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HomeWork Vocab
Vocab from first problems for HW 13 and 14
31
Biology
Undergraduate 4
12/14/2013

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Term
Sequence tagged sites (STSs)
Definition
unique DNA sequences that serve as molecular markers
Term
whole-genome shotgun sequencing
Definition
a genome sequencing strategy that voids physical mapping
Term
DNA array
Definition
fragments of DNA on a chip
Term
Alternative RNA splicing
Definition
the joining together of the exons of a gene in different combinations.
Term
Physical map
Definition
a map showing the order of cloned inserts of DNA
Term
SNP
Definition
a polymorphic single-base site.
Term
Induction
Definition
stimulation of protein synthesis by a specific molecule.
Term
Repressor
Definition
negative regulator.
Term
Operator
Definition
site to which repressor binds.
Term
Catabolite repression
Definition
glucose prevents expression of catabolic operons.
Term
Reporter gene
Definition
often fused to regulatory regions of genes whose expression is being monitored.
Term
attenuation
Definition
gene regulation involving premature termination of transcription.
Term
basal factors
Definition
bind to promoters
Term
transcriptional silencing
Definition
heterochromatin
Term
activators
Definition
bind to enhancers
Term
Imprinting
Definition
pattern of expression is dependent on which parent transmitted the allele
Term
RNAi
Definition
prevents or reduces gene expression post transcriptionally.
Term
coactivators
Definition
bind to activators
Term
homomers
Definition
multimers of identical subunits
Term
heteromers
Definition
multimers of nonidentical subunits
Term
ubiquitination
Definition
marks a protein for deradation
Term
Oligonucleotide
Definition
a short DNA fragment that can be synthesized by a machine.
Term
Vector
Definition
a DNA molecule used for transporting replicating, and purifying a DNA fragment
Term
Sticky ends
Definition
short single stranded sequences found at the ends of many restriction fragments.
Term
Recombinant DNA
Definition
contains genetic material from two different organisms.
Term
Reverse translation
Definition
computational method for determining the possible sequence of base pairs associated with a particular region of a polypeptide.
Term
Genomic library
Definition
a collection of the DNA fragments of a given species, inserted into a vector.
Term
Genomic equivalent
Definition
the number of DNA fragments that are sufficient in aggregate length to contain the entire genome of a specified organism.
Term
cDNA
Definition
DNA copied from RNA by reverse transcriptase.
Term
PCR
Definition
efficient and rapid technique for amplifiying the number of copies of a DNA fragment.
Term
hybridization
Definition
stable binding of single-stranded DNA molecules to each other.
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