Term
What is hormone therapy (HT) used for? |
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Definition
women who are in menopause |
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Term
When does perimenopause occur? |
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Definition
Normally between the ages of 45 and 55 |
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Term
How does hot flashes occur? |
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Definition
Decrease in estrogen causes an increase in luteinizing hormone (LH), which can result in hot flashes and night sweats
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Term
Decreased estrogen may lead to what? |
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Definition
decrease in the vaginal mucosa; vaginal dryness; burning and painful intercourse
These are vasomoter symptoms
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Term
The most effective thearpy for vasomotor symptoms is ____? |
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Definition
estrogen, which causes a decrease in LH and more stable temperature control. Estrogen improves bone density and has historically been used to prevent postmenopausal osteoporosis |
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Term
Natural products used to treat vasomotor symptoms? |
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Definition
black cohosh
red clover
evening primrose |
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Term
Should estrogen be given alone in women with a uterus? |
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Definition
NO! In women with a uterus, estrogen should not be given alone!
To do so will increase the risk of endometrial cancer |
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Term
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Definition
conjugated equine estrogens, or CEE |
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Term
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Definition
CEE plus a synthetic progesterone (medroxyprosterone acetate, or MPA) |
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Term
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Definition
A patch.
It is a combo of estradiol and MPA (which is used in women with uterus) |
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Term
Some prescribers believe estradiol is safer, why? |
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Definition
it is produced naturally in (pre-menopausal) women and it was the hormoe from pregnant mares urine that was used in the WH trials |
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Term
Estrogens increase the risk of? |
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Definition
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Term
Estrogen in any form has what contraindications? |
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Definition
Undiagnosed abnormal genital bleeding
Active or past breast cancer
Known or suspected estrogen-dependednt cancer
Active or past deep vein thrombosis or pulmonary embolism
Active or recent arterial thromboembolic disease (e.g. stroke, myocardial infarction)
Liver dysfunction or disease
Known or suspected pregnancy
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Term
Benefits of topical formulations, given as a patch, gel or emulsion? |
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Definition
bypass first dose metabolism, and lower doses can be used. Topical formulatioins usually causes less nausea and may expose the woman to lower systemic estrogen.
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Term
Benefits of Vaginal products? |
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Definition
most usefull for patients who have vaginal symptoms (dryness, painful intercourse) only, since these do not expose the woman to risks from systemic estrogen.
These include estrogen vaginal cream or the vaginal ring (Femring)
Due to bypassing the liver, topical formulations do not affect cholesterol levels. Estrogen typically increase TG and increase HDL. |
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Term
Brand name for estradiol transdermal system |
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Definition
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Term
Brand name for conjugated estrogens tablet |
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Definition
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Term
Brand name for conjugated estrogens cream |
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Definition
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Term
Brand name for conjugated estrogens/medroxyprogesterone acetate tablet |
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Definition
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Term
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Definition
Statement. Not a question. |
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Term
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Definition
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Term
How often should Vivelle-Dot patch be applied? |
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Definition
twice - a - week application |
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Term
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Definition
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Term
Increasingly, older males are requesting testosterone therapy for puported health claims, including increased muscle mass and bone density, improved sexual interest (increased libido), sharpened memory and concentration, and increased energy. The use of testosterone replacement is controversial in what whay?
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Definition
primay risk is whether the use of testosterone increases prostat cancer risk. Testosterone can also increase cholesterol levels and cause liver damage
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Term
Appropriate indications for testosterone use? |
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Definition
men with low prostate cancer risk who have a low testosterone level and a related condition, such as low muscle mass. It should not be used routinely for normal aging until the health risk are better quantified.
Another reason for the increase in testosterone prescriptions has been due to the restriction on PDE5 I in the medicare formulary - which led men and their physicians to consider other options
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Term
Should men at high risk for prostate cancer use testosterone products? |
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Definition
NO!
So, I assume this includes black men. Also, if one is on a 5-α-reducatase inhibitor for BPH that blocks the conversion of testosterone to its active form it would not make much sense to give another drug that provides testosterone directly |
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Term
Name some testosterone products |
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Definition
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Term
Does the androgel pump need priming? |
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Definition
Yes. To prime AndroGel, fully push down ont he pump 3 times.
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Term
Androgel Patient Counseling |
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Definition
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