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HTH 378 Chapter 4 The Nervous System
Drugs
55
Health Care
Undergraduate 3
02/19/2013

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Term
Homeostasis
Definition
the body is in a state of maintenance
Term
Somatic does
Definition
sense and interacts with the outside world
Term
automatic does
Definition
involuntary things
Term
Sympathetic does
Definition
fight or flight
Term
Primary neurotransmitters are (4)
Definition
acetocholine, dopamine, lutemine, seratonin
Term
Five parts for homeostasis
Definition
Temperature
Acidity
Water content
Sodium content
Glucose concentrations
Term
Nerve cells are also called
Definition
neurons
Term
Neurons
Definition
Analyze and transmit information
Term
Over _____ billion neurons in system
Definition
100
Term
Four defined regions of the neuron
Definition
Cell body
Dendrites
Axon
Presynaptic terminals
Term
Stimulation of receptors by psychoactive drugs can _____ or ____ a neuron
Definition
activate, inhibit
Term
Six things that glial cells do
Definition
Provide firmness and structure to the brain
Get nutrients into the system
Eliminate waste
Form myelin
Create the blood-brain barrier
Communicate with other glia & neurons
Term
Action potential
Definition
a brief electrical signal transmitted along the axon
Term
Neurotransmitters are the “________”
Definition
messengers
Term
Resting action potential is caused by
Definition
uneven distribution of ions
Term
Action potential occurs when
Definition
sodium ions move across channels
Term
Blocking channels prevents the ____ _______ and disrupts _____ _____ _____
Definition
action potential, communication between neurons
Term
Somatic nervous system
Definition
Sensory information
Voluntary actions
Term
Automatic nervous system has what two branches
Definition
Sympathetic branch
Parasympathetic branch
Term
CNS includes
Definition
Brain
Spinal cord
Term
The somatic nervous system carries what two things and controls what one thing?
Definition
Carries sensory information into the central nervous system
Carries motor (movement) information back out to the peripheral nerves
Controls voluntary actions
Term
The neurotransmitter at neuromuscular junctions
Definition
acetylcholine
Term
Automatic nervous system monitors and controls
Definition
the body’s internal environment and involuntary functions
Term
Many psychoactive drugs affect the _____ and the ______
Definition
brain and ANS
Term
Two branches of ANS often act in ______
Definition
opposition
Term
Three functions of the CNS
Definition
Integration of information
Learning and memory
Coordination of activity
Term
Dopamine is found in the
Definition
basal ganglia and other regions
Term
What dopamine pathway is related to muscle rigidity
Definition
Nigrostriatal dopamine pathway
Term
Which dopamine pathway...
Related to psychotic behavior
Possible component of the “reward” properties of drugs
Definition
Mesolimbic dopamine pathway
Term
Acetylcholine is found in
Definition
cerebral cortex & basal ganglia
Term
Acetylcholine is involved in what three things
Definition
Alzheimer’s disease, learning, memory storage
Term
Norepinephrine regulates
Definition
level of arousal and attentiveness
Term
Norepinephrine may play a role in
Definition
initiation of food intake (appetite)
Term
Serotonin can be found in
Definition
the brain stem raphe nuclei
Term
serotonin may play a role in (5)
Definition
impulsivity, aggression, depression, control of food, and alcohol intake
Term
Hallucinogenic drugs influence _____ pathways
Definition
serotonin
Term
GABA stands for
Definition
Gamma-amino butyric acid
Term
GABA is found
Definition
in most regions of the brain
Term
Gaba is an
Definition
Inhibitory neurotransmitter
Term
Glutamate is found
Definition
most regions of the brain
Term
Glutamate is an
Definition
Excitatory neurotransmitter
Term
Endorphins
Definition
Opioid-like chemical occurring naturally in the brain
Term
Endorphins play a role in
Definition
pain relief, other functions
Term
THC like neurotransmittter
Definition
Anandamide
Term
Anandamide have some
Definition
relaxation effects
Term
What two general things do drugs do
Definition
Alter neurotransmitter availability
Interfere with reuptake
Term
Agonists
Definition
Mimic neurotransmitters
Term
Antagonist
Definition
Occupy neurotransmitter and prevent its activation
Term
chemical theories of behavior
Definition
Attempts to explain normal variations in behavior in terms of changes in brain chemistry
Term
Greek physician Hippocrates
Definition
four humors
Term
chinese philosophy
Definition
yin and yang
Term
No single biochemical theory of drug dependence has
Definition
achieved sufficient experimental support
Term
Monoamine theory of mood
Definition
mood—too little activity in monoamine systems can cause depression, too much can cause mania
Term
Ecstasy
Definition
doesn’t necessarily cause holes in the brain. However, floods brain with serotonin. When they would come down there was nothing to regulate their mood and people become suicidal.
Term
Hippocampus
Definition
rewards pathway
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