describe sarcolemma.
Definition
plasma membrane of skeletal muscle fiber
Term
Describe sarcoplasm.
Definition
cytoplasm of a skeletal muscle fiber
Term
Describe sarcoplasmic reticulum.
Definition
series of membranous channels (modified ER) that surround each myofibril
Term
Describe myofibril.
Definition
rod-like contractile elements within a muscle fiber
Term
Describe sarcomere.
Definition
functional unit of a skeletal muscle fiber
Term
Describe A band.
Definition
area of a sarcomere with overlapping thin and thick filaments
Term
Describe I band.
Definition
area of the sarcomere containing only thin filaments
Term
Describe H band.
Definition
area in the center of the A band containing only thick filaments
Term
Which molecule creates a cross bridge?
Definition
myosin
Term
Which area contains vesicles filled with acetylcholine?
Definition
synaptic knob
Term
What is the space between the neuron and the muscle called?
Definition
synaptic cleft
Term
Which area contains receptors for acetylcholine?
Definition
motor end plate
Term
Which type of contraction is represented by a single stimulus/contraction/relaxation sequence?
Definition
twitch
Term
Which action involves a muscle producing peak tensions with visible relaxation during rapid cycles of contraction and relaxation?
Definition
incomplete tetanus
Term
Which action involves a muscle that is stimulated so frequently that the relaxation phase is completely eliminated?
Definition
complete tetanus
Term
Which action involves when a muscle is stimulated repeatedly for several seconds with a constant stimulus, the amount of tensions gradually increase to a maximum?
Definition
wave summation
Term
Endurance-type activities are best suited for what type of fiber?
Definition
slow oxidative fibers
Term
A 400M or 800M sprint is best suited for what type of fiber?
Definition
fast oxidative fibers
Term
Short-term intense movements are best suited for what type of fiber?
Definition
fast glycolytic fibers
Term
Define concentric contraction.
Definition
contraction of the muscle in which the muscle shortens and does work
Term
Define eccentric contraction.
Definition
contraction of a muscle in which the muscle contracts as it lengthens
Term
What is acetylcholine?
Definition
neurotransmitter at the neuromuscular junction
Term
What is creatine phosphate?
Definition
high-energy compound in muscle
Term
What is myoglobin?
Definition
oxygen storage molecules in muscle
Term
What is lactic acid?
Definition
a product of anaerobic glycolysis
Term
Which muscle fibers contract quickly and rely on aerobic respiration for ATP?
Definition
fast oxidative fibers
Term
Which muscle fibers are most resistant to fatigue?
Definition
slow oxidative fibers
Term
Which muscle fibers have few mitochondria?
Definition
fast glycolytic fibers
Term
What is the time between the stimulus or the electrical event and the mechanical event of contraction called?
Definition
latent period
Term
What is the time during which the muscle is shortening called?
Definition
contraction period
Term
What is the time during which the muscle is returning to its original length called?
Definition
relaxation period
Term
What is the very brief time after one stimulus during which the muscle is unresponsive to a second stimulus called?
Definition
refractory period
Term
Define action potential.
Definition
propagation of an electrical current along the sarcolemma
Term
Define resting potential.
Definition
the initial polarized state
Term
Define repolarization.
Definition
restoration of membrane potential to resting potential
Term
Define refractory period.
Definition
the time when fiber cannot be stimulated until repolarization is complete
Term
Define end plate potential.
Definition
electrical event occurring only at neuromuscular junction
Term
Define acetylcholinesterase.
Definition
enzyme released into neuromuscular junction to break down acetylcholine
Term
Define calmodulin.
Definition
cytoplasmic, calcium-binding protein
Term
What are the electrical conditions of a resting sarcolemma?
Definition
outside positive relative to the inside
Term
What happens during depolarization and generation of action potential?
Definition
production of an end plate potential at the motor end plate and consequent depolarization of adjacent areas
Term
What happens during propagation of the action potential?
Definition
increased positive charge inside sarcolemma changes the permeability of adjacent areas, opening voltage-regulated sodium ion channels
Term
What happens during repolarization?
Definition
change in sarcolemma after the wave of depolarization; sodium ion channels close and potassium ion channels open, allowing potassium ions to create a positive charge outside the membrane
Term
What are the functions of skeletal muscle?
Definition
producing movement
maintaining posture
stabilizing joints
generation of heat
Term
Which protein changes shape during the contraction cycle?
Definition
myosin
Term
Which protein slides toward the M line during contraction?
Definition
actin
Term
Which protein covers the binding site?
Definition
tropomyosin
Term
Which protein binds calcium ions and starts the contraction cycle?
Definition
troponin
Term
What is the ion released from the terminal cisternae that combines with troponin and removes the blocking action of tropomyosin, resulting in the formation of cross bridges?
Definition
calcium ions
Term
What binds calcium ions in a smooth muscle, causing contraction?
Definition
calmodulin
Term
What is the alternating contraction and relaxation of opposing layers of smooth muscle called?
Definition
peristalsis
Term
What happens during the initial stages of repolarization?
Definition
electrical conditions are restored, ions are left unbalanced
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