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-1600s -First to really start observing microbes under the microscope -claim to fame: first to use the term "cell" |
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-1600s -made better microscopes and lenses that could see smaller things -claim to fame: first to observe bacteria |
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-1800s -developed a lot of tools |
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-1800s -swan neck flask experiment -claim to fame: proved spontaneous generation does not really occur -was the forefront for developing vaccines for anthrax and rabies |
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-1800s -developed a set of rules that defines how a particular organism causes a particular disease -claim to fame: Koch's postulates |
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-1950s -demonstrated that DNA is outside of the nucleus in eukaryotes -this lead to the theory of endosymbiosis |
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chloroplasts derive from a cyanobacteria that is taken up through the cell, which ultimately lead to a similar discovery for mitochondria |
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1. the microorganism or other pathogen must be present in all cases of the disease 2. the pathogen can be isolated from the diseased host and grown in pure culture 3. the pathogen from the pure culture must cause the disease when inoculated into a healthy, susceptible laboratory animal 4. the pathogen must be reisolated from the new host and shown to be the same as the originally inoculated pathogen |
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-1970s-1980s -worked with molecular taxonomy -claim to fame: developed a 3 kingdom tree of life |
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-the concept that all infectious and contagious diseases are caused by living microorganisms -lead to the study of bacteriology -Pasteur, Koch, Listeur |
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-1800s -claim to fame: pioneer to antiseptic surgery |
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