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What membrane of mitochondria has Porin - channel forming protein permeable to molecules up to 10,000 daltons |
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What mitochondrial membrane has Protein complexes of the electron transport chain and oxidative phosphorylation, succinate dehydrogenase, transport proteins |
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What mitochondrial compartment has : Enzymes of TCA cycle except succinate dH, enzymes of urea cycle and fatty acid oxidation, mitochondrial DNA, RNA, enzymes for transcription and protein synthesis |
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What is the cofactor for Pyruvate dehydrogenase (decarboxylation) |
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What are the two cofactors for Dihydrolipoyl transacetylase? |
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What are the two cofactors of Dihydrolipoyl dehydrogenase? |
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The five enzymes of the mitochondrial matrix are: Pyruvate dehydrogenase, dihydrolipoyl transacetylase, dihydrolipoyl dehydrogenase, ? ? ?, and ? ? ?. |
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Definition
regulatory protein kinase and regulatory protein phosphatase |
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One part of the TCA cycle is the oxidation of acetyl CoA, production of ? and reduced co-enzymes (NADH, FADH2) |
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The TCA cycle provides ? for biosynthetic pathways. |
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Another function of TCA cycle is to produce energy through oxidation of NADH, FADH2 by the ? ? ?. |
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TCA cycle is a catabolic energy producing pathway that requires |
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Tissue specificity high in ?, heart, kidney cortex, liver |
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The subcellular location of TCA cycle is mostly in the ? ? except succinate dehydrogenase which is located in the ? ? ? |
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mitochondrial matrix mitochondrial inner membrane |
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Inner mitochondrial membrane is impermeable to ?, acetyl CoA, Oxaloacetate. |
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End product of TCA cycle is ? ? |
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? allosterically inhibits isocitrateDH, KetoGluDH |
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? allosterically stimulates isocitrate dehydrogenase |
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? allosterically stimulates isocitrate dehydrogenase |
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The TCA cycle is ? by a high intramitochondrial NAD+/NADH ratio |
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NADH and FADH2 must be re-oxidized by ? ? ? in order to regenerate NAD+ and FAD so that flow through the cycle will continue. |
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The electron transport chain (etc) and cycle only function when ADP, Pi, ? are available. |
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Pyruvate dehydrogenase (PDH) is inactivated by phosphorylation of ? |
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ATP, NADH, Acetyl CoA inhibit PDH by promoting PHOSPHORYLATION of |
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Ca++ and Insulin stimulate PDH by promoting |
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Inner mitochondrial membrane is impermeable to ? |
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The end products (NADH, Acetyl CoA, ATP) of the PDH reaction promote the inactivation of PDH via a ?-? ? ? |
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Definition
non-cAMP regulatory kinase |
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Ca++ and Insulin promote activation of PDH via the ? ?;this is important in directing excess CHO towards the synthesis of ? ? ?. |
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Definition
regulatory phosphatase fat via citrate |
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