Term
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Definition
Amorphous (Diatomaceous earth, silica gel, silica fume) Crystalline (quartz, tridymite, cristobalite) |
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Term
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Definition
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Term
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Definition
PEL = 0.1 mg/m3 (if 100 % silica), TLV = 0.025 mg/m3 |
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Term
The Gauley Bridge disaster was an overexposure of what chemical? |
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Definition
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Term
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Definition
Progressive Massive Fibrosis in Silicosis |
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Term
Complications of silicosis |
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Definition
Emphysema, tuberculosis, cancer |
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Term
Silica is toxic to what cells? |
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Definition
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Term
A naturally occurring, silicate mineral fiber (MgSi compounds) |
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Definition
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Term
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Definition
serpertine (chrysotile) amphibole (amosite, crosidolite) |
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Term
Asbestos disease characterized by diffuse interstitial scar tissue... non-malignant. |
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Definition
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Term
3 types of cancer caused by asbestos |
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Definition
bronchogenic lung cancer pleural mesothelioma peritoneal mesothelioma |
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Term
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Definition
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Term
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Definition
National Emission standards for Hazardous Air Pollutants |
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Term
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Definition
Asbestos Hazard Emergency Response Act |
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Term
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Definition
Asbestos School Hazard and Abatement Reauthorization Act |
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Term
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Definition
Work controls - protective clothing, wet removal, etc. Respirators |
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Term
Asbestos and smoking have a ____ effect. |
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Definition
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Term
High solubility, acute lung irritants |
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Definition
SO2, HCl, NH3 Upper airway bronchoconstriction Good warning properties |
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Term
Low solubility, acute lung irritants |
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Definition
O3, NO2, phosgene Alveolar region, pulmonary edema minimal warning |
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Term
Very high reactivity, acute lung irritants |
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Definition
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Term
2 types of allergic lung disease |
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Definition
Occupational Asthma Hypersensitivity Pneumonitis |
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Term
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Definition
antigen --> b lymph --> antibodies |
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Term
____ is a clinical syndrome characterized by increased responsiveness of the tracheobronchial tree to a variety of stimuli...” |
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Definition
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Term
Asthma attacks are controlled by _____ |
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Definition
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Term
3 causes of occupational asthma |
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Definition
chemical, animal, vegetable |
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Term
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Definition
Irritant: Direct Inflammation of Mucous Membranes Allergen: Immunologic response to specific agent |
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Term
Repeated exposure to irritant = ? |
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Definition
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Term
Repeated exposure to allergens = ? |
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Definition
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Term
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Definition
Byssinosis
Caused by bacterial endotoxins |
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Term
Chronic lung disease results from ____ and ____ |
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Definition
inflammation and fibrosis |
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Term
____ is characterized by synthesis of connective tissue, space-occupying lesions, and scarring |
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Definition
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Term
____ causes increased vascular permeability, swelling, edema, and cellular changes |
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Definition
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Term
___ includes bronchitis and emphysema, and is caused by smoking, air pollution, and occupational dust. |
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Definition
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Term
3 mechanisms of airway obstruction |
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Definition
wall thickening, edema, loss of attachment sites |
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Term
Disease caused by alveolar destruction |
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Definition
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Term
____ is a marker of lung inflammation |
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Definition
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Term
lung fibrosis occurs in ___ lung disease. |
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Definition
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Term
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Definition
Coal workers Pneumoconiosis |
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Term
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Definition
progressive massive fibrosis, decreased lung function, death |
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Term
Most common way of diagnosing Pneumoconioses |
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Definition
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Term
_____ occur when coronary arteries are blocked leading to ischemia and tissue death. |
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Definition
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Term
Mechanism of PM causing heart attacks |
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Definition
Exposure --> inflammation --> Increased blood coaguability --> blood clot --> coronary blockage --> heart attack |
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Term
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Definition
Mold, animal dander, human infectious agents |
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Term
________ may be caused by tight buildings with inadequate ventilation. |
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Definition
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Term
Causes of indoor CO exposure |
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Definition
faulty heating equipment, car exhaust |
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Term
____ is the second leading cause of lung cancer in US and is a concern of indoor air pollution. |
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Definition
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Term
Itai-Itai Disease is caused by? |
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Definition
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Term
____ exposure causes siderosis, a benign pneumoconiosis |
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Definition
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Term
_____ is used in steel alloy, welding, and dry cell batteries. |
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Definition
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Term
______ is a neurotoxin that causes "wobbly-gait" disease and a form of parkinsonism. |
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Definition
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Term
_____ causes garlic breath. |
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Definition
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Term
_____ causes metal fume fever. |
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Definition
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Term
____ exposure causes Shaver's Disease, a benign pneumoconiosis, and has possible involvement with Alzheimer's. |
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Definition
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Term
_____ is used as an anticancer drug, but can also be a reproductive toxin. |
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Definition
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Term
______ exposure is what caused the "blue boys". |
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Definition
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Term
The trivalent form of _______ is most toxic, causing skin and lung cancer. It is an A_ toxin. |
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Definition
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Term
______ causes berylliosis, and lung cancer. It is an A_ toxin. |
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Definition
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Term
_____ causes corrosive holes, is an A1 toxin, causes lung cancer, and was involved in Erin Brockovich. |
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Definition
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Term
_______ is a neurotoxin that caused the Minamata contamination. |
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Definition
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Term
_____ causes a black line in the gums of those exposed, is a neurotoxin, hematopoetic toxin, nephrotoxin, and reproductive toxin. |
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Definition
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Term
Lead removal happens at blood levels greater than ___ ug/dl. |
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Definition
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Term
Material used to dissolve another material. |
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Definition
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Term
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Definition
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Term
_____ describes a liquid's tendency to evaporate. |
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Definition
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Term
Higher/Lower vapor pressure = more readily evaporates. |
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Definition
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Term
Vapor pressure increases with _____. |
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Definition
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Term
Dalton's Law of Partial Pressures |
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Definition
Total pressure is the sum of the component pressures. partial pressure = total pressure x fract. concentration where total pressure = 760mmHg |
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Term
Maximum Equilibrium concentration calculation |
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Definition
VP/760 = concentration (fractional) |
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Term
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Definition
VHR = max. equil. conc./TLV |
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Term
temperature at which the VP equals atm. press. at the surface of the liquid |
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Definition
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Term
lowest temperature at which enough vapor is given off to propagate a flame with an ignition source |
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Definition
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Term
Flash Point for flammable materials |
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Definition
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Term
Flash Point for combustible liquids |
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Definition
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Term
temperature at which there is enough vapor to support continuous combustion (for 5 seconds) |
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Definition
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Term
Fire Point is usually __ degrees F above the flash point |
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Definition
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Term
temperature at which combustion will automatically occur (self-ignition and self-sustaining) |
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Definition
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Term
lowest concentration, at or above which, in the presence of an ignition source, an explosion can occur |
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Definition
LEL, Lower Explosion Limit |
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Term
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Definition
LEL = VP at flash point/760 x 10^6 |
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Term
________ are straight chain hydrocarbons that are generally not biologically active. |
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Definition
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Term
____ is a "toxic exception" to the fact that aliphatic hydrocarbons are not biologically active. It causes: |
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Definition
n-Hexane: demyelination of axons peripheral neuropathy |
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Term
________ like alkenes and alkynes are biologically active. |
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Definition
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Term
______ have a pleasant aroma and are based off of benzenes. |
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Definition
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Term
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Definition
aplastic anemia, acute myelogenous leukemia |
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Term
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Definition
brain damage, hearing loss |
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Term
_____ hydrocarbons are synergistic effects with alcohol, cause cardiac arrhythmia with high exposure, and some are carcinogenic but most are target-organ toxic |
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Definition
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Term
________ cause methemoglobinemia |
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Definition
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Term
What is methemoglobinemia? |
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Definition
When Fe2+ oxidizes to Fe3+ |
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Term
Compounds containing amines are ____. |
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Definition
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Term
What oxygen-containing hydrocarbon is flammable? |
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Definition
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Term
________ causes blindness and can only be reversed by consuming lots of ethanol. |
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Definition
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Term
____ are aromatic hydrocarbons that are flammable, are absorbed through the skin, and are toxic to the kidney and heart. |
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Definition
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Term
____ are highly flammable hydrocarbons but are non-toxic, with the exception of ____. |
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Definition
Ketones ... methyl n-butyl ketone |
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Term
______ can be sensitizers, reactive air pollutants, or carcinogens. |
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Definition
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Term
_______ are known as cellosolves and are possible reproductive toxins. |
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Definition
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Term
Photochemical reactions plus hydrocarbons = ? |
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Definition
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Term
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Definition
Substitution, isolation, housekeeping, personal protective equipment, ventilation, training, eliminate sources of ignition |
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Term
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Definition
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Term
The ____ Act is considered the key act in OS&H because OSHA came from it. |
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Definition
Williams-Steiger Act (1970) |
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Term
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Definition
National Institute for Occupational Safety and Health |
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Term
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Definition
Occupational Safety & Health Review Commission |
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Term
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Definition
National Advisory Commission on OSH |
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Term
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Definition
National Commission on Workers’ Comp |
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Term
What organization's responsibility is in research and education? |
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Definition
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Term
____ reviews contested citations, as well as penalties and abatement periods. |
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Definition
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Term
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Definition
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Term
3 types of OSHA standards |
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Definition
Initially incorporated, permanent, emergency |
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Term
Emergency standards are effective immediately, but must be replaced by permanent standards within ____. |
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Definition
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Term
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Definition
standards which stipulate fixed requirements |
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Term
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Definition
standards that specify the end result to be reached, but not the method to get there |
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Term
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Definition
Apply to specific industries |
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Term
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Definition
Apply to industry in general |
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Term
Vinyl chloride causes ____. |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
Ethylene Oxide causes _____. |
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Definition
reproductive problems, cancer |
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Term
Methylene chloride causes ______. |
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Definition
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Term
OSHA's confined space requirements maintain that 3 positions must be held when going into a confined space... what are the conditions? |
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Definition
Attendant, Entrant, Entry Supervisor
Attendant and Entry Supervisor can be one person. |
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Term
What Supreme Court ruling requires an OSHA officer to have a warrant before searching. |
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Definition
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Term
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Definition
serious non-serious willful (“knowing” in IN)/egregious repeat failure to abate de minimus |
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Term
"Good Faith" penalty reduction |
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Definition
fixing the problem that you were cited for immediately, while the inspector is still there |
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Term
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Definition
Toxic Substances Control Act |
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Term
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Definition
PBB in cattle feed... lots of financial damages, gave OSHA authority to control new chemicals |
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Term
Three Acts as a result of TSCA |
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Definition
AHERA, Indoor Radon Abatement Act, Residential Lead-Based Paint Hazard Reduction Act |
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Term
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Definition
Resource Conservation & Recovery Act |
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Term
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Definition
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Term
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Definition
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Term
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Definition
Comprehensive Environmental Response, Compensation & Liability Act |
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Term
CERCLA created ATSDR, which stands for: |
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Definition
Agency for Toxic Substances and Disease Registry |
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Term
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Definition
Superfund Amendment & Reauthorization Act |
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Term
SARA gave the EPA additional authority in the areas of: |
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Definition
CRTK (community right to know) Underground Storage Tanks (UST) Emergency Response Indoor Air Quality hazardous waste operations and emergency response regulations for workers (HAZWOPER) |
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Term
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Definition
Nuclear Regulatory Commission |
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Term
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Definition
Energy Research and Development Agency |
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Term
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Definition
Department of Energy (originally ERDA) |
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Term
Henry’s Law is a relation that fundamentally describes |
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Definition
The amount of gas dissolved in a liquid |
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Term
Cigarette smoke interferes with which method of clearance? |
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Definition
mucociliary and phagocytosis |
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Term
Temperature inversion was a factor in which disasters? |
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Definition
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Term
Large particulates are carried out of the airstream and deposit in the lung tissues via their relatively large momentum. This process is known as? |
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Definition
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Term
Units of asbestos concentration |
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Definition
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Term
primary target organ for inorganic mercury |
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Definition
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Term
Smoking cigarettes provides significant exposure to _______. |
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Definition
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Term
The CDC's current action level for Pb is _____. |
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Definition
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Term
Metal involved in Wilson's Disease |
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Definition
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Term
Metal Fume Fever is mainly associated with ______. |
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Definition
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Term
MSDS's are required by what committee of OSHA? |
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Definition
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Term
True or False: If an OSHA inspector identifies an imminent danger during an inspection, he/she has the authority to stop the operation and order an evacuation. |
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Definition
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Term
The _______ of arterial blood is the measure of the amount of dissolved O2 in blood. |
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Definition
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Term
Which acts more quickly? Mucociliary clearance or phagocytosis? |
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Definition
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|
Term
Temperature inversions have played a critical role in air pollution disasters because? |
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Definition
They concentrate pollutants close to the ground. |
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Term
Ozone in the atmosphere primarily comes from? |
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Definition
the interaction of other pollutants with sunlight |
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Term
Factors thought to enhance the toxicity of PM2.5 are? |
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Definition
large SA, ability to penetrate the lung, chemical composition |
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Term
Why is Aerodynamic Diameter used in reference to toxic aerosols rather than normal diameter? |
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Definition
AD determines the penetration into the deepest parts of the lung |
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Term
Why is the cyclone a useful devise in air sampling? |
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Definition
It is used to obtain a sample of respirable particles. |
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Term
An approximate range for the diameter of nanoparticles is ____nm? |
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Definition
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Term
Lung condition caused by an allergic reaction in the alveolar region in the lung. |
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Definition
Hypersensitivity pneumonitis |
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Term
What disease is a major concern for PM2.5 exposure? |
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Definition
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|
Term
Over the past two years, what trend have ozone levels taken? |
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Definition
They've decreased, but are still a concern. |
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Term
Exposure to radon may cause ____. |
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Definition
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|
Term
People with obstructive lung disease usually show what in a spirometry? |
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Definition
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Term
A toxic substance found in cotton dust which may cause lung problems is _____? |
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Definition
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Term
High/Low solubility makes a substance more damaging to the alveolar region of the lung. |
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Definition
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|
Term
How do amphibole and serpentine asbestos fibers differ? |
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Definition
Amphibole are more straight |
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Term
The Gauley Bridge Disaster involved many deaths due to acute/chronic silicosis. |
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Definition
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|
Term
Muriel Rukeyser commented on the Gauley Bridge Disaster by: |
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Definition
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Term
For mixtures, the Hazard Communication Standard requires that hazard info be suppolied on the MSDS for any component greater than ___% if considered a hazardous chemical and ___% if considered a carcinogen. |
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Definition
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Term
3 characteristics of a confined space |
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Definition
Large enough for a person to enter, not intended for continuous occupancy, limited entry or exit |
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Term
If a confined space is found to contain a hazardous atmosphere, it is refereed to as a ________. |
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Definition
Permit-required confined space |
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Term
The ____ was a regulatory act initially adopted in 1977 that among other things, established the NAAQS and NESHAPS. |
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Definition
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Term
The ______ was a regulatory act adopted in 1976 that requires manufacturers to perform toxicity testing and file a PMN at least 90 days before the release of a new chemical into the market. |
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Definition
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Term
The _____ was a regulatory act initially adopted in 1976 that requires the responsibility of properly managing hazardous chemicals from "the cradle to the grave", including issues dealing with treatment, storage and disposal of chemical wastes. |
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Definition
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Term
The _____ was a regulatory act that was created a mechanism to deal with uncontrolled and abandoned hazardous waste sites, including handling emergencies. |
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Definition
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Term
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Definition
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Term
The ____ was a regulatory act that created authority for indoor air quality activities required OSHA to establish a hazardous waste operationa nd emergyresponse regulation for workers and created authority in the area of community right to know. |
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Definition
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Term
Federal agency in charge of enforcing RCRA, Superfund, SARA, etc. |
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Definition
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Term
4 Requirements that of the Hazard Communication Standard that must be provided to workers. |
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Definition
MSDS, Labeling, Training, Written Program |
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Term
What is the most toxic form of chromium? |
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Definition
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Term
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Definition
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Term
Lead biological limit for removal from work |
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Definition
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Term
Lead biological limit for return to work after being removed. |
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Definition
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Term
How long does the medical removal protection provision of the OSHA lead standard provide protection? |
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Definition
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Term
What workers' rights are protected by the medical removal protection program of the OSHA lead standard? |
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Definition
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Term
What OSHA regulated chemical (other than lead) has standards for biological monitoring and air concentrations? |
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Definition
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|
Term
What makes n-hexane and methyl n-butyl ketone toxic? |
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Definition
They are toxic metabolites. |
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Term
Result of overexposure to a toxic metabolite? |
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Definition
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|
Term
Two types of damage to nerve cells exposed to neurotoxins |
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Definition
axonal degeneration, myelin sheath degredation |
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Term
What are the three major different types of standard health effects attributed to organic solvents? |
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Definition
CNS effects, respiratory irritation, skin irritation |
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Term
What are three chemical properties that connect the liquid volume of a chemical to its equivalent vapor volume? |
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Definition
Density, MW, Molar volume |
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Term
If there is no existing OSHA standard but it can be established that a commonly recognized hazard exists, and OSHA officer can still cite an employer under the _____. |
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Definition
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Term
Flu-like symptoms caused from overexposure to metals. |
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Definition
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Term
If a worker has a wound from metal that won't seem to heal, the metal that likely caused it was _____. |
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Definition
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|
Term
Methanol can cause blindness due to what metabolite? |
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Definition
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Term
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Definition
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|
Term
Who discovered pulmonary circulation? |
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Definition
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Term
Who studied the role of O2 and CO2 in respiration? |
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Definition
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Term
Function of the respiratory system |
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Definition
Gas exchange between blood and air |
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Term
3 Functions of upper resp. tract |
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Definition
Conditions air, removes particles, speech |
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Term
Lung Structure from top to bottom |
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Definition
Trachea, Bronchi, bronchioles, terminal bronchioles, respiratory bronchioles, alveolar ducts, alveolar sacs |
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Term
2 factors affecting gas exchange in the lung periphery |
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Definition
Total Alveolar surface area and distance between the alveoli and the red blood cells. |
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|
Term
Chemical asphyxiation by CO poisoning |
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Definition
CO binds to Hb, forming carboxyhemoglobin and keeping O2 from binding to Hb |
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Term
Chemical asphyxiation by methemoglobinemia |
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Definition
Aniline + Hb --> Methemoglobinemia ... keeps hemoglobin from binding to O2 |
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|
Term
5 types of respiratory insufficiency |
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Definition
Hypoventiliation (suffocation), chemical asphyxiation, anemia, venitlatory defect, circulatory defect |
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|
Term
Obstructive/Restrictive lung disease reduces teh efficiency of airflow to the alveoli |
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Definition
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|
Term
Obstructive/Restrictive lung disease reduces lung space available for gas exchange |
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Definition
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|
Term
4 Types of lung function test |
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Definition
pO2 and pCO2, spirometry, diffusing capacity, nonuniform ventilation |
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Term
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Definition
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Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
Green: 80-100% of personal best, Yellow: 50-80% of personal best, Red: <50% of personal best |
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|
Term
____ deaths/year by indoor air pollution |
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Definition
|
|
Term
|
Definition
protect public health including sensitive groups |
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Term
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Definition
protect public welfare, such as visibility and damage to crops |
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|
Term
6 NAAQS criteria air pollutants |
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Definition
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Term
|
Definition
National Emission Standards for Hazardous Air Pollutants |
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Term
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Definition
maximum Available Control Technology |
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|
Term
Given LEL, how would you find VP at fl. pt.? |
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Definition
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|
Term
Given VP, find max equilibrium concentration. |
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Definition
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|
Term
Given TLV and max equilibrium concentration, find VHR. |
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Definition
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|
Term
|
Definition
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|
Term
Given a maximum equilibrium concentration, how do you know if a room is under flammable conditions? |
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Definition
Flammable: 6-31% ... does the max eq. conc. fall in there? |
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|
Term
Given Venous blood partial pressure and arterial blood partial pressure, how do you find the amount of O2/ml that can be delivered to a patient? |
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Definition
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|
Term
Aerodynamic diameter calculation |
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Definition
(Density)^.5(Diameter)= AD |
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|
Term
Given the concentration and Aerodynamic diameter of the particles in an aerosol, how do you find the total suspended particulate matter? |
|
Definition
Add up the concentrations |
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|
Term
Given the concentration and Aerodynamic diameter of the particles in an aerosol, find the geometric standard deviation. |
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Definition
Difference between the AD's |
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|
Term
Given the concentration and Aerodynamic diameter of the particles in an aerosol, find the geometric standard deviation. |
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Definition
Difference between the AD's |
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|
Term
In 2008, the EPA revised its ozone standard from ___ to ___. |
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Definition
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