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*ACE inhibitor -mild to moderate HT -no orth static hypo -not to be used when pregers! USE ACE INHIBITOR FOR *in heart failure **in diabetics- dec development of glomerulopathies -less effective in African american |
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*ACE inhibitor *prodrug (liver metabolized) |
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*ACE inhibitor *prodrug (liver metabolized) |
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*Angiotensin Receptor Blockers (ARBs) -similar to ACE inhibitors with SE etc but no cough SE: dizziness, fetal toxicity, hyperkalemia |
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*Angiotensin Receptor Blockers (ARBs) -similar to ACE inhibitors with SE etc but no cough SE: dizziness, fetal toxicity, hyperkalemia |
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*Renin inhibitor -MOA: binds renin, inhibits the cleavage of angiotensinogen to produce AI -dec BP similar w/ARB **DONT use during preg!! |
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*Arteriolar calcium channel blocker -blocks L-type calcium channels, dec vascular resistance *often first one tried |
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*Arterial and cardiac Ca2+ channel blocker -useful against arrhythmias |
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*Arterial and cardiac Ca2+ channel blocker -useful against arrhythmias |
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*smooth muscle vasodilator -MOA: inc NO, inc K+ permeability |
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*Smooth muscle vasodilator -MOA: inc K channel opening SE: w/hirsutism |
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-used for HT crisist- moment to moment control -very toxic |
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