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HIV Pharmacotherapy
Pharm 2 Exam 1
26
Health Care
Graduate
02/04/2009

Additional Health Care Flashcards

 


 

Cards

Term

NRTI's

Definition

Abcavir

Didanosine

Lamivudine

Stavudine

Zidovudine

Term
NNRTI's
Definition

Nevirapine

Delavirdine

Efavirenz

Term
Abacavir AE
Definition

Hypersensitivity

fever, rash, myalgia, arthralgia

GI

Term
Abacavir contraindications
Definition

prior sensitivity

MI risk!!

Term
Didanosine AE
Definition

Pancreatitis

Diarrhea

Peripheral Neuropathy

Term
Didanosine contraindications/drug interactions
Definition

MI risk

 

Tenovir, antifungals, fluroquinolones

Term
Lamivudine AE
Definition

Lactic Acidosis

 

*****BEST TOLERATED*****

Term
Best Tolerated NRTI
Definition
Lamivudine
Term
Stavudine AE
Definition

Pancreatitis

Peripheral neuropathy

neuromuscular weakness

Term
Dosing for Stavudine is based on
Definition
wt.
Term

Best CNS penetrator of NRTI's

Definition

Zidovudine

Term
Zidovudine AE
Definition

bone marrow suppression

GI

Term

Potentially fatal AE's of NRTI's

Definition

lactic acidosis

hepatomegaly w/ steatosis

Term
what increases fatal AE's of NRTI's
Definition
combo tx w/ didanosine
Term
Nevirapine AE
Definition

Rash-SJS

 

Hepatotoxic

Term
Contraindications Nevirapine
Definition

women CD4 > 250

Men > 400

Term

Drug interactions Nevirapine

Definition

Midazolam

Rifampin

Triazolam

Rifabutin

OTC's

Protease inhibitors

Term
Only NNRTI's as 1st line tx
Definition
Efavirenz
Term
Efavirenz AE
Definition

nightmares

CNS

insomnia

hepatotoxic

Term
Efavirenz Contraindications
Definition
 NO PREGO
Term

Efavirenz Drug interactions

Definition

P 3A4 inducer

self, BDPZ

Term

What tests should be ran when on Zidovudine?

Definition
CBC before and q 4 wks
Term
what reduces metabolism of didanosine?
Definition
food, acidity
Term
AE of Emtricitabine
Definition

HA GI Rash

Hyperpigmentation of palms and soles!!!!

Term
Tenofovir AE
Definition
GI and not with some other NRTI's
Term
Efavirenz works against what type of HIV
Definition
HIV-1
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